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Table of Contents

September 2025

Cover

Steep topography and environmental deficiencies, including open sewers and dense vegetation, in an informal settlement in Salvador, Brazil, where chikungunya virus exposure was studied. Travis et al. 2025

Image Credit: Dr. Max Eyre

Viewpoints

Mixing methods: How listening to researchers, healthcare workers, and community members can improve the design of studies testing medical innovations for Neglected Tropical Diseases

Astrid C. Erber, Anthony Ablordey, Adamu Addissie, Evans K. Ahortor, Doris Burtscher, Esther M. Mukooza, Richard Creswell, Ben Lambert, Piero L. Olliaro

PLOS Neglected Tropical Diseases: published September 30, 2025 | https://doi.org/10.1371/journal.pntd.0013547

Policy Platform

MoLEP—Co-creating a Mycobacterium leprae transmission interruption program for the Morogoro region, Tanzania

Tanja Barth-Jaeggi, Guy de Coulon, Issa Garimo, John Msaki, Liberate Mleoh, Riziki Kisonga, Sunil Modali, Shaishav Panchal, Shigela Marco Njebele, Shamez Sunderji, Kihulya Mageda, Peter Steinmann

PLOS Neglected Tropical Diseases: published September 19, 2025 | https://doi.org/10.1371/journal.pntd.0013507

Reviews

Orthohantavirus rodent hosts and genotypes in Southern South America: A narrative review

Natalia Ortiz, Juan Diego Pinotti, Verónica Andreo, Raúl Enrique González-Ittig, Cristina Noemí Gardenal

PLOS Neglected Tropical Diseases: published September 9, 2025 | https://doi.org/10.1371/journal.pntd.0013489

Guaroa virus, a forgotten Latin American orthobunyavirus: A narrative review

Carlos Ramiro Silva-Ramos, Patricia V. Aguilar

PLOS Neglected Tropical Diseases: published September 19, 2025 | https://doi.org/10.1371/journal.pntd.0013523

Research Articles

Concurrent chromoblastomycosis and eumycetoma: a unique case of dual neglected tropical fungal diseases in Asia

Wentao Liu, Shuxia Xie, Guoxing Zhu, Shitong Qin, Meirong Li, Songchao Yin, Wei Lai, Chun Lu, Qiaoping Chen, Peiying Feng

PLOS Neglected Tropical Diseases: published September 2, 2025 | https://doi.org/10.1371/journal.pntd.0013484

PANoptosis-mediated mechanisms underlying AST elevation in Talaromyces marneffei infection

Wudi Wei, Baili Zhan, Lixiang Chen, Gang Wang, Xiuli Bao, Xiaotao He, Meng Zhang, Xiaoting Xie, Weihong Huang, Zhiman Xie, Junjun Jiang, Hao Liang, Li Ye

PLOS Neglected Tropical Diseases: published September 2, 2025 | https://doi.org/10.1371/journal.pntd.0013443

Tracking the urban spread of Usutu virus in southern France: Detection across biological and environmental matrices

Rachel Beaubaton, Justine Revel, Laetitia Pigeyre, Karine Bollore, Alexandre Lepeule, Julien Mocq, Christophe de Franceschi, Julien Pradel, Yvon Perrin, David Gomis, Marie Ducousso, Laurie Virolle, Baptiste Chenet, Guillaume Castel, Anne Charmantier, Nathalie Charbonnel, Guillaume Lacour, Olivier Courot, Antoine Mignotte, Yannick Simonin

PLOS Neglected Tropical Diseases: published September 2, 2025 | https://doi.org/10.1371/journal.pntd.0013506

Future of snakebite risk in India: Consequence of climate change and the shifting habitats of the big four species in next five decades

Imon Abedin, Hey-Eun Kang, Hemanta Saikia, Won-Kyo Jung, Hyun-Woo Kim, Shantanu Kundu

PLOS Neglected Tropical Diseases: published September 2, 2025 | https://doi.org/10.1371/journal.pntd.0013464

From injury to outcome: A mixed-methods study of animal-related injuries in a rural district of Tanzania

Gimbo Hyuha, Notikela Nyamle, Manase Kilonzi, Paul Malaba Makoye, Castory Sananga Chuwa, Beatrice Aiko, Nathanael Sirili

PLOS Neglected Tropical Diseases: published September 2, 2025 | https://doi.org/10.1371/journal.pntd.0013494

Natural infection of filarioid nematodes in mosquitoes: An approach to neglected disease xenosurveillance and prevention in intercontinental human transit areas in Darién

Eddier Rivera, Anyi Tuñon, Mileyka Santos, Luisa Collado-Mariscal, Marlin González, Anayansi Valderrama

PLOS Neglected Tropical Diseases: published September 3, 2025 | https://doi.org/10.1371/journal.pntd.0013395

Stocking African catfish in Lake Victoria provides effective biocontrol of snail vectors of Schistosoma mansoni

Roland Proud, Fiona Allan, Andrew Whiston, Robert Kayanda, Safari Kinung’hi, Teckla Angelo, Yasinta D. Sylivester, Hillary D. J. Mrosso, Benedicto B. Kashindye, Mboni Elison, Martin J. Cox, Yang Yang, Andrew Chamberlin, Ian L. Boyd, David J. Civitello, Giulio A. De Leo, Andrew S. Brierley

PLOS Neglected Tropical Diseases: published September 3, 2025 | https://doi.org/10.1371/journal.pntd.0013490

The impact of temperature on canine Chagas disease transmission risk: A modeling study

Edem Fiatsonu, Sina Mokhtar, Martial L. Ndeffo-Mbah

PLOS Neglected Tropical Diseases: published September 3, 2025 | https://doi.org/10.1371/journal.pntd.0013498

The relationship between expelled eggs, morbidity and age in a Schistosoma mansoni endemic setting in Uganda: Implications for current elimination policies

Rivka M. Lim, Ruhi Lahoti, Jessica Clark, Moses Arinaitwe, Victor Anguajibi, Sergi Alonso, Andrina Nankasi, Fred Besigye, Alon Atuhaire, Amy B. Pedersen, Joanne P. Webster, Poppy H. L. Lamberton

PLOS Neglected Tropical Diseases: published September 3, 2025 | https://doi.org/10.1371/journal.pntd.0012750

Extreme weather events and dengue in Southeast Asia: A regionally-representative analysis of 291 locations from 1998 to 2021

Sophearen Ith, Xerxes Seposo, Vitou Phy, Kraichat Tantrakarnapa, Geminn Louis C. Apostol, Pandji Wibawa Dhewantara, Rozita Hod, Mohd Rohaizat Hassan, Hidayatulfathi Othman, Mazrura Sahani, Jue Tao Lim, Ha Hong Nhung, Nguyen Hai Tuan, Ngu Duy Nghia, Taichiro Takemura, Inthavong Nouhak, Paul L. C. Chua, Alex R. Cook, Felipe J. Colón-González, Masahiro Hashizume

PLOS Neglected Tropical Diseases: published September 4, 2025 | https://doi.org/10.1371/journal.pntd.0012649

Impact of Clonorchis sinensis infection on long-term survival after curative resection for hepatocellular carcinoma: A multicenter cohort study

Shuang Shen, Xin Qiu, Guodong Yang, Yi Peng, Haojie Yang, Jindu Li, Jiayin Qin, Huijie Tang, Huaiyue Liang, Wenyang Zhang, Hai Huang, Ze Su, Bangde Xiang

PLOS Neglected Tropical Diseases: published September 4, 2025 | https://doi.org/10.1371/journal.pntd.0013441

Kinome analysis of Madurella mycetomatis identified kinases in the cell wall integrity pathway as novel potential therapeutic drug targets in eumycetoma caused by Madurella mycetomatis

Mickey Konings, Nikolaos Strepis, Ri-Ichiroh Manabe, Akira Hasegawa, Somdatta Chaudhari, Saskia du Pré, Marij Schippers, Michihira Tagami, Jingyi Ma, Yasushi Okazaki, Matthew Todd, Bernhard Biersack, Vijay Masand, Annelies Verbon, Takeya Kasukawa, Imad Abugessaisa, Wendy W. J. van de Sande

PLOS Neglected Tropical Diseases: published September 4, 2025 | https://doi.org/10.1371/journal.pntd.0013482

BFD2 mediates inflammation, apoptosis, and pre-anxiety-like behaviors induced by acute Toxoplasma gondii infection

Xiaocheng Zhang, Tanzhen Xu, Jinjin Zhu, Hui Peng, Zixin Wei, Lijun Cui, Qingqiu Zuo, Hua Liu, Yuan Hu, Jianping Cao

PLOS Neglected Tropical Diseases: published September 4, 2025 | https://doi.org/10.1371/journal.pntd.0013428

Chromoblastomycosis and phaeohyphomycotic abscess-associated hospitalizations, United States, 2016–2021

Dallas J. Smith, Kaitlin Benedict, Shawn R. Lockhart, Sanjay G. Revankar

PLOS Neglected Tropical Diseases: published September 4, 2025 | https://doi.org/10.1371/journal.pntd.0013499

Surveillance of tick-borne viruses in the border regions of the Tumen River Basin: Co-circulation in ticks and livestock

Zhe Liu, Shengwei Ji, Qiaocheng Chang, Jinqi Wang, Eloiza May Galon, Ying Xu, Guolu Yin, Jixu Li, Xu Gao, Wannian Tian, Zhenzhen Han, Chenghui Li, Zhiqiang Xu, Rui Du, Shujiang Xue

PLOS Neglected Tropical Diseases: published September 4, 2025 | https://doi.org/10.1371/journal.pntd.0013500

Socio-psychological determinants of scabies contact notification among Dutch students: A qualitative study

Sunia B. Somra, Hélène A.C.M. Voeten, Inge Lewis - van Disseldorp, Fraukje E.F. Mevissen

PLOS Neglected Tropical Diseases: published September 4, 2025 | https://doi.org/10.1371/journal.pntd.0013471

Extracellular microbes are required for mosquito development even in the presence of Wolbachia

Javier Serrato-Salas, Yanouk Epelboin, Danai Bemplidaki, Ivan Roger, Mathilde Gendrin

PLOS Neglected Tropical Diseases: published September 5, 2025 | https://doi.org/10.1371/journal.pntd.0013481

Community deployment of metofluthrin emanators to control indoor Aedes aegypti: Efficacy results from a crossover trial in Yucatan, Mexico

Azael Che-Mendoza, Guillermo Guillermo-May, Oscar D. Kirstein, Aylin Chi-Ku, Norma Pavía-Ruz, Anuar Medina-Barreiro, Gabriela González-Olvera, Gregor Devine, Gonzalo Vazquez-Prokopec, Pablo Manrique-Saide

PLOS Neglected Tropical Diseases: published September 5, 2025 | https://doi.org/10.1371/journal.pntd.0012883

Taxonomic, molecular and ecological approach reveals high diversity of vector sand flies, varied blood source supply and a high detection rate of Leishmania DNA in Colombian Amazon region

Katerine Caviedes-Triana, Daniela Duque-Granda, Gloria Cadavid-Restrepo, Claudia X. Moreno-Herrera, Rafael Vivero-Gomez

PLOS Neglected Tropical Diseases: published September 5, 2025 | https://doi.org/10.1371/journal.pntd.0013445

Spatio-temporal analysis of the distribution and co-circulation of dengue, chikungunya, and Zika in Medellín, Colombia, from 2013 to 2021

Jorge E. Salazar Flórez, Berta N. Restrepo, Laís Picinini Freitas, Mabel Carabali, Gloria I. Jaramillo Ramírez, Cesar Garcia Balaguera, Brayan S. Avila Monsalve, Kate Zinszer

PLOS Neglected Tropical Diseases: published September 5, 2025 | https://doi.org/10.1371/journal.pntd.0013470

Topography and environmental deficiencies are associated with chikungunya virus exposure in urban informal settlements in Salvador, Brazil

Catherine Tamera Travis, Hernán D. Argibay, Maysa Pellizzaro, Daiana de Oliveira, Roberta Santana, Fabiana Almerinda G. Palma, Ricardo Lustosa, Juliet Oliveira Santana, Fábio Neves Souza, Yeimi Alexandra Alzate López, Mitermayer G. Reis, Albert I. Ko, Peter J. Diggle, Guilherme S. Ribeiro, Michael Begon, Federico Costa, Hussein Khalil, Max T. Eyre

PLOS Neglected Tropical Diseases: published September 5, 2025 | https://doi.org/10.1371/journal.pntd.0013477

Analysis of predictors of rabies-positive biting animals in Cambodia using spatio-temporal Bayesian regression modelling

Jerome N. Baron, Yik Sik Peng, Beatriz Martínez-López, Sowath Ly, Philippe Dussart, Véronique Chevalier

PLOS Neglected Tropical Diseases: published September 5, 2025 | https://doi.org/10.1371/journal.pntd.0013478

Risk factors and leprosy incidence among contacts in Bangladesh: A multilevel analysis

Unnati Rani Saha, Abu Sufian Chowdhury, Johan Chandra Roy, Khorshed Alam, Daan Nieboer, Renate Verbiest-Richardus, Annemieke Geluk, Jan Hendrik Richardus

PLOS Neglected Tropical Diseases: published September 5, 2025 | https://doi.org/10.1371/journal.pntd.0013465

Assessing the impact of tungiasis on children’s quality of life in Kenya

Lynne Elson, Berrick Otieno, Abneel K. Matharu, Naomi Riithi, Esther Jebor Chongwo, Francis Mutebi, Hermann Feldmeier, Jürgen Krücken, Ulrike Fillinger, Amina Abubakar

PLOS Neglected Tropical Diseases: published September 8, 2025 | https://doi.org/10.1371/journal.pntd.0012606

Impact of diabetes mellitus on adenolymphangitis episodes in patients with filarial lymphedema—Towards an integrated care approach

Nikita Kubal, Sowmiya Manavalan, Vijayakumar Balakrishnan, Nileshkumar Elangovan, Danapriyaa Dharmalingam, Vijesh Sreedhar Kuttiatt

PLOS Neglected Tropical Diseases: published September 8, 2025 | https://doi.org/10.1371/journal.pntd.0013486

Territorial and gender-linked risk factors for Buruli ulcer in Southern Benin: A case-control study using geographic and behavioral surveying

Harvey Johnson, Alexandra Boccarossa, Esai Anagonou, Télésphore Brou, Perin Catraye, Sébastien Fleuret, Estelle Marion, Matthieu Eveillard

PLOS Neglected Tropical Diseases: published September 8, 2025 | https://doi.org/10.1371/journal.pntd.0013509

Factors associated with health worker adoption of facial and environmental hygiene promotion in the ‘SAFE strategy’ for trachoma elimination in Western Province, Zambia

Martha Kasongo, Choolwe Jacobs, Adam Silumbwe, Patricia Maritim, Joseph Mumba Zulu, Hikabasa Halwindi

PLOS Neglected Tropical Diseases: published September 8, 2025 | https://doi.org/10.1371/journal.pntd.0013483

Geostatistical analysis to guide treatment decisions for soil-transmitted helminthiasis control in Uganda

Bryan O. Nyawanda, Kristin M. Sullivan, Benjamin Tinkitina, Prudence Beinamaryo, Betty Nabatte, Hilda Kyarisiima, Alfred Mubangizi, Paul M. Emerson, Jürg Utzinger, Penelope Vounatsou

PLOS Neglected Tropical Diseases: published September 8, 2025 | https://doi.org/10.1371/journal.pntd.0013467

Interstitial pneumonia via the oropharyngeal route of infection with Encephalitozoon cuniculi

Mariana Souza Santos, Rodrigo A. da Silva, Lucas Nunes de Souza, Nicolli R. Victorino, Rayane C.B. Pereira, José Guilherme Xavier, Ronalda da Silva Araújo, Elizabeth C. Pérez, Anuska M. Alvares-Saraiva, Maria Anete Lallo

PLOS Neglected Tropical Diseases: published September 8, 2025 | https://doi.org/10.1371/journal.pntd.0012130

People-centered strategies to mobilize people living with disabilities due to Neglected Tropical Diseases (PD-NTDs) to influence policy and programs: A mixed-methods study in Côte d’Ivoire

Julien Aké, Eunheh Koh, Tiembre Issiaka, Boko-Koiadia Adjoua N’Groma Nadège, Lorou Bi Maxime, Maneesh Phillip, Konan Anne Cécille, Rie Yotsu

PLOS Neglected Tropical Diseases: published September 8, 2025 | https://doi.org/10.1371/journal.pntd.0013485

Community-directed treatment with ivermectin in Maridi, South Sudan: Impact of an onchocerciasis awareness campaign and bi-annual treatment on therapeutic coverage

Joseph Nelson Siewe Fodjo, Moses Okwii, Stephen Raimon Jada, Amber Hadermann, Jacopo Rovarini, Luis-Jorge Amaral, Rogers Nditanchou, Yak Yak Bol, Makoy Y. Logora, Jane Y. Carter, Johan Willems, Robert Colebunders

PLOS Neglected Tropical Diseases: published September 8, 2025 | https://doi.org/10.1371/journal.pntd.0013493

Clinical, virological, and antibody profiles of overlapping dengue and chikungunya virus infections in children from southern Colombia

Daniela Polanía-Espinosa, Sebastián Castro-Trujillo, Carlos F. Narváez

PLOS Neglected Tropical Diseases: published September 8, 2025 | https://doi.org/10.1371/journal.pntd.0013260

The prevalence of trachoma, ocular Chlamydia trachomatis infection and anti-Pgp3 antibodies in Choiseul Province, Solomon Islands

Clare E. F. Dyer, Carleigh S. Cowling, Oliver Sokana, Lazarus Neko, Nemia Bainivalu, Freda Pitakaka, Anasaini Cama, Mitchel Starr, Emma M. Harding-Esch, Cristina Jimenez, Ana Bakhtiari, Sarah Boyd, Sara Webster, Anthony W. Solomon, John M. Kaldor, Susana Vaz Nery

PLOS Neglected Tropical Diseases: published September 8, 2025 | https://doi.org/10.1371/journal.pntd.0013381

Diversity of Salmonella enterica isolates from urban river and sewage water in Blantyre, Malawi

Jonathan Rigby, Catherine N. Wilson, Allan Zuza, Yohane Diness, Charity Mkwanda, Katalina Tonthola, Oscar Kanjerwa, Chifundo Salifu, Oliver Pearse, Chisomo Msefula, Blanca M. Perez-Sepulveda, Jay C.D. Hinton, Satheesh Nair, Nicola Elviss, Mathew A. Beale, Patrick Musicha, Nicholas A. Feasey

PLOS Neglected Tropical Diseases: published September 9, 2025 | https://doi.org/10.1371/journal.pntd.0012413

CLASV: Rapid Lassa virus lineage assignment with random forest

Richard Olumide Daodu, Ebenezer Awotoro, Jens-Uwe Ulrich, Denise Kühnert

PLOS Neglected Tropical Diseases: published September 9, 2025 | https://doi.org/10.1371/journal.pntd.0013512

Usability and quality evaluation of the World Health Organization SkinNTDs app among frontline health workers in Cameroon: A mixed methods study

Henri Claude Moungui, Paul Tonkoung Iyawa, Hugues Nana-Djeunga, Jose Antonio Ruiz-Postigo, Carme Carrion

PLOS Neglected Tropical Diseases: published September 10, 2025 | https://doi.org/10.1371/journal.pntd.0013461

Paratyphoid fever and the genomics of Salmonella enterica serovar Paratyphi A in Taiwan

Ying-Shu Liao, Yu-Ping Hong, Bo-Han Chen, You-Wun Wan, Ru-Hsiou Teng, Shiu-Yun Liang, Hsiao Lun Wei, Jui-Hsien Chang, Ming-Hao Yang, Chi-Sen Tsao, Chien-Shun Chiou

PLOS Neglected Tropical Diseases: published September 11, 2025 | https://doi.org/10.1371/journal.pntd.0013048

Clinical features and mortality risk factors in non-HIV elderly patients with cryptococcal meningitis: A retrospective cohort study from 2013 to 2022

Xiaofeng Xu, Xiaohong Su, Weipeng Li, Li Xu, Dongcheng Li, Kai Dai, Junyu Liu, Jia Liu, Fuhua Peng, Ying Jiang

PLOS Neglected Tropical Diseases: published September 11, 2025 | https://doi.org/10.1371/journal.pntd.0013521

Early events in dengue virus infection inducing cytokine storm: The dynamic interplay of pattern-recognition receptors, inflammasome activation, and biphasic NF-κB and STAT1-dependent inflammatory responses in human mononuclear phagocytes

Juan Felipe Valdés-López, Yordi Sebastián Tamayo-Molina, Geysson J. Fernandez, Lady Johana Hernández-Sarmiento, Paula A. Velilla, Silvio Urcuqui-Inchima

PLOS Neglected Tropical Diseases: published September 11, 2025 | https://doi.org/10.1371/journal.pntd.0013366

Glycosomal ABC transporter 3 (GAT3) deletion enhances the oxidative stress responses and reduces the infectivity of Trypanosoma cruzi

Davi Alvarenga Lima, Héllida Marina Costa-Silva, Karen Stephanie Sebe Albergaria, Juliana Martins Ribeiro, Daniela de Melo Resende, Bruno Alves Santarossa, Daniel Barbosa Liarte, Simone Guedes Calderano, Silvane Maria Fonseca Murta

PLOS Neglected Tropical Diseases: published September 11, 2025 | https://doi.org/10.1371/journal.pntd.0013479

Development and proof-of-concept evaluation for a low resource compatible Chikungunya virus diagnostic

Rickyle Balea, Alberto A. Amarilla, Jody Hobson-Peters, Joanne Macdonald, Andreas Suhrbier, Vasilli M. Kasimov, Daniel Watterson, Nina M. Pollak, David J. McMillan

PLOS Neglected Tropical Diseases: published September 12, 2025 | https://doi.org/10.1371/journal.pntd.0012352

Cryptosporidium parvum protease INS6 plays an important role in parasite proliferation and pathogenicity

Wei He, Zuwei Yang, Jing Wang, Fuxian Yang, Na Li, Rui Xu, Songrong Zeng, Lihua Xiao, Yaoyu Feng, Yaqiong Guo

PLOS Neglected Tropical Diseases: published September 12, 2025 | https://doi.org/10.1371/journal.pntd.0013532

Computational and experimental exploration of statin and statin-like compounds as potential treatment of schistosomiasis

Kehinde F. Paul-Odeniran, Paul O. Odeniran, Cécile Häberli, Jennifer Keiser, Charles A. Laughton

PLOS Neglected Tropical Diseases: published September 12, 2025 | https://doi.org/10.1371/journal.pntd.0013524

Whole genome sequencing of Yersinia pestis isolates from Central Asian natural plague foci revealed the role of adaptation to different hosts and environmental conditions in shaping specific genotypes

Aigul A. Abdirassilova, Duman T. Yessimseit, Altynai K. Kassenova, Beck Z. Abdeliyev, Zauresh B. Zhumadilova, Gulnara Zh. Tokmurziyeva, Galina G. Kovaleva, Ziyat Zh. Abdel, Tatiyana V. Meka-Mechenko, Saule K. Umarova, Elmira Zh. Begimbayeva, Sanzhar D. Agzam, Vladimir L. Motin, Oleg N. Reva, Altyn K. Rysbekova

PLOS Neglected Tropical Diseases: published September 12, 2025 | https://doi.org/10.1371/journal.pntd.0013533

Roles of tick-cofeeding hedgehogs in the natural transmission of spotted fever group Rickettsia

Haiming Yi, Weilin Huang, Changqiang Zhu, Yixin Ge, Xijing Yang, Sunjie Yang, Chuchu Ye, Junhu Wang, Qiong Chen, Yingqing Mao, Hongming Wang, Lele Ai, Wei Guo, Chao Chen, Weilong Tan, Yuexi Li, Yong Qi

PLOS Neglected Tropical Diseases: published September 15, 2025 | https://doi.org/10.1371/journal.pntd.0013224

Exploring the status of brucellosis in pregnant women presented with febrile illness at different healthcare facilities of Vehari and Lodhran zones of Pakistan

Syed Muhammad Tauseef Shafqat, Mian Muhammad Awais, Ulas Acaroz, Masood Akhtar, Abdul Sammad Ali Khan Shirwany, Imran Rasool, Naseer Ali Shah

PLOS Neglected Tropical Diseases: published September 15, 2025 | https://doi.org/10.1371/journal.pntd.0013525

Chikungunya virus in Thailand (2020–2023): Epidemiology, clinical features, and genomic insights

Sarawut Khongwichit, Watchaporn Chuchaona, Sumeth Korkong, Lakkhana Wongsrisang, Thanunrat Thongmee, Yong Poovorawan

PLOS Neglected Tropical Diseases: published September 15, 2025 | https://doi.org/10.1371/journal.pntd.0013548

Fixed-dose ivermectin for Mass Drug Administration: Is it time to leave the dose pole behind? Insights from an Individual Participant Data Meta-Analysis

Adriana Echazu, Daniela Bonanno, Pedro Emanuel Fleitas, Julie Jacobson, Gabriela Matamoros, Charles Mwandawiro, Wendemagegn Enbiale, Áuria de Jesus, Alan Brooks, Alejandro Javier Krolewiecki

PLOS Neglected Tropical Diseases: published September 15, 2025 | https://doi.org/10.1371/journal.pntd.0013059

Unexplained subcutaneous swelling: Keep echinococcosis in mind! Report of two primary extrahepatic subcutaneous echinococcosis cases and literature review

Louis Bohard, Eléonore Brumpt, Noémie Tissot, Marie Lacoste, Olivia Chapuis, Sophie Felix, Jenny Knapp, Carole Hartmann-Gouvenot, Yannick Jeffredo, Frederic Grenouillet, Damien Montange, Anne-Pauline Bellanger, Catherine Chirouze, Solange Bresson-Hadni

PLOS Neglected Tropical Diseases: published September 15, 2025 | https://doi.org/10.1371/journal.pntd.0013511

Disability and quality of life assessment using WHODAS-12 items 2.0 and EQ-5D-5L in a rural area endemic for loiasis in the Republic of Congo: A population-based cross-sectional study (the MorLo project)

Marlhand C. Hemilembolo, Jérémy T. Campillo, Valentin Dupasquier, Elodie Lebredonchel, Samuel Beneteau, Ludovic G. Rancé, Glorifié Madoulou Moulabou, Ange Clauvel Niama, Richard R. Bileckot, Sébastien D. S. Pion, Michel Boussinesq, François Missamou, Cédric B. Chesnais

PLOS Neglected Tropical Diseases: published September 15, 2025 | https://doi.org/10.1371/journal.pntd.0013491

Differentiating proven progressive disseminated histoplasmosis from other diagnoses in hospitalized persons with HIV and suspected progressive disseminated histoplasmosis: Findings from a clinical and demographic study in Mexico

Maria Dolores Niembro-Ortega, Areli Martinez-Gamboa, Antonio Olivas-Martinez, Brenda Crabtree-Ramirez, Janeth Santiago-Cruz, Andrea Rangel-Cordero, Pedro Torres-Gonzalez, Armando Gamboa-Dominguez, Victor Hugo Lozano-Fernandez, Victor Hugo Ahumada-Topete, Pedro Martinez-Ayala, Marisol Manriquez-Reyes, Juan Pablo Ramirez-Hinojosa, Patricia Rodriguez-Zulueta, Jesus Ruiz-Quiñones, Christian Hernandez-Leon, Norma Erendira Rivera-Martinez, Alberto Chaparro-Sanchez, Jaime Andrade-Villanueva, Luz Alicia Gonzalez-Hernandez, Sofia Cruz-Martinez, Oscar Flores-Barrientos, Jesus Enrique Gaytan-Martinez, Axel Cervantes Sanchez, Nancy Guadalupe Velazquez-Zavala, Maria del Rocio Reyes-Montes, Esperanza Duarte Escalante, Maria Guadalupe Frias De Leon, Jose Antonio Ramirez, Maria Lucia Taylor, Jose Sifuentes-Osornio, Alfredo Ponce de Leon

PLOS Neglected Tropical Diseases: published September 17, 2025 | https://doi.org/10.1371/journal.pntd.0013527

Exploration of tongue dorsum sampling to support clinical diagnosis of leprosy patients in the Comoros: A cross-sectional study

Lena Krausser, Maren Van Nieuwenhove, Nissad Attoumani, Silahi H. Grillone, Magalie Van Dyck-Lippens, Leen Rigouts, Abdallah Baco, Wirdane Abdou, Aboubacar Mzembaba, Epco Hasker, Younoussa Assoumani, Bouke C. de Jong, Sofie M. Braet

PLOS Neglected Tropical Diseases: published September 17, 2025 | https://doi.org/10.1371/journal.pntd.0013541

Assessing the need to implement mass drug administration against Wuchereria bancrofti infection using both human serology and xenomonitoring in the urban conurbation of Monrovia, Liberia

Benjamin G. Koudou, Rogers Nditanchou, Firmain N. Yokoly, Abakar Gankpala, Karsor K. Kollie, David Molyneux, Philip Downs, Ruth Dixon

PLOS Neglected Tropical Diseases: published September 18, 2025 | https://doi.org/10.1371/journal.pntd.0013446

Scrub typhus in Nan province (Thailand): Seventeen years of data to understand the impact of land cover change

Nolwenn Blache, Karine Chalvet-Monfray, Rawadee Kumlert, Soawapak Hinjoy, Serge Morand

PLOS Neglected Tropical Diseases: published September 18, 2025 | https://doi.org/10.1371/journal.pntd.0013552

Interleukin-10 limits immune-mediated pathology in chronic subclinical plasmodial infection

Leandro de Souza Silva, Brian G. Monks, Catherine S. Forconi, Juliet N. Crabtree, Nelsy De Paula Tamburro, Evelyn A. Kurt-Jones, Ricardo T. Gazzinelli, Katherine A. Fitzgerald, Douglas T. Golenbock

PLOS Neglected Tropical Diseases: published September 19, 2025 | https://doi.org/10.1371/journal.pntd.0013554

Detection of potential transmission foci of lymphatic filariasis using molecular xenomonitoring in Huahine, French Polynesia

Reva Lannuzel, Tanagra Lambert, Farah Deen, Hmeniko Tourancheau, Jérôme Marie, Michel A. Cheong Sang, Manfred Mervin, Benoit Stoll, Hervé C. Bossin, Françoise Mathieu-Daudé

PLOS Neglected Tropical Diseases: published September 19, 2025 | https://doi.org/10.1371/journal.pntd.0013492

Topical AuNPs-Cys-Sm29 gel modulates the course of lesion development in experimental cutaneous leishmaniasis

Sayonara de M. Viana, Luciana Cardoso, Pedro B. Borba, Lucas P. Carvalho, Juvana Moreira, Fabio Mambelli, Sergio C. Oliveira, Edgar M. Carvalho, Camila I. de Oliveira

PLOS Neglected Tropical Diseases: published September 22, 2025 | https://doi.org/10.1371/journal.pntd.0013510

Etiological spectrum and diagnostic features of lymphadenopathy in People Living with HIV in French Guiana: A 17-years multicenter retrospective case series

Morgane Bourne-Watrin, Ugo Françoise, Sophie Alexandra Baron, Antoine A. Adenis, Dufens Pierre Louis, Loïc Epelboin, Mathieu Nacher, Félix Djossou, Kinan Drak Alsibai, Pierre Couppié

PLOS Neglected Tropical Diseases: published September 22, 2025 | https://doi.org/10.1371/journal.pntd.0013558

Endemicity, disability and neglect: Leprosy in Colombia 2007–2020

Carlos Arango-Úsuga, Jesús Ochoa, Doracelly Hincapié-Palacio, Alba León

PLOS Neglected Tropical Diseases: published September 22, 2025 | https://doi.org/10.1371/journal.pntd.0013514

Antibody responses to Japanese encephalitis virus and dengue virus serotype 2 in children from an orthoflavivirus endemic region after IMOJEV vaccination

Fatima Ericka S. Vista, Leslie Michelle M. Dalmacio, Pauline R. Solis, Cecilia Nelia C. Maramba-Lazarte, Diane M. Lang, Alan L. Rothman, Sheriah Laine M. de Paz-Silava

PLOS Neglected Tropical Diseases: published September 22, 2025 | https://doi.org/10.1371/journal.pntd.0013550

Population pharmacokinetic-pharmacodynamic analysis of benznidazole monotherapy and combination therapy with fosravuconazole in chronic Chagas disease (BENDITA)

Frauke Assmus, Cintia Cruz, James A. Watson, Nicholas J. White, Ayorinde Adehin, Richard M. Hoglund, Bethania Blum de Oliveira, Fabiana Barreira, Ivan Scandale, Joel Tarning

PLOS Neglected Tropical Diseases: published September 22, 2025 | https://doi.org/10.1371/journal.pntd.0013522

Anti-inflammatory cytokine profile and Jarisch-Herxheimer reaction in Leptospirosis patients: A prospective case-series study in New Caledonia

Julie Cagliero, Anne Loarec, Julien Lebon, François Baur, Patrick Lefevre, Emilie Follenfant, Cyrille Goarant, Damaris Ukeiwe, Julien Colot, Sylvie Tardieu, Catherine Werts, Cécile Cazorla

PLOS Neglected Tropical Diseases: published September 23, 2025 | https://doi.org/10.1371/journal.pntd.0013189

Optimizing the implementation of case-area targeted interventions during cholera outbreaks with context-specific delivery mechanisms

Jessica Dunoyer, Ruwan Ratnayake, Sandy Moore, Gregory Bulit, Samuel Beaulieu, Christophe Valingot, Pierre-Yves Oger, Bertrand Sudre, Daniele Lantagne, Nicola Desmond

PLOS Neglected Tropical Diseases: published September 23, 2025 | https://doi.org/10.1371/journal.pntd.0013534

Identifying hotspots of S. haematobium infection following praziquantel treatment during multiple annual mass drug administration campaigns in Zimbabwe

Takafira Mduluza, Grace Zdesenko, Paradzayi Tagwireyi, Caitlin M. Jones, Francisca Mutapi

PLOS Neglected Tropical Diseases: published September 24, 2025 | https://doi.org/10.1371/journal.pntd.0013546

Proteomic-based identification of novel EV-derived protein antibodies biomarkers for melioidosis diagnosis

Nini Luo, Jun Tan, Xuemiao Li, Yanshuang Wang, Ting Zhang, Chen Chen, Lin Liu, Xinyi Song, Hua Pei, Bo Wang, Qi Li, Shen Tian, Nan Zhang, Wei Cheng, Qianfeng Xia

PLOS Neglected Tropical Diseases: published September 24, 2025 | https://doi.org/10.1371/journal.pntd.0013543

A multifaceted molecular approach to surveillance of leishmaniasis: Identification of sand fly species, Leishmania parasites, and blood meal sources using high-resolution melting analysis

Liora Studentsky, Fouad Akad, Debora Diaz, Irina Ben Avi, Shirly Lea Elbaz, Tamar Grossman, Maya Davidovich-Cohen, Oscar David Kirstein, Laor Orshan, Gad Baneth

PLOS Neglected Tropical Diseases: published September 24, 2025 | https://doi.org/10.1371/journal.pntd.0013412

Comparing diagnostic methods for historical arbovirus outbreaks: Insights from 19th century "dengue" epidemics

Timothee Bonifay, Mathieu Nacher, Clémence Bonnefoy, Benjamin Rossi, Edouard Hallet, Philippe Abboud, Guillaume Bellaud, Nathalie Dournon, Aurélia Henn, Adrien Lemaignen, Liem Binh Luong Nguyen, Diane Sanderink, Gaelle Walter, Alexandre Bleibtreu, Loïc Epelboin

PLOS Neglected Tropical Diseases: published September 26, 2025 | https://doi.org/10.1371/journal.pntd.0013551

Drivers of rabies virus spillover risk from vampire bats to livestock in Colombia

Paige Van de Vuurst, Cassidy Rist, Tatiana Medina-Rodriguez, Andres Felipe Osejo-Varona, Diego Soler-Tovar, Luis E. Escobar

PLOS Neglected Tropical Diseases: published September 26, 2025 | https://doi.org/10.1371/journal.pntd.0013508

Landscape-scale analysis of raccoon rabies surveillance reveals different drivers of disease dynamics across latitude

Matthew Michalska-Smith, Meggan E. Craft, Amy J. Davis, Amy T. Gilbert, Richard B. Chipman, Jordona Kirby, Kathleen M. Nelson, Xiaoyue Ma, Ryan Wallace, Grace Miller, Kim M. Pepin

PLOS Neglected Tropical Diseases: published September 26, 2025 | https://doi.org/10.1371/journal.pntd.0013581

Hematological diseases-related mucormycosis: A retrospective single center study

Yu Cui, Rui Zhao, Ruihua Mi, Lin Chen, Lin Wang, Dongbei Li, Cheng Cheng, Mengjuan Li, Xudong Wei

PLOS Neglected Tropical Diseases: published September 26, 2025 | https://doi.org/10.1371/journal.pntd.0013531

Leptospirosis in Campinas, Brazil: The interplay between drainage, impermeable areas, and social vulnerability

Thiago Salomão de Azevedo, Shahista Nisa, Stuart Littlejohn, Renata L. Muylaert

PLOS Neglected Tropical Diseases: published September 29, 2025 | https://doi.org/10.1371/journal.pntd.0013560

A district-level ensemble model to enhance dengue prediction and control for the Mekong Delta Region of Vietnam

Wala Draidi Areed, Thi Thanh Thao Nguyen, Kien Quoc Do, Thinh Nguyen, Vinh Bui, Elisabeth Nelson, Joshua L. Warren, Quang-Van Doan, Nam Vu Sinh, Nicholas John Osborne, Russell Richards, Nu Quy Linh Tran, Hong Le, Tuan Pham, Trinh Manh Hung, Son Nghiem, Hai Phung, Cordia Chu, Robert Dubrow, Daniel M. Weinberger, Dung Phung

PLOS Neglected Tropical Diseases: published September 29, 2025 | https://doi.org/10.1371/journal.pntd.0013571

Passive surveillance of human African trypanosomiasis in the Democratic Republic of the Congo: clinical presentation and prospective evaluation of rapid diagnostic and reference laboratory test accuracy

Jacquies Makabuza, Ipos Ngay Lukusa, Crispin Lumbala, Erick Mwamba Miaka, Pathou Nganzobo, Alain Fukinsia, Jean Kwete, Nicolas Bebronne, Philippe Büscher, Dieudonné Mumba Ngoyi, Veerle Lejon

PLOS Neglected Tropical Diseases: published September 29, 2025 | https://doi.org/10.1371/journal.pntd.0013045

Molecular epidemiology of panton valentine leukocidin-producing Staphylococcus aureus infections, Djibouti, 2018–2023

Maxime Danjean, Virginie Courbin, Aurore Ho, Aurore Bousquet, Christophe Rodriguez, Hervé Jacquier, Paul-Louis Woerther

PLOS Neglected Tropical Diseases: published September 30, 2025 | https://doi.org/10.1371/journal.pntd.0013544

Knowledge, attitudes, and practices on anthrax in selected game management areas in Zambia

Exillia Kabbudula, Laila Gondwe, Chitwambi Makungu, Mtui-Malamsha N. Jesse, Kezzy Besa, Suwilanji S. Sichone, Noanga Mebelo, Mwila Kayula, Geoffrey Mainda, Fredrick M. Kivaria, Charles Bebay, Baba Soumare, Suze P. Filippini, Chisoni Mumba

PLOS Neglected Tropical Diseases: published September 30, 2025 | https://doi.org/10.1371/journal.pntd.0013592

Circulating Angiopoietin-like proteins in Strongyloides Stercoralis infection and reversal following treatment

Anuradha Rajamanickam, Saravanan Munisankar, Subash Babu

PLOS Neglected Tropical Diseases: published September 30, 2025 | https://doi.org/10.1371/journal.pntd.0013559

Spatial distribution patterns and risk factors of hookworm disease in China: A study based on successive national surveillance

Huihui Zhu, Jilei Huang, Jinxin Zheng, Changhai Zhou, Tingjun Zhu, Mizhen Zhang, Luyuan Zhao, Xiaohong Wu, Jingbo Xue, Xiao-Nong Zhou, Shizhu Li, Menbao Qian

PLOS Neglected Tropical Diseases: published September 30, 2025 | https://doi.org/10.1371/journal.pntd.0013526

Effect of behavioral interventions on schistosomiasis-related knowledge, attitudes, and practices of schoolchildren in Pemba, Tanzania: A 4-year repeated cross-sectional study

Naomi Chi Ndum, Lydia Trippler, Ulfat Amour Mohammed, Mohammed Nassor Ali, Jan Hattendorf, Shaali Makame Ame, Fatma Kabole, Jürg Utzinger, Said Mohammed Ali, Stefanie Knopp

PLOS Neglected Tropical Diseases: published September 30, 2025 | https://doi.org/10.1371/journal.pntd.0013462

Local drivers of Rift Valley fever outbreaks in Mauritania: A one health approach combining ecological, vector, host and livestock movement data

Yahya Barry, Markus Metz, Lina Krisztian, Julia Haas, Victoria-Leandra Brunn, Abdellahi Diambar Beyit, Ahmed El Bara, Ahmed Bezeid El Mamy Beyat, Habiboulah Habiboulah, Markus Neteler, Catherine Cêtre-Sossah, Elena Arsevska

PLOS Neglected Tropical Diseases: published September 30, 2025 | https://doi.org/10.1371/journal.pntd.0013553

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