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Table of Contents

April 2024

More than 700,000 people are currently displaced in Cabo Delgado province due to organised armed group attacks. This displacement severely affected the access of internally displaced person to essential healthcare exacerbating the vulnerability to infectious diseases. Badia-Rius et al, 2024.

Image Credit: MUNTI TEC / The MENTOR Initiative

Viewpoints

Research Articles

Biased virus transmission following sequential coinfection of Aedes aegypti with dengue and Zika viruses

Jiameng Peng, Meichun Zhang, Gang Wang, Dongjing Zhang, Xiaoying Zheng, Yongjun Li

PLOS Neglected Tropical Diseases: published April 1, 2024 | https://doi.org/10.1371/journal.pntd.0012053

Venom diversity in Naja mossambica: Insights from proteomic and immunochemical analyses reveal intraspecific differences

Konrad K. Hus, Justyna Buczkowicz, Monika Pietrowska, Vladimír Petrilla, Monika Petrillová, Jaroslav Legáth, Thea Litschka-Koen, Aleksandra Bocian

PLOS Neglected Tropical Diseases: published April 1, 2024 | https://doi.org/10.1371/journal.pntd.0012057

Impact of Strongyloides stercoralis infection on complement activation in Type 2 diabetes mellitus: Insights from a clinical and anthelmintic intervention study

Anuradha Rajamanickam, Bindu Dasan, Saravanan Munisankar, Sujatha Nott, Pradeep A. Menon, Fayaz Ahamed Shaik, Ponnuraja Chinnaiyan, Thomas B. Nutman, Subash Babu

PLOS Neglected Tropical Diseases: published April 2, 2024 | https://doi.org/10.1371/journal.pntd.0012048

Domestic dogs in indigenous Amazonian communities: Key players in Leptospira cycling and transmission?

Diego A. Guzmán, Eduardo Diaz, Carolina Sáenz, Hernán Álvarez, Rubén Cueva, Galo Zapata-Ríos, Belén Prado-Vivar, Mercy Falconí, Talima Pearson, Veronica Barragan

PLOS Neglected Tropical Diseases: published April 3, 2024 | https://doi.org/10.1371/journal.pntd.0011671

Comparative proteomic analysis of the hemolymph and salivary glands of Rhodnius prolixus and R. colombiensis reveals candidates associated with differential lytic activity against Trypanosoma cruzi Dm28c and T. cruzi Y

Hamilton J. Barbosa, Yazmin Suárez Quevedo, Arlid Meneses Torres, Gustavo A. Gaitán Veloza, Julio C. Carranza Martínez, Daniel A. Urrea-Montes, Carlos Robello-Porto, Gustavo A. Vallejo

PLOS Neglected Tropical Diseases: published April 3, 2024 | https://doi.org/10.1371/journal.pntd.0011452

Amoxicillin/clavulanate in combination with rifampicin/clarithromycin is bactericidal against Mycobacterium ulcerans

Emma Sáez-López, Ana C. Millán-Placer, Ainhoa Lucía, Santiago Ramón-García

PLOS Neglected Tropical Diseases: published April 4, 2024 | https://doi.org/10.1371/journal.pntd.0011867

Snakebite envenoming: A systematic review and meta-analysis of global morbidity and mortality

Afsana Afroz, Bodrun Naher Siddiquea, Hasina Akhter Chowdhury, Timothy NW Jackson, Andrew D. Watt

PLOS Neglected Tropical Diseases: published April 4, 2024 | https://doi.org/10.1371/journal.pntd.0012080

Programmatic considerations and evidence gaps for chikungunya vaccine introduction in countries at risk of chikungunya outbreaks: Stakeholder analysis

Megan Auzenbergs, Clara Maure, Hyolim Kang, Andrew Clark, Oliver Brady, Sushant Sahastrabuddhe, Kaja Abbas

PLOS Neglected Tropical Diseases: published April 4, 2024 | https://doi.org/10.1371/journal.pntd.0012075

Citizens can help to map putative transmission sites for snail-borne diseases

Julius Tumusiime, Noelia Valderrama Bhraunxs, Grace Kagoro-Rugunda, Daisy Namirembe, Christian Albrecht, Ronald Twongyirwe, Casim Umba Tolo, Liesbet Jacobs, Tine Huyse

PLOS Neglected Tropical Diseases: published April 4, 2024 | https://doi.org/10.1371/journal.pntd.0012062

Serological diagnosis of soil-transmitted helminth (Ascaris, Trichuris and hookworm) infections: A scoping review

Sara Roose, Fiona Vande Velde, Johnny Vlaminck, Peter Geldhof, Bruno Levecke

PLOS Neglected Tropical Diseases: published April 4, 2024 | https://doi.org/10.1371/journal.pntd.0012049

Transcriptional signatures in human macrophage-like cells infected by Leishmania infantum, Leishmania major and Leishmania tropica

Aurora Diotallevi, Federica Bruno, Germano Castelli, Giuseppe Persico, Gloria Buffi, Marcello Ceccarelli, Daniela Ligi, Ferdinando Mannello, Fabrizio Vitale, Mauro Magnani, Luca Galluzzi

PLOS Neglected Tropical Diseases: published April 5, 2024 | https://doi.org/10.1371/journal.pntd.0012085

Protoplast-mediated transformation of Madurella mycetomatis using hygromycin resistance as a selection marker

Saskia du Pré, Mickey Konings, Dorenda J. A. Schoorl, Ahmed H. Fahal, Mark Arentshorst, Arthur F. J. Ram, Wendy W. J. van de Sande

PLOS Neglected Tropical Diseases: published April 5, 2024 | https://doi.org/10.1371/journal.pntd.0012092

Severe leptospirosis in tropical and non-tropical areas: A comparison of two french, multicentre, retrospective cohorts

Jérôme Allyn, Arnaud-Félix Miailhe, Benjamin Delmas, Lucas Marti, Nicolas Allou, Julien Jabot, Jean Reignier

PLOS Neglected Tropical Diseases: published April 10, 2024 | https://doi.org/10.1371/journal.pntd.0012084

Diagnostic accuracy of DPP Fever Panel II Asia tests for tropical fever diagnosis

Sandhya Dhawan, Sabine Dittrich, Sonia Arafah, Stefano Ongarello, Aurelian Mace, Siribun Panapruksachat, Latsaniphone Boutthasavong, Aphaphone Adsamouth, Soulignasak Thongpaseuth, Viengmon Davong, Manivanh Vongsouvath, Elizabeth A. Ashley, Matthew T. Robinson, Stuart D. Blacksell

PLOS Neglected Tropical Diseases: published April 10, 2024 | https://doi.org/10.1371/journal.pntd.0012077

Assessing and managing the risk of Aedes mosquito introductions via the global maritime trade network

Janna R. Willoughby, Benjamin A. McKenzie, Jordan Ahn, Todd D. Steury, Christopher A. Lepzcyk, Sarah Zohdy

PLOS Neglected Tropical Diseases: published April 10, 2024 | https://doi.org/10.1371/journal.pntd.0012110

Comparison of two approaches to measuring clean faces as part of the facial cleanliness component of the SAFE trachoma elimination strategy

Sheila K. West, Beatriz Munoz, Harran Mkocha, Matthew C. Lynch, Catherine Gracewello, Mabula Kasubi, Meraf A. Wolle

PLOS Neglected Tropical Diseases: published April 10, 2024 | https://doi.org/10.1371/journal.pntd.0012090

Diagnosis of soil-transmitted helminth infections with digital mobile microscopy and artificial intelligence in a resource-limited setting

Johan Lundin, Antti Suutala, Oscar Holmström, Samuel Henriksson, Severi Valkamo, Harrison Kaingu, Felix Kinyua, Martin Muinde, Mikael Lundin, Vinod Diwan, Andreas Mårtensson, Nina Linder

PLOS Neglected Tropical Diseases: published April 11, 2024 | https://doi.org/10.1371/journal.pntd.0012041

Helminth exposure and immune response to the two-dose heterologous Ad26.ZEBOV, MVA-BN-Filo Ebola vaccine regimen

Houreratou Barry, Edouard Lhomme, Mathieu Surénaud, Moumini Nouctara, Cynthia Robinson, Viki Bockstal, Innocent Valea, Serge Somda, Halidou Tinto, Nicolas Meda, Brian Greenwood, Rodolphe Thiébaut, Christine Lacabaratz

PLOS Neglected Tropical Diseases: published April 11, 2024 | https://doi.org/10.1371/journal.pntd.0011500

Endemic status of urogenital schistosomiasis and the efficacy of a single-dose praziquantel treatment in unmapped rural farming communities in Oyo East Local Government Area, Oyo State, Nigeria

Alexander B. Odaibo, Adenike K. Komolafe, Taiwo O. Olajumoke, Kanyinsola D. Diyan, Damilare A. Aluko, Oluwatunmininu A. Alagbe, Oluwafemi A. Ajagbe, David B. Olarinloye

PLOS Neglected Tropical Diseases: published April 15, 2024 | https://doi.org/10.1371/journal.pntd.0012101

Ginkgo biloba attenuated detrimental inflammatory and oxidative events due to Trypanosoma brucei rhodesiense in mice treated with melarsoprol

Janet Khatenje Wendo, James Mucunu Mbaria, James Nyabuga Nyariki, Alfred Orina Isaac

PLOS Neglected Tropical Diseases: published April 15, 2024 | https://doi.org/10.1371/journal.pntd.0012103

Extant interspecific hybridization among trematodes within the Schistosoma haematobium species complex in Nigeria

Oluwaremilekun G. Ajakaye, Elisha E. Enabulele, Joshua B. Balogun, Oyetunde T. Oyeyemi, Michael E. Grigg

PLOS Neglected Tropical Diseases: published April 15, 2024 | https://doi.org/10.1371/journal.pntd.0011472

The elimination of human African trypanosomiasis: Monitoring progress towards the 2021–2030 WHO road map targets

Jose R. Franco, Gerardo Priotto, Massimo Paone, Giuliano Cecchi, Agustin Kadima Ebeja, Pere P. Simarro, Dieudonne Sankara, Samia B. A. Metwally, Daniel Dagne Argaw

PLOS Neglected Tropical Diseases: published April 16, 2024 | https://doi.org/10.1371/journal.pntd.0012111

Machine learning for predicting Chagas disease infection in rural areas of Brazil

Fabio De Rose Ghilardi, Gabriel Silva, Thallyta Maria Vieira, Ariela Mota, Ana Luiza Bierrenbach, Renata Fiuza Damasceno, Lea Campos de Oliveira, Alexandre Dias Porto Chiavegatto Filho, Ester Sabino

PLOS Neglected Tropical Diseases: published April 16, 2024 | https://doi.org/10.1371/journal.pntd.0012026

Post-kala-azar dermal leishmaniasis (PKDL) drug efficacy study landscape: A systematic scoping review of clinical trials and observational studies to assess the feasibility of establishing an individual participant-level data (IPD) platform

Sauman Singh-Phulgenda, Rishikesh Kumar, Prabin Dahal, Abdalla Munir, Sumayyah Rashan, Rutuja Chhajed, Caitlin Naylor, Brittany J. Maguire, Niyamat Ali Siddiqui, Eli Harriss, Manju Rahi, Fabiana Alves, Shyam Sundar, Kasia Stepniewska, Ahmed Musa, Philippe J. Guerin, Krishna Pandey

PLOS Neglected Tropical Diseases: published April 16, 2024 | https://doi.org/10.1371/journal.pntd.0011635

Local amphotericin B therapy for Cutaneous Leishmaniasis: A systematic review

Líndicy Leidicy Alves, Mariana Lourenço Freire, Isadora Lana Troian, Eliane de Morais-Teixeira, Gláucia Cota

PLOS Neglected Tropical Diseases: published April 16, 2024 | https://doi.org/10.1371/journal.pntd.0012127

Schistosome infection among pregnant women in the rural highlands of Madagascar: A cross-sectional study calling for public health interventions in vulnerable populations

Raphäel Rakotozandrindrainy, Rivo Andry Rakotoarivelo, Irina Kislaya, Valentina Marchese, Tahimandranto Rasamoelina, Jeannine Solonirina, Elveric Fesia Ratiaharison, Ravo Razafindrakoto, Nantenaina Matthieu Razafindralava, Njary Rakotozandrindrainy, Mickael Radomanana, Mala Rakoto Andrianarivelo, Philipp Klein, Eva Lorenz, Anna Jaeger, Pytsje T. Hoekstra, Paul L. A. M. Corstjens, Norbert Georg Schwarz, Govert J. van Dam, Jürgen May, Daniela Fusco, on behalf of the freeBILy consortium

PLOS Neglected Tropical Diseases: published April 16, 2024 | https://doi.org/10.1371/journal.pntd.0011766

Modelled impact of Tiny Targets on the distribution and abundance of riverine tsetse

Glyn A. Vale, John W. Hargrove, Andrew Hope, Steve J. Torr

PLOS Neglected Tropical Diseases: published April 16, 2024 | https://doi.org/10.1371/journal.pntd.0011578

Association of liver function and prognosis in patients with severe fever with thrombocytopenia syndrome

Shaoqiu Zhang, Jian Wang, Qun Zhang, Yifan Pan, Zhiyi Zhang, Yu Geng, Bei Jia, Yuanyuan Li, Yali Xiong, Xiaomin Yan, Jie Li, Huali Wang, Chao Wu, Rui Huang

PLOS Neglected Tropical Diseases: published April 16, 2024 | https://doi.org/10.1371/journal.pntd.0012068

Effect of fasting plasma glucose level in severe fever and thrombocytopenia syndrome patients without diabetes

Jun Pan, Zhihao Yang, Wen Xu, Shan Tian, Xiaobo Liu, Chunxia Guo

PLOS Neglected Tropical Diseases: published April 16, 2024 | https://doi.org/10.1371/journal.pntd.0012125

Dengue vector control in high-income, city settings: A scoping review of approaches and methods

Anna Durrance-Bagale, Nirel Hoe, Jane Lai, Jonathan Wee Kent Liew, Hannah Clapham, Natasha Howard

PLOS Neglected Tropical Diseases: published April 17, 2024 | https://doi.org/10.1371/journal.pntd.0012081

The Vicious Worm education tool improves the knowledge of community health workers on Taenia solium cysticercosis in Rwanda

Esther Uwibambe, Anselme Shyaka, Egide Niyotwagira, Justine Mutoniwase, Eric M. Fèvre, Rupert J. Quinnell, Chiara Trevisan

PLOS Neglected Tropical Diseases: published April 17, 2024 | https://doi.org/10.1371/journal.pntd.0012140

Predominance of multidrug-resistant Salmonella Typhi genotype 4.3.1 with low-level ciprofloxacin resistance in Zanzibar

Annette Onken, Sabrina Moyo, Mohammed Khamis Miraji, Jon Bohlin, Msafiri Marijani, Joel Manyahi, Kibwana Omar Kibwana, Fredrik Müller, Pål A. Jenum, Khamis Ali Abeid, Marianne Reimers, Nina Langeland, Kristine Mørch, Bjørn Blomberg

PLOS Neglected Tropical Diseases: published April 17, 2024 | https://doi.org/10.1371/journal.pntd.0012132

Global seroprevalence of Zika virus in asymptomatic individuals: A systematic review

Paola Mariela Saba Villarroel, Rodolphe Hamel, Nuttamonpat Gumpangseth, Sakda Yainoy, Phanit Koomhin, Dorothée Missé, Sineewanlaya Wichit

PLOS Neglected Tropical Diseases: published April 17, 2024 | https://doi.org/10.1371/journal.pntd.0011842

Edge Artificial Intelligence (AI) for real-time automatic quantification of filariasis in mobile microscopy

Lin Lin, Elena Dacal, Nuria Díez, Claudia Carmona, Alexandra Martin Ramirez, Lourdes Barón Argos, David Bermejo-Peláez, Carla Caballero, Daniel Cuadrado, Oscar Darias-Plasencia, Jaime García-Villena, Alexander Bakardjiev, Maria Postigo, Ethan Recalde-Jaramillo, Maria Flores-Chavez, Andrés Santos, María Jesús Ledesma-Carbayo, José M. Rubio, Miguel Luengo-Oroz

PLOS Neglected Tropical Diseases: published April 17, 2024 | https://doi.org/10.1371/journal.pntd.0012117

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