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Second pathway for completion of human DNA base excision-repair: reconstitution with purified proteins and requirement for DNase IV (FEN1). Show undefined attributes

author

[Person:113907] Klungland, A
[Person:111150] Lindahl, T

dbId 111248

displayName Second pathway for completion of human DNA base excision-repair: reconstitution with purified proteins and requirement for DNase IV (FEN1).

journal EMBO J

modified [InstanceEdit:1458674] D'Eustachio, P, 2011年07月22日

pages 3341-8

pubMedIdentifier 9214649

schemaClass LiteratureReference

title Second pathway for completion of human DNA base excision-repair: reconstitution with purified proteins and requirement for DNase IV (FEN1).

url http://www.ncbi.nlm.nih.gov/pubmed/9214649

volume 16

year 1997

Referrals

(literatureReference)

[Pathway:R-HSA-73933] Resolution of Abasic Sites (AP sites)
[Summation:111246] While the single nucleotide replacement pathway appears to f...
[Pathway:R-HSA-110373] Resolution of AP sites via the multiple-nucleotide patch replacement pathway
[Pathway:R-HSA-5651801] PCNA-Dependent Long Patch Base Excision Repair
[Reaction:R-HSA-5651809] LIG1, APEX1 and PCNA:POLD,POLE:RPA:RFC dissociate from repaired DNA
[Reaction:R-HSA-5651805] LIG1 bound to APEX1 and PCNA ligates SSB
[Reaction:R-HSA-110363] FEN1 bound to PCNA and APEX1 cleaves flap ssDNA
[Reaction:R-HSA-110368] POLD,POLE-mediated DNA strand displacement synthesis
[Reaction:R-HSA-110364] PCNA:POLD,POLE:RPA:RFC and FEN1 bind APEX1
[Pathway:R-HSA-110362] POLB-Dependent Long Patch Base Excision Repair
[Reaction:R-HSA-5651782] FEN1 bound to POLB cleaves displaced DNA strand (flap)
[Reaction:R-HSA-5649883] POLB-mediated DNA strand displacement synthesis
[Reaction:R-HSA-5649854] Recruitment of POLB to oxidatively damaged AP site
[BlackBoxEvent:R-HSA-5649856] Oxidative damage to the AP site
[Reaction:R-HSA-5687664] FEN1 cleaves displaced ssDNA flaps during MMEJ

(author)

[Person:111150] Lindahl, T
[Person:113907] Klungland, A

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