Steep topography and environmental deficiencies, including open sewers and dense vegetation, in an informal settlement in Salvador, Brazil, where chikungunya virus exposure was studied. Travis et al. 2025
Image Credit: Dr. Max Eyre
Viewpoints
Mixing methods: How listening to researchers, healthcare workers, and community members can improve the design of studies testing medical innovations for Neglected Tropical Diseases
Astrid C. Erber, Anthony Ablordey, Adamu Addissie, Evans K. Ahortor, Doris Burtscher, Esther M. Mukooza, Richard Creswell, Ben Lambert, Piero L. Olliaro
PLOS Neglected Tropical Diseases: published September 30, 2025 | https://doi.org/10.1371/journal.pntd.0013547
Policy Platform
MoLEP—Co-creating a Mycobacterium leprae transmission interruption program for the Morogoro region, Tanzania
Tanja Barth-Jaeggi, Guy de Coulon, Issa Garimo, John Msaki, Liberate Mleoh, Riziki Kisonga, Sunil Modali, Shaishav Panchal, Shigela Marco Njebele, Shamez Sunderji, Kihulya Mageda, Peter Steinmann
PLOS Neglected Tropical Diseases: published September 19, 2025 | https://doi.org/10.1371/journal.pntd.0013507
Reviews
Unlocking the blueprint to eliminating neglected tropical diseases: A review of efforts in 50 countries that have eliminated at least 1 NTD
Helmi Hietanen, Lorraine Tsitsi Pfavayi, Francisca Mutapi
PLOS Neglected Tropical Diseases: published September 4, 2025 | https://doi.org/10.1371/journal.pntd.0013424
Orthohantavirus rodent hosts and genotypes in Southern South America: A narrative review
Natalia Ortiz, Juan Diego Pinotti, Verónica Andreo, Raúl Enrique González-Ittig, Cristina Noemí Gardenal
PLOS Neglected Tropical Diseases: published September 9, 2025 | https://doi.org/10.1371/journal.pntd.0013489
Guaroa virus, a forgotten Latin American orthobunyavirus: A narrative review
Carlos Ramiro Silva-Ramos, Patricia V. Aguilar
PLOS Neglected Tropical Diseases: published September 19, 2025 | https://doi.org/10.1371/journal.pntd.0013523
Research Articles
Concurrent chromoblastomycosis and eumycetoma: a unique case of dual neglected tropical fungal diseases in Asia
Wentao Liu, Shuxia Xie, Guoxing Zhu, Shitong Qin, Meirong Li, Songchao Yin, Wei Lai, Chun Lu, Qiaoping Chen, Peiying Feng
PLOS Neglected Tropical Diseases: published September 2, 2025 | https://doi.org/10.1371/journal.pntd.0013484
PANoptosis-mediated mechanisms underlying AST elevation in Talaromyces marneffei infection
Wudi Wei, Baili Zhan, Lixiang Chen, Gang Wang, Xiuli Bao, Xiaotao He, Meng Zhang, Xiaoting Xie, Weihong Huang, Zhiman Xie, Junjun Jiang, Hao Liang, Li Ye
PLOS Neglected Tropical Diseases: published September 2, 2025 | https://doi.org/10.1371/journal.pntd.0013443
Tracking the urban spread of Usutu virus in southern France: Detection across biological and environmental matrices
Rachel Beaubaton, Justine Revel, Laetitia Pigeyre, Karine Bollore, Alexandre Lepeule, Julien Mocq, Christophe de Franceschi, Julien Pradel, Yvon Perrin, David Gomis, Marie Ducousso, Laurie Virolle, Baptiste Chenet, Guillaume Castel, Anne Charmantier, Nathalie Charbonnel, Guillaume Lacour, Olivier Courot, Antoine Mignotte, Yannick Simonin
PLOS Neglected Tropical Diseases: published September 2, 2025 | https://doi.org/10.1371/journal.pntd.0013506
Future of snakebite risk in India: Consequence of climate change and the shifting habitats of the big four species in next five decades
Imon Abedin, Hey-Eun Kang, Hemanta Saikia, Won-Kyo Jung, Hyun-Woo Kim, Shantanu Kundu
PLOS Neglected Tropical Diseases: published September 2, 2025 | https://doi.org/10.1371/journal.pntd.0013464
From injury to outcome: A mixed-methods study of animal-related injuries in a rural district of Tanzania
Gimbo Hyuha, Notikela Nyamle, Manase Kilonzi, Paul Malaba Makoye, Castory Sananga Chuwa, Beatrice Aiko, Nathanael Sirili
PLOS Neglected Tropical Diseases: published September 2, 2025 | https://doi.org/10.1371/journal.pntd.0013494
Natural infection of filarioid nematodes in mosquitoes: An approach to neglected disease xenosurveillance and prevention in intercontinental human transit areas in Darién
Eddier Rivera, Anyi Tuñon, Mileyka Santos, Luisa Collado-Mariscal, Marlin González, Anayansi Valderrama
PLOS Neglected Tropical Diseases: published September 3, 2025 | https://doi.org/10.1371/journal.pntd.0013395
Stocking African catfish in Lake Victoria provides effective biocontrol of snail vectors of Schistosoma mansoni
Roland Proud, Fiona Allan, Andrew Whiston, Robert Kayanda, Safari Kinung’hi, Teckla Angelo, Yasinta D. Sylivester, Hillary D. J. Mrosso, Benedicto B. Kashindye, Mboni Elison, Martin J. Cox, Yang Yang, Andrew Chamberlin, Ian L. Boyd, David J. Civitello, Giulio A. De Leo, Andrew S. Brierley
PLOS Neglected Tropical Diseases: published September 3, 2025 | https://doi.org/10.1371/journal.pntd.0013490
The impact of temperature on canine Chagas disease transmission risk: A modeling study
Edem Fiatsonu, Sina Mokhtar, Martial L. Ndeffo-Mbah
PLOS Neglected Tropical Diseases: published September 3, 2025 | https://doi.org/10.1371/journal.pntd.0013498
The relationship between expelled eggs, morbidity and age in a Schistosoma mansoni endemic setting in Uganda: Implications for current elimination policies
Rivka M. Lim, Ruhi Lahoti, Jessica Clark, Moses Arinaitwe, Victor Anguajibi, Sergi Alonso, Andrina Nankasi, Fred Besigye, Alon Atuhaire, Amy B. Pedersen, Joanne P. Webster, Poppy H. L. Lamberton
PLOS Neglected Tropical Diseases: published September 3, 2025 | https://doi.org/10.1371/journal.pntd.0012750
Extreme weather events and dengue in Southeast Asia: A regionally-representative analysis of 291 locations from 1998 to 2021
Sophearen Ith, Xerxes Seposo, Vitou Phy, Kraichat Tantrakarnapa, Geminn Louis C. Apostol, Pandji Wibawa Dhewantara, Rozita Hod, Mohd Rohaizat Hassan, Hidayatulfathi Othman, Mazrura Sahani, Jue Tao Lim, Ha Hong Nhung, Nguyen Hai Tuan, Ngu Duy Nghia, Taichiro Takemura, Inthavong Nouhak, Paul L. C. Chua, Alex R. Cook, Felipe J. Colón-González, Masahiro Hashizume
PLOS Neglected Tropical Diseases: published September 4, 2025 | https://doi.org/10.1371/journal.pntd.0012649
Impact of Clonorchis sinensis infection on long-term survival after curative resection for hepatocellular carcinoma: A multicenter cohort study
Shuang Shen, Xin Qiu, Guodong Yang, Yi Peng, Haojie Yang, Jindu Li, Jiayin Qin, Huijie Tang, Huaiyue Liang, Wenyang Zhang, Hai Huang, Ze Su, Bangde Xiang
PLOS Neglected Tropical Diseases: published September 4, 2025 | https://doi.org/10.1371/journal.pntd.0013441
Kinome analysis of Madurella mycetomatis identified kinases in the cell wall integrity pathway as novel potential therapeutic drug targets in eumycetoma caused by Madurella mycetomatis
Mickey Konings, Nikolaos Strepis, Ri-Ichiroh Manabe, Akira Hasegawa, Somdatta Chaudhari, Saskia du Pré, Marij Schippers, Michihira Tagami, Jingyi Ma, Yasushi Okazaki, Matthew Todd, Bernhard Biersack, Vijay Masand, Annelies Verbon, Takeya Kasukawa, Imad Abugessaisa, Wendy W. J. van de Sande
PLOS Neglected Tropical Diseases: published September 4, 2025 | https://doi.org/10.1371/journal.pntd.0013482
BFD2 mediates inflammation, apoptosis, and pre-anxiety-like behaviors induced by acute Toxoplasma gondii infection
Xiaocheng Zhang, Tanzhen Xu, Jinjin Zhu, Hui Peng, Zixin Wei, Lijun Cui, Qingqiu Zuo, Hua Liu, Yuan Hu, Jianping Cao
PLOS Neglected Tropical Diseases: published September 4, 2025 | https://doi.org/10.1371/journal.pntd.0013428
Chromoblastomycosis and phaeohyphomycotic abscess-associated hospitalizations, United States, 2016–2021
Dallas J. Smith, Kaitlin Benedict, Shawn R. Lockhart, Sanjay G. Revankar
PLOS Neglected Tropical Diseases: published September 4, 2025 | https://doi.org/10.1371/journal.pntd.0013499
Surveillance of tick-borne viruses in the border regions of the Tumen River Basin: Co-circulation in ticks and livestock
Zhe Liu, Shengwei Ji, Qiaocheng Chang, Jinqi Wang, Eloiza May Galon, Ying Xu, Guolu Yin, Jixu Li, Xu Gao, Wannian Tian, Zhenzhen Han, Chenghui Li, Zhiqiang Xu, Rui Du, Shujiang Xue
PLOS Neglected Tropical Diseases: published September 4, 2025 | https://doi.org/10.1371/journal.pntd.0013500
Socio-psychological determinants of scabies contact notification among Dutch students: A qualitative study
Sunia B. Somra, Hélène A.C.M. Voeten, Inge Lewis - van Disseldorp, Fraukje E.F. Mevissen
PLOS Neglected Tropical Diseases: published September 4, 2025 | https://doi.org/10.1371/journal.pntd.0013471
Extracellular microbes are required for mosquito development even in the presence of Wolbachia
Javier Serrato-Salas, Yanouk Epelboin, Danai Bemplidaki, Ivan Roger, Mathilde Gendrin
PLOS Neglected Tropical Diseases: published September 5, 2025 | https://doi.org/10.1371/journal.pntd.0013481
Community deployment of metofluthrin emanators to control indoor Aedes aegypti: Efficacy results from a crossover trial in Yucatan, Mexico
Azael Che-Mendoza, Guillermo Guillermo-May, Oscar D. Kirstein, Aylin Chi-Ku, Norma Pavía-Ruz, Anuar Medina-Barreiro, Gabriela González-Olvera, Gregor Devine, Gonzalo Vazquez-Prokopec, Pablo Manrique-Saide
PLOS Neglected Tropical Diseases: published September 5, 2025 | https://doi.org/10.1371/journal.pntd.0012883
Taxonomic, molecular and ecological approach reveals high diversity of vector sand flies, varied blood source supply and a high detection rate of Leishmania DNA in Colombian Amazon region
Katerine Caviedes-Triana, Daniela Duque-Granda, Gloria Cadavid-Restrepo, Claudia X. Moreno-Herrera, Rafael Vivero-Gomez
PLOS Neglected Tropical Diseases: published September 5, 2025 | https://doi.org/10.1371/journal.pntd.0013445
Spatio-temporal analysis of the distribution and co-circulation of dengue, chikungunya, and Zika in Medellín, Colombia, from 2013 to 2021
Jorge E. Salazar Flórez, Berta N. Restrepo, Laís Picinini Freitas, Mabel Carabali, Gloria I. Jaramillo Ramírez, Cesar Garcia Balaguera, Brayan S. Avila Monsalve, Kate Zinszer
PLOS Neglected Tropical Diseases: published September 5, 2025 | https://doi.org/10.1371/journal.pntd.0013470
Topography and environmental deficiencies are associated with chikungunya virus exposure in urban informal settlements in Salvador, Brazil
Catherine Tamera Travis, Hernán D. Argibay, Maysa Pellizzaro, Daiana de Oliveira, Roberta Santana, Fabiana Almerinda G. Palma, Ricardo Lustosa, Juliet Oliveira Santana, Fábio Neves Souza, Yeimi Alexandra Alzate López, Mitermayer G. Reis, Albert I. Ko, Peter J. Diggle, Guilherme S. Ribeiro, Michael Begon, Federico Costa, Hussein Khalil, Max T. Eyre
PLOS Neglected Tropical Diseases: published September 5, 2025 | https://doi.org/10.1371/journal.pntd.0013477
Analysis of predictors of rabies-positive biting animals in Cambodia using spatio-temporal Bayesian regression modelling
Jerome N. Baron, Yik Sik Peng, Beatriz Martínez-López, Sowath Ly, Philippe Dussart, Véronique Chevalier
PLOS Neglected Tropical Diseases: published September 5, 2025 | https://doi.org/10.1371/journal.pntd.0013478
Risk factors and leprosy incidence among contacts in Bangladesh: A multilevel analysis
Unnati Rani Saha, Abu Sufian Chowdhury, Johan Chandra Roy, Khorshed Alam, Daan Nieboer, Renate Verbiest-Richardus, Annemieke Geluk, Jan Hendrik Richardus
PLOS Neglected Tropical Diseases: published September 5, 2025 | https://doi.org/10.1371/journal.pntd.0013465
Assessing the impact of tungiasis on children’s quality of life in Kenya
Lynne Elson, Berrick Otieno, Abneel K. Matharu, Naomi Riithi, Esther Jebor Chongwo, Francis Mutebi, Hermann Feldmeier, Jürgen Krücken, Ulrike Fillinger, Amina Abubakar
PLOS Neglected Tropical Diseases: published September 8, 2025 | https://doi.org/10.1371/journal.pntd.0012606
Impact of diabetes mellitus on adenolymphangitis episodes in patients with filarial lymphedema—Towards an integrated care approach
Nikita Kubal, Sowmiya Manavalan, Vijayakumar Balakrishnan, Nileshkumar Elangovan, Danapriyaa Dharmalingam, Vijesh Sreedhar Kuttiatt
PLOS Neglected Tropical Diseases: published September 8, 2025 | https://doi.org/10.1371/journal.pntd.0013486
Territorial and gender-linked risk factors for Buruli ulcer in Southern Benin: A case-control study using geographic and behavioral surveying
Harvey Johnson, Alexandra Boccarossa, Esai Anagonou, Télésphore Brou, Perin Catraye, Sébastien Fleuret, Estelle Marion, Matthieu Eveillard
PLOS Neglected Tropical Diseases: published September 8, 2025 | https://doi.org/10.1371/journal.pntd.0013509
Factors associated with health worker adoption of facial and environmental hygiene promotion in the ‘SAFE strategy’ for trachoma elimination in Western Province, Zambia
Martha Kasongo, Choolwe Jacobs, Adam Silumbwe, Patricia Maritim, Joseph Mumba Zulu, Hikabasa Halwindi
PLOS Neglected Tropical Diseases: published September 8, 2025 | https://doi.org/10.1371/journal.pntd.0013483
Geostatistical analysis to guide treatment decisions for soil-transmitted helminthiasis control in Uganda
Bryan O. Nyawanda, Kristin M. Sullivan, Benjamin Tinkitina, Prudence Beinamaryo, Betty Nabatte, Hilda Kyarisiima, Alfred Mubangizi, Paul M. Emerson, Jürg Utzinger, Penelope Vounatsou
PLOS Neglected Tropical Diseases: published September 8, 2025 | https://doi.org/10.1371/journal.pntd.0013467
Interstitial pneumonia via the oropharyngeal route of infection with Encephalitozoon cuniculi
Mariana Souza Santos, Rodrigo A. da Silva, Lucas Nunes de Souza, Nicolli R. Victorino, Rayane C.B. Pereira, José Guilherme Xavier, Ronalda da Silva Araújo, Elizabeth C. Pérez, Anuska M. Alvares-Saraiva, Maria Anete Lallo
PLOS Neglected Tropical Diseases: published September 8, 2025 | https://doi.org/10.1371/journal.pntd.0012130
People-centered strategies to mobilize people living with disabilities due to Neglected Tropical Diseases (PD-NTDs) to influence policy and programs: A mixed-methods study in Côte d’Ivoire
Julien Aké, Eunheh Koh, Tiembre Issiaka, Boko-Koiadia Adjoua N’Groma Nadège, Lorou Bi Maxime, Maneesh Phillip, Konan Anne Cécille, Rie Yotsu
PLOS Neglected Tropical Diseases: published September 8, 2025 | https://doi.org/10.1371/journal.pntd.0013485
Community-directed treatment with ivermectin in Maridi, South Sudan: Impact of an onchocerciasis awareness campaign and bi-annual treatment on therapeutic coverage
Joseph Nelson Siewe Fodjo, Moses Okwii, Stephen Raimon Jada, Amber Hadermann, Jacopo Rovarini, Luis-Jorge Amaral, Rogers Nditanchou, Yak Yak Bol, Makoy Y. Logora, Jane Y. Carter, Johan Willems, Robert Colebunders
PLOS Neglected Tropical Diseases: published September 8, 2025 | https://doi.org/10.1371/journal.pntd.0013493
Clinical, virological, and antibody profiles of overlapping dengue and chikungunya virus infections in children from southern Colombia
Daniela Polanía-Espinosa, Sebastián Castro-Trujillo, Carlos F. Narváez
PLOS Neglected Tropical Diseases: published September 8, 2025 | https://doi.org/10.1371/journal.pntd.0013260
The prevalence of trachoma, ocular Chlamydia trachomatis infection and anti-Pgp3 antibodies in Choiseul Province, Solomon Islands
Clare E. F. Dyer, Carleigh S. Cowling, Oliver Sokana, Lazarus Neko, Nemia Bainivalu, Freda Pitakaka, Anasaini Cama, Mitchel Starr, Emma M. Harding-Esch, Cristina Jimenez, Ana Bakhtiari, Sarah Boyd, Sara Webster, Anthony W. Solomon, John M. Kaldor, Susana Vaz Nery
PLOS Neglected Tropical Diseases: published September 8, 2025 | https://doi.org/10.1371/journal.pntd.0013381
Diversity of Salmonella enterica isolates from urban river and sewage water in Blantyre, Malawi
Jonathan Rigby, Catherine N. Wilson, Allan Zuza, Yohane Diness, Charity Mkwanda, Katalina Tonthola, Oscar Kanjerwa, Chifundo Salifu, Oliver Pearse, Chisomo Msefula, Blanca M. Perez-Sepulveda, Jay C.D. Hinton, Satheesh Nair, Nicola Elviss, Mathew A. Beale, Patrick Musicha, Nicholas A. Feasey
PLOS Neglected Tropical Diseases: published September 9, 2025 | https://doi.org/10.1371/journal.pntd.0012413
CLASV: Rapid Lassa virus lineage assignment with random forest
Richard Olumide Daodu, Ebenezer Awotoro, Jens-Uwe Ulrich, Denise Kühnert
PLOS Neglected Tropical Diseases: published September 9, 2025 | https://doi.org/10.1371/journal.pntd.0013512
Usability and quality evaluation of the World Health Organization SkinNTDs app among frontline health workers in Cameroon: A mixed methods study
Henri Claude Moungui, Paul Tonkoung Iyawa, Hugues Nana-Djeunga, Jose Antonio Ruiz-Postigo, Carme Carrion
PLOS Neglected Tropical Diseases: published September 10, 2025 | https://doi.org/10.1371/journal.pntd.0013461
Paratyphoid fever and the genomics of Salmonella enterica serovar Paratyphi A in Taiwan
Ying-Shu Liao, Yu-Ping Hong, Bo-Han Chen, You-Wun Wan, Ru-Hsiou Teng, Shiu-Yun Liang, Hsiao Lun Wei, Jui-Hsien Chang, Ming-Hao Yang, Chi-Sen Tsao, Chien-Shun Chiou
PLOS Neglected Tropical Diseases: published September 11, 2025 | https://doi.org/10.1371/journal.pntd.0013048
Clinical features and mortality risk factors in non-HIV elderly patients with cryptococcal meningitis: A retrospective cohort study from 2013 to 2022
Xiaofeng Xu, Xiaohong Su, Weipeng Li, Li Xu, Dongcheng Li, Kai Dai, Junyu Liu, Jia Liu, Fuhua Peng, Ying Jiang
PLOS Neglected Tropical Diseases: published September 11, 2025 | https://doi.org/10.1371/journal.pntd.0013521
Early events in dengue virus infection inducing cytokine storm: The dynamic interplay of pattern-recognition receptors, inflammasome activation, and biphasic NF-κB and STAT1-dependent inflammatory responses in human mononuclear phagocytes
Juan Felipe Valdés-López, Yordi Sebastián Tamayo-Molina, Geysson J. Fernandez, Lady Johana Hernández-Sarmiento, Paula A. Velilla, Silvio Urcuqui-Inchima
PLOS Neglected Tropical Diseases: published September 11, 2025 | https://doi.org/10.1371/journal.pntd.0013366
Glycosomal ABC transporter 3 (GAT3) deletion enhances the oxidative stress responses and reduces the infectivity of Trypanosoma cruzi
Davi Alvarenga Lima, Héllida Marina Costa-Silva, Karen Stephanie Sebe Albergaria, Juliana Martins Ribeiro, Daniela de Melo Resende, Bruno Alves Santarossa, Daniel Barbosa Liarte, Simone Guedes Calderano, Silvane Maria Fonseca Murta
PLOS Neglected Tropical Diseases: published September 11, 2025 | https://doi.org/10.1371/journal.pntd.0013479
Molecular docking to homology models of human and Trypanosoma brucei ERK8 that identified ortholog-specific inhibitors
Matthew Merski, Zachary B. Mackey
PLOS Neglected Tropical Diseases: published September 12, 2025 | https://doi.org/10.1371/journal.pntd.0013487
Development and proof-of-concept evaluation for a low resource compatible Chikungunya virus diagnostic
Rickyle Balea, Alberto A. Amarilla, Jody Hobson-Peters, Joanne Macdonald, Andreas Suhrbier, Vasilli M. Kasimov, Daniel Watterson, Nina M. Pollak, David J. McMillan
PLOS Neglected Tropical Diseases: published September 12, 2025 | https://doi.org/10.1371/journal.pntd.0012352
Cryptosporidium parvum protease INS6 plays an important role in parasite proliferation and pathogenicity
Wei He, Zuwei Yang, Jing Wang, Fuxian Yang, Na Li, Rui Xu, Songrong Zeng, Lihua Xiao, Yaoyu Feng, Yaqiong Guo
PLOS Neglected Tropical Diseases: published September 12, 2025 | https://doi.org/10.1371/journal.pntd.0013532
Computational and experimental exploration of statin and statin-like compounds as potential treatment of schistosomiasis
Kehinde F. Paul-Odeniran, Paul O. Odeniran, Cécile Häberli, Jennifer Keiser, Charles A. Laughton
PLOS Neglected Tropical Diseases: published September 12, 2025 | https://doi.org/10.1371/journal.pntd.0013524
Whole genome sequencing of Yersinia pestis isolates from Central Asian natural plague foci revealed the role of adaptation to different hosts and environmental conditions in shaping specific genotypes
Aigul A. Abdirassilova, Duman T. Yessimseit, Altynai K. Kassenova, Beck Z. Abdeliyev, Zauresh B. Zhumadilova, Gulnara Zh. Tokmurziyeva, Galina G. Kovaleva, Ziyat Zh. Abdel, Tatiyana V. Meka-Mechenko, Saule K. Umarova, Elmira Zh. Begimbayeva, Sanzhar D. Agzam, Vladimir L. Motin, Oleg N. Reva, Altyn K. Rysbekova
PLOS Neglected Tropical Diseases: published September 12, 2025 | https://doi.org/10.1371/journal.pntd.0013533
Roles of tick-cofeeding hedgehogs in the natural transmission of spotted fever group Rickettsia
Haiming Yi, Weilin Huang, Changqiang Zhu, Yixin Ge, Xijing Yang, Sunjie Yang, Chuchu Ye, Junhu Wang, Qiong Chen, Yingqing Mao, Hongming Wang, Lele Ai, Wei Guo, Chao Chen, Weilong Tan, Yuexi Li, Yong Qi
PLOS Neglected Tropical Diseases: published September 15, 2025 | https://doi.org/10.1371/journal.pntd.0013224
Exploring the status of brucellosis in pregnant women presented with febrile illness at different healthcare facilities of Vehari and Lodhran zones of Pakistan
Syed Muhammad Tauseef Shafqat, Mian Muhammad Awais, Ulas Acaroz, Masood Akhtar, Abdul Sammad Ali Khan Shirwany, Imran Rasool, Naseer Ali Shah
PLOS Neglected Tropical Diseases: published September 15, 2025 | https://doi.org/10.1371/journal.pntd.0013525
Chikungunya virus in Thailand (2020–2023): Epidemiology, clinical features, and genomic insights
Sarawut Khongwichit, Watchaporn Chuchaona, Sumeth Korkong, Lakkhana Wongsrisang, Thanunrat Thongmee, Yong Poovorawan
PLOS Neglected Tropical Diseases: published September 15, 2025 | https://doi.org/10.1371/journal.pntd.0013548
Fixed-dose ivermectin for Mass Drug Administration: Is it time to leave the dose pole behind? Insights from an Individual Participant Data Meta-Analysis
Adriana Echazu, Daniela Bonanno, Pedro Emanuel Fleitas, Julie Jacobson, Gabriela Matamoros, Charles Mwandawiro, Wendemagegn Enbiale, Áuria de Jesus, Alan Brooks, Alejandro Javier Krolewiecki
PLOS Neglected Tropical Diseases: published September 15, 2025 | https://doi.org/10.1371/journal.pntd.0013059
Unexplained subcutaneous swelling: Keep echinococcosis in mind! Report of two primary extrahepatic subcutaneous echinococcosis cases and literature review
Louis Bohard, Eléonore Brumpt, Noémie Tissot, Marie Lacoste, Olivia Chapuis, Sophie Felix, Jenny Knapp, Carole Hartmann-Gouvenot, Yannick Jeffredo, Frederic Grenouillet, Damien Montange, Anne-Pauline Bellanger, Catherine Chirouze, Solange Bresson-Hadni
PLOS Neglected Tropical Diseases: published September 15, 2025 | https://doi.org/10.1371/journal.pntd.0013511
Disability and quality of life assessment using WHODAS-12 items 2.0 and EQ-5D-5L in a rural area endemic for loiasis in the Republic of Congo: A population-based cross-sectional study (the MorLo project)
Marlhand C. Hemilembolo, Jérémy T. Campillo, Valentin Dupasquier, Elodie Lebredonchel, Samuel Beneteau, Ludovic G. Rancé, Glorifié Madoulou Moulabou, Ange Clauvel Niama, Richard R. Bileckot, Sébastien D. S. Pion, Michel Boussinesq, François Missamou, Cédric B. Chesnais
PLOS Neglected Tropical Diseases: published September 15, 2025 | https://doi.org/10.1371/journal.pntd.0013491
Differentiating proven progressive disseminated histoplasmosis from other diagnoses in hospitalized persons with HIV and suspected progressive disseminated histoplasmosis: Findings from a clinical and demographic study in Mexico
Maria Dolores Niembro-Ortega, Areli Martinez-Gamboa, Antonio Olivas-Martinez, Brenda Crabtree-Ramirez, Janeth Santiago-Cruz, Andrea Rangel-Cordero, Pedro Torres-Gonzalez, Armando Gamboa-Dominguez, Victor Hugo Lozano-Fernandez, Victor Hugo Ahumada-Topete, Pedro Martinez-Ayala, Marisol Manriquez-Reyes, Juan Pablo Ramirez-Hinojosa, Patricia Rodriguez-Zulueta, Jesus Ruiz-Quiñones, Christian Hernandez-Leon, Norma Erendira Rivera-Martinez, Alberto Chaparro-Sanchez, Jaime Andrade-Villanueva, Luz Alicia Gonzalez-Hernandez, Sofia Cruz-Martinez, Oscar Flores-Barrientos, Jesus Enrique Gaytan-Martinez, Axel Cervantes Sanchez, Nancy Guadalupe Velazquez-Zavala, Maria del Rocio Reyes-Montes, Esperanza Duarte Escalante, Maria Guadalupe Frias De Leon, Jose Antonio Ramirez, Maria Lucia Taylor, Jose Sifuentes-Osornio, Alfredo Ponce de Leon
PLOS Neglected Tropical Diseases: published September 17, 2025 | https://doi.org/10.1371/journal.pntd.0013527
Exploration of tongue dorsum sampling to support clinical diagnosis of leprosy patients in the Comoros: A cross-sectional study
Lena Krausser, Maren Van Nieuwenhove, Nissad Attoumani, Silahi H. Grillone, Magalie Van Dyck-Lippens, Leen Rigouts, Abdallah Baco, Wirdane Abdou, Aboubacar Mzembaba, Epco Hasker, Younoussa Assoumani, Bouke C. de Jong, Sofie M. Braet
PLOS Neglected Tropical Diseases: published September 17, 2025 | https://doi.org/10.1371/journal.pntd.0013541
Assessing the need to implement mass drug administration against Wuchereria bancrofti infection using both human serology and xenomonitoring in the urban conurbation of Monrovia, Liberia
Benjamin G. Koudou, Rogers Nditanchou, Firmain N. Yokoly, Abakar Gankpala, Karsor K. Kollie, David Molyneux, Philip Downs, Ruth Dixon
PLOS Neglected Tropical Diseases: published September 18, 2025 | https://doi.org/10.1371/journal.pntd.0013446
Climate change, urbanisation and transmission potential: Aedes aegypti mosquito projections forecast future arboviral disease hotspots in Brazil
Katherine Heath, Lincoln Muniz Alves, Michael B. Bonsall
PLOS Neglected Tropical Diseases: published September 18, 2025 | https://doi.org/10.1371/journal.pntd.0013415
Scrub typhus in Nan province (Thailand): Seventeen years of data to understand the impact of land cover change
Nolwenn Blache, Karine Chalvet-Monfray, Rawadee Kumlert, Soawapak Hinjoy, Serge Morand
PLOS Neglected Tropical Diseases: published September 18, 2025 | https://doi.org/10.1371/journal.pntd.0013552
Interleukin-10 limits immune-mediated pathology in chronic subclinical plasmodial infection
Leandro de Souza Silva, Brian G. Monks, Catherine S. Forconi, Juliet N. Crabtree, Nelsy De Paula Tamburro, Evelyn A. Kurt-Jones, Ricardo T. Gazzinelli, Katherine A. Fitzgerald, Douglas T. Golenbock
PLOS Neglected Tropical Diseases: published September 19, 2025 | https://doi.org/10.1371/journal.pntd.0013554
Detection of potential transmission foci of lymphatic filariasis using molecular xenomonitoring in Huahine, French Polynesia
Reva Lannuzel, Tanagra Lambert, Farah Deen, Hmeniko Tourancheau, Jérôme Marie, Michel A. Cheong Sang, Manfred Mervin, Benoit Stoll, Hervé C. Bossin, Françoise Mathieu-Daudé
PLOS Neglected Tropical Diseases: published September 19, 2025 | https://doi.org/10.1371/journal.pntd.0013492
Topical AuNPs-Cys-Sm29 gel modulates the course of lesion development in experimental cutaneous leishmaniasis
Sayonara de M. Viana, Luciana Cardoso, Pedro B. Borba, Lucas P. Carvalho, Juvana Moreira, Fabio Mambelli, Sergio C. Oliveira, Edgar M. Carvalho, Camila I. de Oliveira
PLOS Neglected Tropical Diseases: published September 22, 2025 | https://doi.org/10.1371/journal.pntd.0013510
Etiological spectrum and diagnostic features of lymphadenopathy in People Living with HIV in French Guiana: A 17-years multicenter retrospective case series
Morgane Bourne-Watrin, Ugo Françoise, Sophie Alexandra Baron, Antoine A. Adenis, Dufens Pierre Louis, Loïc Epelboin, Mathieu Nacher, Félix Djossou, Kinan Drak Alsibai, Pierre Couppié
PLOS Neglected Tropical Diseases: published September 22, 2025 | https://doi.org/10.1371/journal.pntd.0013558
Endemicity, disability and neglect: Leprosy in Colombia 2007–2020
Carlos Arango-Úsuga, Jesús Ochoa, Doracelly Hincapié-Palacio, Alba León
PLOS Neglected Tropical Diseases: published September 22, 2025 | https://doi.org/10.1371/journal.pntd.0013514
Antibody responses to Japanese encephalitis virus and dengue virus serotype 2 in children from an orthoflavivirus endemic region after IMOJEV vaccination
Fatima Ericka S. Vista, Leslie Michelle M. Dalmacio, Pauline R. Solis, Cecilia Nelia C. Maramba-Lazarte, Diane M. Lang, Alan L. Rothman, Sheriah Laine M. de Paz-Silava
PLOS Neglected Tropical Diseases: published September 22, 2025 | https://doi.org/10.1371/journal.pntd.0013550
Population pharmacokinetic-pharmacodynamic analysis of benznidazole monotherapy and combination therapy with fosravuconazole in chronic Chagas disease (BENDITA)
Frauke Assmus, Cintia Cruz, James A. Watson, Nicholas J. White, Ayorinde Adehin, Richard M. Hoglund, Bethania Blum de Oliveira, Fabiana Barreira, Ivan Scandale, Joel Tarning
PLOS Neglected Tropical Diseases: published September 22, 2025 | https://doi.org/10.1371/journal.pntd.0013522
Impact of temperature and imported cases on the spread and control of dengue fever: Case study of 2019 dengue fever epidemic in Guangzhou and Jinghong cities, China
Yue Zhang, Xianghong Zhang, Kaifa Wang
PLOS Neglected Tropical Diseases: published September 22, 2025 | https://doi.org/10.1371/journal.pntd.0013472
Anti-inflammatory cytokine profile and Jarisch-Herxheimer reaction in Leptospirosis patients: A prospective case-series study in New Caledonia
Julie Cagliero, Anne Loarec, Julien Lebon, François Baur, Patrick Lefevre, Emilie Follenfant, Cyrille Goarant, Damaris Ukeiwe, Julien Colot, Sylvie Tardieu, Catherine Werts, Cécile Cazorla
PLOS Neglected Tropical Diseases: published September 23, 2025 | https://doi.org/10.1371/journal.pntd.0013189
Optimizing the implementation of case-area targeted interventions during cholera outbreaks with context-specific delivery mechanisms
Jessica Dunoyer, Ruwan Ratnayake, Sandy Moore, Gregory Bulit, Samuel Beaulieu, Christophe Valingot, Pierre-Yves Oger, Bertrand Sudre, Daniele Lantagne, Nicola Desmond
PLOS Neglected Tropical Diseases: published September 23, 2025 | https://doi.org/10.1371/journal.pntd.0013534
Identifying hotspots of S. haematobium infection following praziquantel treatment during multiple annual mass drug administration campaigns in Zimbabwe
Takafira Mduluza, Grace Zdesenko, Paradzayi Tagwireyi, Caitlin M. Jones, Francisca Mutapi
PLOS Neglected Tropical Diseases: published September 24, 2025 | https://doi.org/10.1371/journal.pntd.0013546
Proteomic-based identification of novel EV-derived protein antibodies biomarkers for melioidosis diagnosis
Nini Luo, Jun Tan, Xuemiao Li, Yanshuang Wang, Ting Zhang, Chen Chen, Lin Liu, Xinyi Song, Hua Pei, Bo Wang, Qi Li, Shen Tian, Nan Zhang, Wei Cheng, Qianfeng Xia
PLOS Neglected Tropical Diseases: published September 24, 2025 | https://doi.org/10.1371/journal.pntd.0013543
A multifaceted molecular approach to surveillance of leishmaniasis: Identification of sand fly species, Leishmania parasites, and blood meal sources using high-resolution melting analysis
Liora Studentsky, Fouad Akad, Debora Diaz, Irina Ben Avi, Shirly Lea Elbaz, Tamar Grossman, Maya Davidovich-Cohen, Oscar David Kirstein, Laor Orshan, Gad Baneth
PLOS Neglected Tropical Diseases: published September 24, 2025 | https://doi.org/10.1371/journal.pntd.0013412
Comparing diagnostic methods for historical arbovirus outbreaks: Insights from 19th century "dengue" epidemics
Timothee Bonifay, Mathieu Nacher, Clémence Bonnefoy, Benjamin Rossi, Edouard Hallet, Philippe Abboud, Guillaume Bellaud, Nathalie Dournon, Aurélia Henn, Adrien Lemaignen, Liem Binh Luong Nguyen, Diane Sanderink, Gaelle Walter, Alexandre Bleibtreu, Loïc Epelboin
PLOS Neglected Tropical Diseases: published September 26, 2025 | https://doi.org/10.1371/journal.pntd.0013551
Drivers of rabies virus spillover risk from vampire bats to livestock in Colombia
Paige Van de Vuurst, Cassidy Rist, Tatiana Medina-Rodriguez, Andres Felipe Osejo-Varona, Diego Soler-Tovar, Luis E. Escobar
PLOS Neglected Tropical Diseases: published September 26, 2025 | https://doi.org/10.1371/journal.pntd.0013508
Landscape-scale analysis of raccoon rabies surveillance reveals different drivers of disease dynamics across latitude
Matthew Michalska-Smith, Meggan E. Craft, Amy J. Davis, Amy T. Gilbert, Richard B. Chipman, Jordona Kirby, Kathleen M. Nelson, Xiaoyue Ma, Ryan Wallace, Grace Miller, Kim M. Pepin
PLOS Neglected Tropical Diseases: published September 26, 2025 | https://doi.org/10.1371/journal.pntd.0013581
Hematological diseases-related mucormycosis: A retrospective single center study
Yu Cui, Rui Zhao, Ruihua Mi, Lin Chen, Lin Wang, Dongbei Li, Cheng Cheng, Mengjuan Li, Xudong Wei
PLOS Neglected Tropical Diseases: published September 26, 2025 | https://doi.org/10.1371/journal.pntd.0013531
Leptospirosis in Campinas, Brazil: The interplay between drainage, impermeable areas, and social vulnerability
Thiago Salomão de Azevedo, Shahista Nisa, Stuart Littlejohn, Renata L. Muylaert
PLOS Neglected Tropical Diseases: published September 29, 2025 | https://doi.org/10.1371/journal.pntd.0013560
A district-level ensemble model to enhance dengue prediction and control for the Mekong Delta Region of Vietnam
Wala Draidi Areed, Thi Thanh Thao Nguyen, Kien Quoc Do, Thinh Nguyen, Vinh Bui, Elisabeth Nelson, Joshua L. Warren, Quang-Van Doan, Nam Vu Sinh, Nicholas John Osborne, Russell Richards, Nu Quy Linh Tran, Hong Le, Tuan Pham, Trinh Manh Hung, Son Nghiem, Hai Phung, Cordia Chu, Robert Dubrow, Daniel M. Weinberger, Dung Phung
PLOS Neglected Tropical Diseases: published September 29, 2025 | https://doi.org/10.1371/journal.pntd.0013571
Passive surveillance of human African trypanosomiasis in the Democratic Republic of the Congo: clinical presentation and prospective evaluation of rapid diagnostic and reference laboratory test accuracy
Jacquies Makabuza, Ipos Ngay Lukusa, Crispin Lumbala, Erick Mwamba Miaka, Pathou Nganzobo, Alain Fukinsia, Jean Kwete, Nicolas Bebronne, Philippe Büscher, Dieudonné Mumba Ngoyi, Veerle Lejon
PLOS Neglected Tropical Diseases: published September 29, 2025 | https://doi.org/10.1371/journal.pntd.0013045
Molecular epidemiology of panton valentine leukocidin-producing Staphylococcus aureus infections, Djibouti, 2018–2023
Maxime Danjean, Virginie Courbin, Aurore Ho, Aurore Bousquet, Christophe Rodriguez, Hervé Jacquier, Paul-Louis Woerther
PLOS Neglected Tropical Diseases: published September 30, 2025 | https://doi.org/10.1371/journal.pntd.0013544
Knowledge, attitudes, and practices on anthrax in selected game management areas in Zambia
Exillia Kabbudula, Laila Gondwe, Chitwambi Makungu, Mtui-Malamsha N. Jesse, Kezzy Besa, Suwilanji S. Sichone, Noanga Mebelo, Mwila Kayula, Geoffrey Mainda, Fredrick M. Kivaria, Charles Bebay, Baba Soumare, Suze P. Filippini, Chisoni Mumba
PLOS Neglected Tropical Diseases: published September 30, 2025 | https://doi.org/10.1371/journal.pntd.0013592
Circulating Angiopoietin-like proteins in Strongyloides Stercoralis infection and reversal following treatment
Anuradha Rajamanickam, Saravanan Munisankar, Subash Babu
PLOS Neglected Tropical Diseases: published September 30, 2025 | https://doi.org/10.1371/journal.pntd.0013559
Spatial distribution patterns and risk factors of hookworm disease in China: A study based on successive national surveillance
Huihui Zhu, Jilei Huang, Jinxin Zheng, Changhai Zhou, Tingjun Zhu, Mizhen Zhang, Luyuan Zhao, Xiaohong Wu, Jingbo Xue, Xiao-Nong Zhou, Shizhu Li, Menbao Qian
PLOS Neglected Tropical Diseases: published September 30, 2025 | https://doi.org/10.1371/journal.pntd.0013526
Effect of behavioral interventions on schistosomiasis-related knowledge, attitudes, and practices of schoolchildren in Pemba, Tanzania: A 4-year repeated cross-sectional study
Naomi Chi Ndum, Lydia Trippler, Ulfat Amour Mohammed, Mohammed Nassor Ali, Jan Hattendorf, Shaali Makame Ame, Fatma Kabole, Jürg Utzinger, Said Mohammed Ali, Stefanie Knopp
PLOS Neglected Tropical Diseases: published September 30, 2025 | https://doi.org/10.1371/journal.pntd.0013462
Local drivers of Rift Valley fever outbreaks in Mauritania: A one health approach combining ecological, vector, host and livestock movement data
Yahya Barry, Markus Metz, Lina Krisztian, Julia Haas, Victoria-Leandra Brunn, Abdellahi Diambar Beyit, Ahmed El Bara, Ahmed Bezeid El Mamy Beyat, Habiboulah Habiboulah, Markus Neteler, Catherine Cêtre-Sossah, Elena Arsevska
PLOS Neglected Tropical Diseases: published September 30, 2025 | https://doi.org/10.1371/journal.pntd.0013553