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gain_of_function of p-6Y-ERBB2 TMD/JMD mutants (RAS):EGF:p-6Y-EGFR [plasma membrane] Show undefined attributes

created [InstanceEdit:9665919] Orlic-Milacic, Marija, 2019年11月01日

dbId 9665918

diseaseEntity [Complex:R-HSA-9665917] p-6Y-ERBB2 TMD/JMD mutants (RAS):EGF:p-6Y-EGFR [plasma membrane]

displayName gain_of_function of p-6Y-ERBB2 TMD/JMD mutants (RAS):EGF:p-6Y-EGFR [plasma membrane]

functionalStatus

[FunctionalStatus:2362351] gain_of_function via non_conservative_missense_variant

normalEntity [CandidateSet:R-HSA-1963587] Phosphorylated ERBB2:EGFR heterodimers [plasma membrane]

schemaClass EntityFunctionalStatus

Referrals

(entityFunctionalStatus)

[Reaction:R-HSA-9665698] Phosphorylated heterodimers of ERBB2 TMD/JMD mutants and EGFR bind GRB2:SOS1

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