Reactome Pathway Database

Schema > Reaction > Entries

Integrin alpha IIb beta3 T779 phosphorylation blocks SHC binding Show undefined attributes

catalystActivity

[CatalystActivity:10231818] protein serine/threonine kinase activity of AKT1/PDK1 [plasma membrane]

category transition

compartment

[Compartment:876] plasma membrane

created [InstanceEdit:10201029] Weiser, Joel, 2025年08月27日

dbId 10231820

displayName Integrin alpha IIb beta3 T779 phosphorylation blocks SHC binding

eventOf

[Pathway:R-CFA-354192] Integrin signaling - Canis familiaris

evidenceType [EvidenceType:9965817] inferred by electronic annotation

followingEvent

[Reaction:R-CFA-432096] Activated integrin alphaIIb beta3 binds SHC1 - Canis familiaris

inferredFrom

[Reaction:R-HSA-432110] Integrin alpha IIb beta3 T779 phosphorylation blocks SHC binding - Homo sapiens

input

[Complex:R-CFA-114514] Integrin alphaIIb:beta3 [plasma membrane]

isInDisease false

isInferred true

maxDepth 1

name

Integrin alpha IIb beta3 T779 phosphorylation blocks SHC binding

output

[Complex:R-CFA-432105] Integrin alpha IIb p(T779)-beta 3 [plasma membrane]

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:49646] Canis familiaris

stId R-CFA-432110

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-CFA-354192] Integrin signaling

(precedingEvent)

[Reaction:R-CFA-432096] Activated integrin alphaIIb beta3 binds SHC1

(inferredTo)

[Reaction:R-HSA-432110] Integrin alpha IIb beta3 T779 phosphorylation blocks SHC binding

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