Reactome Pathway Database

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gain_of_function of p21 RAS:GTP:moderate kinase activity BRAF mutants [plasma membrane] Show undefined attributes

created [InstanceEdit:8936672] Rothfels, Karen, 2016年08月22日

dbId 8936673

diseaseEntity [Complex:R-HSA-8936669] p21 RAS:GTP:moderate kinase activity BRAF mutants [plasma membrane]

displayName gain_of_function of p21 RAS:GTP:moderate kinase activity BRAF mutants [plasma membrane]

functionalStatus

[FunctionalStatus:2362351] gain_of_function via non_conservative_missense_variant

modified [InstanceEdit:9631717] Wu, G, 2018年12月12日

normalEntity [Complex:R-HSA-5672729] p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane]

schemaClass EntityFunctionalStatus

Referrals

(entityFunctionalStatus)

[Reaction:R-HSA-8936676] Moderate kinase activity BRAF mutants:RAS:GTP homo/heterodimerize

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