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Table of Contents

September 2023

Cover

During an inventory in Pha Tong cave, Thailand, two collected species could not be related to known sand fly species. The first new species, Phlebotomus shadenae n. sp. is a sand fly of the subgenus Anaphlebotomus. It is morphologically close to Ph. stantoni, a species widely distributed throughout Southeast Asia. However, it differs by the length of the genital filaments or ducts of the spermathecae as well as the high divergence of cytochrome b sequences. The second new species, Sergentomyia maiae n. sp., differs from a species in the same group, Se. barraudi, by an original cibarial double row of vertical teeth as well as by molecular data. Renaux Torres and Pellot et al, 2023

Image Credit: Jérôme Depaquit

Viewpoints

How to find a forgotten disease like yaws: Lessons from the Philippine experience

Belen Lardizabal Dofitas

PLOS Neglected Tropical Diseases: published September 14, 2023 | https://doi.org/10.1371/journal.pntd.0011515

The road towards protection of all against tetanus

Md. Abdullah Saeed Khan, Mohammad Jahid Hasan, Mohammad Delwer Hossain Hawlader

PLOS Neglected Tropical Diseases: published September 21, 2023 | https://doi.org/10.1371/journal.pntd.0011611

Reviews

Shigella and childhood stunting: Evidence, gaps, and future research directions

Karoun H. Bagamian, John D. Anderson IV, Gabriela Blohm, Suzanne Scheele

PLOS Neglected Tropical Diseases: published September 12, 2023 | https://doi.org/10.1371/journal.pntd.0011475

Better efficacy of triple antibiotics therapy for human brucellosis: A systematic review and meta-analysis

Shanjun Huang, Hao Wang, Fande Li, Lanping Du, Wenqi Fan, Meifang Zhao, Hua Zhen, Yuke Yan, Menghan Lu, Xin Han, Zhuo Li, Mujinyan Li, Shuqi An, Xinyao Zhang, Qing Zhen, Tiejun Shui

PLOS Neglected Tropical Diseases: published September 14, 2023 | https://doi.org/10.1371/journal.pntd.0011590

Research Articles

Comparison of collection methods for Phlebotomus argentipes sand flies to use in a molecular xenomonitoring system for the surveillance of visceral leishmaniasis

Shannon McIntyre-Nolan, Vijay Kumar, Miguella Mark-Carew, Kundan Kumar, Emily S. Nightingale, Giorgia Dalla Libera Marchiori, Matthew E. Rogers, Mojca Kristan, Susana Campino, Graham F. Medley, Pradeep Das, Mary M. Cameron

PLOS Neglected Tropical Diseases: published September 1, 2023 | https://doi.org/10.1371/journal.pntd.0011200

Fungal infections in Sudan: An underestimated health problem

Sarah A. Ahmed, Mawahib Ismail, Mohamed Albirair, Abdelsalam Mohamed Ahmed Nail, David W. Denning

PLOS Neglected Tropical Diseases: published September 1, 2023 | https://doi.org/10.1371/journal.pntd.0011464

A structural classification of the variant surface glycoproteins of the African trypanosome

Sara Đaković, Johan P. Zeelen, Anastasia Gkeka, Monica Chandra, Monique van Straaten, Konstantina Foti, Janet Zhong, Evi P. Vlachou, Francisco Aresta-Branco, Joseph P. Verdi, F. Nina Papavasiliou, C. Erec Stebbins

PLOS Neglected Tropical Diseases: published September 1, 2023 | https://doi.org/10.1371/journal.pntd.0011621

Direct mosquito feedings on dengue-2 virus-infected people reveal dynamics of human infectiousness

Louis Lambrechts, Robert C. Reiner Jr, M. Veronica Briesemeister, Patricia Barrera, Kanya C. Long, William H. Elson, Alfonso Vizcarra, Helvio Astete, Isabel Bazan, Crystyan Siles, Stalin Vilcarromero, Mariana Leguia, Anna B. Kawiecki, T. Alex Perkins, Alun L. Lloyd, Lance A. Waller, Uriel Kitron, Sarah A. Jenkins, Robert D. Hontz, Wesley R. Campbell, Lauren B. Carrington, Cameron P. Simmons, J. Sonia Ampuero, Gisella Vasquez, John P. Elder, Valerie A. Paz-Soldan, Gonzalo M. Vazquez-Prokopec, Alan L. Rothman, Christopher M. Barker, Thomas W. Scott, Amy C. Morrison

PLOS Neglected Tropical Diseases: published September 1, 2023 | https://doi.org/10.1371/journal.pntd.0011593

Primary cerebral cystic echinococcosis in a child from Roman countryside: Source attribution and scoping review of cases from the literature

Adriano Casulli, Stefania Pane, Franco Randi, Paola Scaramozzino, Andrea Carvelli, Carlo Efisio Marras, Andrea Carai, Azzurra Santoro, Federica Santolamazza, Francesca Tamarozzi, Lorenza Putignani

PLOS Neglected Tropical Diseases: published September 5, 2023 | https://doi.org/10.1371/journal.pntd.0011612

Jamestown Canyon virus is transmissible by Aedes aegypti and is only moderately blocked by Wolbachia co-infection

Meng-Jia Lau, Heverton L. C. Dutra, Matthew J. Jones, Brianna P. McNulty, Anastacia M. Diaz, Fhallon Ware-Gilmore, Elizabeth A. McGraw

PLOS Neglected Tropical Diseases: published September 5, 2023 | https://doi.org/10.1371/journal.pntd.0011616

A drug repurposing screen for whipworms informed by comparative genomics

Avril Coghlan, Frederick A. Partridge, María Adelaida Duque-Correa, Gabriel Rinaldi, Simon Clare, Lisa Seymour, Cordelia Brandt, Tapoka T. Mkandawire, Catherine McCarthy, Nancy Holroyd, Marina Nick, Anwen E. Brown, Sirapat Tonitiwong, David B. Sattelle, Matthew Berriman

PLOS Neglected Tropical Diseases: published September 5, 2023 | https://doi.org/10.1371/journal.pntd.0011205

Assessment of knowledge, attitude, and practice of dog owners to rabies disease in Kahama town council, Shinyanga region, Tanzania

Shabani Iddi, Farida Mlenga, Kayo Hamasaki, Stanley Mwita, Eveline Konje

PLOS Neglected Tropical Diseases: published September 6, 2023 | https://doi.org/10.1371/journal.pntd.0011580

Weekly primaquine for radical cure of patients with Plasmodium vivax malaria and glucose-6-phosphate dehydrogenase deficiency

Walter R. J. Taylor, Niamh Meagher, Benedikt Ley, Kamala Thriemer, Germana Bancone, Ari Satyagraha, Ashenafi Assefa, Krisin Chand, Nguyen Hoang Chau, Mehul Dhorda, Tamiru S. Degaga, Lenny L. Ekawati, Asrat Hailu, Mohammad Anwar Hasanzai, Mohammad Nader Naddim, Ayodhia Pitaloka Pasaribu, Awab Ghulam Rahim, Inge Sutanto, Ngo Viet Thanh, Nguyen Thi Tuyet-Trinh, Naomi Waithira, Adugna Woyessa, Arjen Dondorp, Lorenz von Seidlein, Julie A. Simpson, Nicholas J. White, J. Kevin Baird, Nicholas P. Day, Ric N. Price

PLOS Neglected Tropical Diseases: published September 6, 2023 | https://doi.org/10.1371/journal.pntd.0011522

How correlations between treatment access and surveillance inclusion impact neglected tropical disease monitoring and evaluation—A simulated study

Jessica Clark, Emma L. Davis, Joaquin M. Prada, Katherine Gass, Alison Krentel, T. Déirdre Hollingsworth

PLOS Neglected Tropical Diseases: published September 6, 2023 | https://doi.org/10.1371/journal.pntd.0011582

A cross-sectional investigation of Leptospira at the wildlife-livestock interface in New Zealand

Marie Moinet, Hedwich Oosterhof, Shahista Nisa, Neville Haack, David A. Wilkinson, Danielle Aberdein, James C. Russell, Emilie Vallée, Julie Collins-Emerson, Cord Heuer, Jackie Benschop

PLOS Neglected Tropical Diseases: published September 6, 2023 | https://doi.org/10.1371/journal.pntd.0011624

Exploring the antimicrobial peptidome of nematodes through phylum-spanning in silico analyses highlights novel opportunities for pathogen control

Allister Irvine, Sharon A. Huws, Louise E. Atkinson, Angela Mousley

PLOS Neglected Tropical Diseases: published September 6, 2023 | https://doi.org/10.1371/journal.pntd.0011618

Socioenvironmental determinants as indicators of plague risk in the central highlands of Madagascar: Experience of Ambositra and Tsiroanomandidy districts

Sitraka Rakotosamimanana, François Taglioni, Masiarivony Ravaoarimanga, Minoarisoa Esther Rajerison, Fanjasoa Rakotomanana

PLOS Neglected Tropical Diseases: published September 6, 2023 | https://doi.org/10.1371/journal.pntd.0011538

Convergent trends and spatiotemporal patterns of Aedes-borne arboviruses in Mexico and Central America

Bernardo Gutierrez, Darlan da Silva Candido, Sumali Bajaj, Abril Paulina Rodriguez Maldonado, Fabiola Garces Ayala, María de la Luz Torre Rodriguez, Adnan Araiza Rodriguez, Claudia Wong Arámbula, Ernesto Ramírez González, Irma López Martínez, José Alberto Díaz-Quiñónez, Mauricio Vázquez Pichardo, Sarah C. Hill, Julien Thézé, Nuno R. Faria, Oliver G. Pybus, Lorena Preciado-Llanes, Arturo Reyes-Sandoval, Moritz U. G. Kraemer, Marina Escalera-Zamudio

PLOS Neglected Tropical Diseases: published September 6, 2023 | https://doi.org/10.1371/journal.pntd.0011169

Coverage evaluation of mass drug administration with triple drug regimen in an evaluation unit in Nagpur district of Maharashtra, India

Raja Jeyapal Dinesh, Adinarayanan Srividya, Swaminathan Subramanian, Kaliannagounder Krishnamoorthy, Shanmugavelu Sabesan, Monika Charmode Raghorte, Ashwani Kumar, Purushothaman Jambulingam

PLOS Neglected Tropical Diseases: published September 7, 2023 | https://doi.org/10.1371/journal.pntd.0011588

Adipokine levels and their association with clinical disease severity in patients with dengue

Heshan Kuruppu, W. P Rivindu H. Wickramanayake, Chandima Jeewandara, Deneshan Peranantharajah, H. S. Colambage, Lahiru Perera, Laksiri Gomes, Ananda Wijewickrama, Graham S. Ogg, Gathsaurie Neelika Malavige

PLOS Neglected Tropical Diseases: published September 7, 2023 | https://doi.org/10.1371/journal.pntd.0011613

Case series of 12 Bartonella quintana endocarditis from the Southwest Indian Ocean

Ludivine Sarsiat, Thomas Garrigos, Linda Houhamdi, Olivier Dauwalder, Barbara Kuli, Eric Braunberger, Olivier Belmonte, Pierre-Edouard Fournier, Guillaume Miltgen

PLOS Neglected Tropical Diseases: published September 7, 2023 | https://doi.org/10.1371/journal.pntd.0011606

Temporal changes in pathology and viral RNA distribution in guinea pigs following separate infection with two New World Arenaviruses

Curtis Cline, Xiankun Zeng, Todd M. Bell, Carl Shaia, Paul Facemire, Janice Williams, Neil Davis, April Babka, Edwin Picado, Colin Fitzpatrick, Joseph W. Golden

PLOS Neglected Tropical Diseases: published September 8, 2023 | https://doi.org/10.1371/journal.pntd.0011620

Evaluation of models for multi-step forecasting of hand, foot and mouth disease using multi-input multi-output: A case study of Chengdu, China

Xiaoran Geng, Yue Ma, Wennian Cai, Yuanyi Zha, Tao Zhang, Huadong Zhang, Changhong Yang, Fei Yin, Tiejun Shui

PLOS Neglected Tropical Diseases: published September 8, 2023 | https://doi.org/10.1371/journal.pntd.0011587

Molecular characterization of a novel serine proteinase from Trichinella spiralis and its participation in larval invasion of gut epithelium

Yan Yan Song, Xin Zhuo Zhang, Bo Ning Wang, Min Min Weng, Zhao Yu Zhang, Xin Guo, Xi Zhang, Zhong Quan Wang, Jing Cui

PLOS Neglected Tropical Diseases: published September 11, 2023 | https://doi.org/10.1371/journal.pntd.0011629

Prevalence of soil-transmitted helminths and associated risk factors among primary school children in Kandahar, Afghanistan: A cross-sectional analytical study

Bilal Ahmad Rahimi, Najeebullah Rafiqi, Zarghoon Tareen, Khalil Ahmad Kakar, Mohammad Hashim Wafa, Muhammad Haroon Stanikzai, Mohammad Asim Beg, Abdul Khaliq Dost, Walter R. Taylor

PLOS Neglected Tropical Diseases: published September 11, 2023 | https://doi.org/10.1371/journal.pntd.0011614

The genomes of the yaws bacterium, Treponema pallidum subsp. pertenue, of nonhuman primate and human origin are not genomically distinct

Klára Janečková, Christian Roos, Pavla Fedrová, Nikola Tom, Darina Čejková, Simone Lueert, Julius D. Keyyu, Idrissa S. Chuma, Sascha Knauf, David Šmajs

PLOS Neglected Tropical Diseases: published September 13, 2023 | https://doi.org/10.1371/journal.pntd.0011602

Preliminary characterization of Plasmodium vivax sporozoite antigens as pre-erythrocytic vaccine candidates

Justin Nicholas, Sai Lata De, Pongsakorn Thawornpan, Awtum M. Brashear, Surendra Kumar Kolli, Pradeep Annamalai Subramani, Samantha J. Barnes, Liwang Cui, Patchanee Chootong, Francis Babila Ntumngia, John H. Adams

PLOS Neglected Tropical Diseases: published September 13, 2023 | https://doi.org/10.1371/journal.pntd.0011598

Reporting delays of chikungunya cases during the 2017 outbreak in Lazio region, Italy

Mattia Manica, Giovanni Marini, Angelo Solimini, Giorgio Guzzetta, Piero Poletti, Paola Scognamiglio, Chiara Virgillito, Alessandra della Torre, Stefano Merler, Roberto Rosà, Francesco Vairo, Beniamino Caputo

PLOS Neglected Tropical Diseases: published September 14, 2023 | https://doi.org/10.1371/journal.pntd.0011610

Paracoccidioidomycosis and pregnancy: A 40-year single-center cohort study in the endemic area of Rio de Janeiro, Brazil

Lorena Macedo Pestana Benko, Mariana Evangelista de Souza Vieira da Silva, Eduardo Mastrangelo Marinho Falcão, Dayvison Francis Saraiva Freitas, Guilherme Amaral Calvet, Marcos de Abreu Almeida, Rodrigo Almeida-Paes, Rosely Maria Zancopé-Oliveira, Antonio Carlos Francesconi do Valle, Priscila Marques de Macedo

PLOS Neglected Tropical Diseases: published September 14, 2023 | https://doi.org/10.1371/journal.pntd.0011645

Genome-informed investigation of the molecular evolution and genetic reassortment of severe fever with thrombocytopenia syndrome virus

Kyuyoung Lee, Jong Hyeon Seok, Hyunbeen Kim, Sejik Park, Sohyun Lee, Joon-Yong Bae, Kyeongseok Jeon, Jun-Gu Kang, Jeong Rae Yoo, Sang Taek Heo, Nam-Hyuk Cho, Keun Hwa Lee, Kisoon Kim, Man-Seong Park, Jin Il Kim

PLOS Neglected Tropical Diseases: published September 15, 2023 | https://doi.org/10.1371/journal.pntd.0011630

Strasseriolides display in vitro and in vivo activity against trypanosomal parasites and cause morphological and size defects in Trypanosoma cruzi

Cristina Bosch-Navarrete, Guiomar Pérez-Moreno, Frederick Annang, Rosario Diaz-Gonzalez, Raquel García-Hernández, Hedy Rocha, Francisco Gamarro, Carlos Cordón-Obras, Miguel Navarro, Ana Rodriguez, Olga Genilloud, Fernando Reyes, Francisca Vicente, Luis M. Ruiz-Pérez, Dolores González-Pacanowska

PLOS Neglected Tropical Diseases: published September 15, 2023 | https://doi.org/10.1371/journal.pntd.0011592

Cutaneous disseminated sporotrichosis associated with diabetes: A case report and literature review

Xiujiao Xia, Huilin Zhi, Zehu Liu

PLOS Neglected Tropical Diseases: published September 18, 2023 | https://doi.org/10.1371/journal.pntd.0011647

Specific and sensitive loop-mediated isothermal amplification (LAMP) method for Madurella strains, eumycetoma filamentous fungi causative agent

Isato Yoshioka, Yugo Mori, Ahmed Hassan Fahal, Emmanuel Edwar Siddig, Satoshi Kaneko, Takashi Yaguchi

PLOS Neglected Tropical Diseases: published September 18, 2023 | https://doi.org/10.1371/journal.pntd.0011644

Safety and tolerability of moxidectin and ivermectin combination treatments for lymphatic filariasis in Côte d’Ivoire: A randomized controlled superiority study

Catherine M. Bjerum, Benjamin G. Koudou, Allassane F. Ouattara, Daphne Lew, Charles W. Goss, Pascal T. Gabo, Christopher L. King, Peter U. Fischer, Gary J. Weil, Philip J. Budge

PLOS Neglected Tropical Diseases: published September 18, 2023 | https://doi.org/10.1371/journal.pntd.0011633

Label-free quantitative proteomic analyses of mouse astrocytes provides insight into the host response mechanism at different developmental stages of Toxoplasma gondii

Huanhuan Xie, Hang Sun, Hongjie Dong, Lisha Dai, Haozhi Xu, Lixin Zhang, Qi Wang, Junmei Zhang, Guihua Zhao, Chao Xu, Kun Yin

PLOS Neglected Tropical Diseases: published September 18, 2023 | https://doi.org/10.1371/journal.pntd.0011102

Quantitative proteomics analysis of permethrin and temephos-resistant Ae. aegypti revealed diverse differentially expressed proteins associated with insecticide resistance from Penang Island, Malaysia

Abubakar Shettima, Intan Haslina Ishak, Benjamin Lau, Hadura Abu Hasan, Noorizan Miswan, Nurulhasanah Othman

PLOS Neglected Tropical Diseases: published September 18, 2023 | https://doi.org/10.1371/journal.pntd.0011604

Extensive genetic diversity of severe fever with thrombocytopenia syndrome virus circulating in Hubei Province, China, 2018–2022

Yu-ting Ren, Hong-pan Tian, Jia-le Xu, Man-qing Liu, Kun Cai, Shu-liang Chen, Xue-bing Ni, Yi-rong Li, Wei Hou, Liang-jun Chen

PLOS Neglected Tropical Diseases: published September 18, 2023 | https://doi.org/10.1371/journal.pntd.0011654

The seroprevalence of anti-Histoplasma capsulatum IgG antibody among pulmonary tuberculosis patients in seven referral tuberculosis hospitals in Indonesia

Tutik Kusmiati, Erlina Burhan, Retna Indah Sugiyono, Dona Arlinda, Adhella Menur Naysilla, Banteng Hanang Wibisono, Riat El Khair, Ni Wayan Candrawati, Bintang Yinke Magdalena Sinaga, Irawaty Djaharrudin, Dewi Lokida, Herman Kosasih, Nugroho Harry Susanto, Deni Pepy Butar Butar, Robiatul Adawiyah, Ayu Eka Fatril, Muhammad Karyana, David W. Denning, Retno Wahyuningsih

PLOS Neglected Tropical Diseases: published September 20, 2023 | https://doi.org/10.1371/journal.pntd.0011575

Disruption of the inositol phosphorylceramide synthase gene affects Trypanosoma cruzi differentiation and infection capacity

Nailma S A Dos Santos, Carlos F. Estevez-Castro, Juan P. Macedo, Daniela F. Chame, Thiago Castro-Gomes, Mariana Santos-Cardoso, Gabriela A. Burle-Caldas, Courtney N. Covington, Patrick G. Steel, Terry K. Smith, Paul W. Denny, Santuza M. R. Teixeira

PLOS Neglected Tropical Diseases: published September 20, 2023 | https://doi.org/10.1371/journal.pntd.0011646

Effects of mating on female reproductive physiology in the insect model, Rhodnius prolixus, a vector of the causative parasite of Chagas disease

Jimena Leyria, Alessandra A. Guarneri, Marcelo G. Lorenzo, Marcela Nouzova, Fernando G. Noriega, Samiha A. M. Benrabaa, Francisco Fernandez-Lima, Lilian Valadares Tose, Ian Orchard, Angela B. Lange

PLOS Neglected Tropical Diseases: published September 20, 2023 | https://doi.org/10.1371/journal.pntd.0011640

Belgian Culex pipiens pipiens are competent vectors for West Nile virus while Culex modestus are competent vectors for Usutu virus

Alina Soto, Lander De Coninck, Ann-Sophie Devlies, Celine Van De Wiele, Ana Lucia Rosales Rosas, Lanjiao Wang, Jelle Matthijnssens, Leen Delang

PLOS Neglected Tropical Diseases: published September 20, 2023 | https://doi.org/10.1371/journal.pntd.0011649

Phlebotomine sand flies (Diptera, Psychodidae) from Pha Tong cave, Northern Thailand with a description of two new species and taxonomical thoughts about Phlebotomus stantoni

Marie-Charlotte Renaux Torres, Coline Pellot, Puckavadee Somwang, Pathamet Khositharattanakool, Khamsing Vongphayloth, Fano José Randrianambinintsoa, Bruno Mathieu, Padet Siriyasatien, Frédérick Gay, Jérôme Depaquit

PLOS Neglected Tropical Diseases: published September 20, 2023 | https://doi.org/10.1371/journal.pntd.0011565

The increasing complexity of arbovirus serology: An in-depth systematic review on cross-reactivity

Louella M. R. Kasbergen, David F. Nieuwenhuijse, Erwin de Bruin, Reina S. Sikkema, Marion P. G. Koopmans

PLOS Neglected Tropical Diseases: published September 22, 2023 | https://doi.org/10.1371/journal.pntd.0011651

Variable microbiomes between mosquito lines are maintained across different environments

Anastasia Accoti, Shannon Quek, Julia Vulcan, Cintia Cansado-Utrilla, Enyia R. Anderson, Angel Elma I. Abu, Jessica Alsing, Hema P. Narra, Kamil Khanipov, Grant L. Hughes, Laura B. Dickson

PLOS Neglected Tropical Diseases: published September 25, 2023 | https://doi.org/10.1371/journal.pntd.0011306

Knowledge, attitude and practice (KAP) and risk factors on dengue fever among children in Brazil, Fortaleza: A cross-sectional study

Yang Zhang, Monica Zahreddine, Kellyanne Abreu, Mayana Azevedo Dantas, Katia Charland, Laura Pierce, Valéry Ridde, Kate Zinszer

PLOS Neglected Tropical Diseases: published September 25, 2023 | https://doi.org/10.1371/journal.pntd.0011110

Geographical distribution of scrub typhus and risk of Orientia tsutsugamushi infection in Indonesia: Evidence mapping

Kartika Saraswati, Ivo Elliott, Nicholas P. J. Day, J. Kevin Baird, Stuart D. Blacksell, Ristiyanto, Catherine L. Moyes

PLOS Neglected Tropical Diseases: published September 25, 2023 | https://doi.org/10.1371/journal.pntd.0011412

Prevalence and intensity of soil-transmitted helminth infections in Uganda: Results from population-based prevalence surveys in five districts

Benjamin Tinkitina, Prudence Beinamaryo, Moses Adriko, Betty Nabatte, Moses Arinaitwe, Alfred Mubangizi, Paul Emerson, Sanjaya Dhakal, Kristin M. Sullivan

PLOS Neglected Tropical Diseases: published September 26, 2023 | https://doi.org/10.1371/journal.pntd.0011605

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PLOS Neglected Tropical Diseases: published September 29, 2023 | https://doi.org/10.1371/journal.pntd.0011626

Gestational toxoplasmosis treatment changes the child’s prognosis: A cohort study in southern Brazil

Ana Gabriela Gomes Ferrari Strang, Rafaela Gomes Ferrar, Ana Lúcia Falavigna-Guilherme

PLOS Neglected Tropical Diseases: published September 29, 2023 | https://doi.org/10.1371/journal.pntd.0011544

Correction

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