Reactome Pathway Database

Schema > Reaction > Entries

G6PC hydrolyzes G6P to Glc and Pi (liver) Show undefined attributes

catalystActivity

[CatalystActivity:10312437] glucose-6-phosphatase activity of G6PC [endoplasmic reticulum membrane]

category transition

compartment

created [InstanceEdit:10309703] Weiser, Joel, 2025年08月27日

dbId 10312439

displayName G6PC hydrolyzes G6P to Glc and Pi (liver)

eventOf

[Pathway:R-BTA-70263] Gluconeogenesis - Bos taurus

evidenceType [EvidenceType:9965817] inferred by electronic annotation

inferredFrom

[Reaction:R-HSA-71825] G6PC hydrolyzes G6P to Glc and Pi (liver) - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

G6PC hydrolyzes G6P to Glc and Pi (liver)
alpha-D-Glucose 6-phosphate + H2O => alpha-D-Glucose + Orthophosphate (G6PC - liver)

output

precedingEvent

[Reaction:R-BTA-198513] SLC7A4 exchanges G6P for Pi across the ER membrane - Bos taurus

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:48898] Bos taurus

stId R-BTA-71825

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-BTA-70263] Gluconeogenesis

(inferredTo)

[Reaction:R-HSA-71825] G6PC hydrolyzes G6P to Glc and Pi (liver)

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