Reactome Pathway Database

Schema > Reaction > Entries

Activated integrin alphaIIb beta3 binds SHC1 Show undefined attributes

category binding

compartment

created [InstanceEdit:10201029] Weiser, Joel, 2025年08月27日

dbId 10231812

displayName Activated integrin alphaIIb beta3 binds SHC1

eventOf

[Pathway:R-CFA-354192] Integrin signaling - Canis familiaris

evidenceType [EvidenceType:9965817] inferred by electronic annotation

followingEvent

[BlackBoxEvent:R-CFA-443905] SHC1 bound to integrin alphaIIb beta3 is phosphorylated somehow - Canis familiaris

inferredFrom

[Reaction:R-HSA-432096] Activated integrin alphaIIb beta3 binds SHC1 - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

Activated integrin alphaIIb beta3 binds SHC1

output

[Complex:R-CFA-432098] Integrin alphaIIb beta 3:p(Y530)-SRC:CSK:Talin:RIAM complex:SHC [plasma membrane]

precedingEvent

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:49646] Canis familiaris

stId R-CFA-432096

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-CFA-354192] Integrin signaling

(precedingEvent)

[BlackBoxEvent:R-CFA-443905] SHC1 bound to integrin alphaIIb beta3 is phosphorylated somehow

(inferredTo)

[Reaction:R-HSA-432096] Activated integrin alphaIIb beta3 binds SHC1

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