Reactome Pathway Database

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MAP kinase activation Show undefined attributes

compartment

created [InstanceEdit:10201029] Weiser, Joel, 2025年08月27日

dbId 10306424

displayName MAP kinase activation

eventOf

[Pathway:R-CFA-448424] Interleukin-17 signaling - Canis familiaris
[Pathway:R-CFA-168164] Toll Like Receptor 3 (TLR3) Cascade - Canis familiaris
[Pathway:R-CFA-975138] TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation - Canis familiaris
[Pathway:R-CFA-166058] MyD88:MAL(TIRAP) cascade initiated on plasma membrane - Canis familiaris

evidenceType [EvidenceType:9965817] inferred by electronic annotation

goBiologicalProcess [GO_BiologicalProcess:172358] stress-activated MAPK cascade

hasDiagram true

hasEHLD false

hasEvent

inferredFrom

[Pathway:R-HSA-450294] MAP kinase activation - Homo sapiens

isInDisease false

isInferred true

maxDepth 5

name

MAP kinase activation

releaseDate 2025年09月18日

schemaClass Pathway

species

[Species:49646] Canis familiaris

stId R-CFA-450294

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

(inferredTo)

[Pathway:R-HSA-450294] MAP kinase activation

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