Reactome Pathway Database

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Activation of Matrix Metalloproteinases Show undefined attributes

created [InstanceEdit:10309703] Weiser, Joel, 2025年08月27日

dbId 10422785

displayName Activation of Matrix Metalloproteinases

eventOf

[Pathway:R-BTA-1474228] Degradation of the extracellular matrix - Bos taurus

evidenceType [EvidenceType:9965817] inferred by electronic annotation

goBiologicalProcess [GO_BiologicalProcess:261789] extracellular matrix disassembly

hasDiagram true

hasEHLD false

hasEvent

inferredFrom

[Pathway:R-HSA-1592389] Activation of Matrix Metalloproteinases - Homo sapiens

isInDisease false

isInferred true

maxDepth 2

name

Activation of Matrix Metalloproteinases

releaseDate 2025年09月18日

schemaClass Pathway

species

[Species:48898] Bos taurus

stId R-BTA-1592389

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-BTA-1474228] Degradation of the extracellular matrix

(hasEncapsulatedEvent)

[Pathway:R-BTA-5625886] Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3

(inferredTo)

[Pathway:R-HSA-1592389] Activation of Matrix Metalloproteinases

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