Culex quinquefasciatus has a relevant role in the transmission of diseases of importance to veterinary and human health. Larvae feed on several microorganisms, including microalgae. One of them, identified as Neochloris aquatica, was isolated from an artificial breeding site where there were no immature stages of mosquitoes. Although it is chosen by gravid females to lay their eggs, the microalga had a negative effect on the development of larvae. Additionally, when the larvae were fed with a culture of alga supplemented with balanced food, they were not able to reverse its effect, and were unable to complete development until adulthood. [Gil, et al. (2021), Culex quinquefasciatus larvae development arrested when fed on Neochloris aquatica
Image Credit: M Florencia Gil
Policy Platform
Safely resuming neglected tropical disease control activities during COVID-19: Perspectives from Nigeria and Guinea
Stephanie McKay, Joy Shu’aibu, Abdourahim Cissé, Albi Knight, Fadhalu Abdullahi, Ahmed Ibrahim, Suzie Madaki, Chantelle Genovezos, Kate McCoy, Philip Downs, Achille Kabore, Helen Adamu, Ibrahim B. Gobir, Michael Chaitkin, Claire J. Standley
PLOS Neglected Tropical Diseases: published December 20, 2021 | https://doi.org/10.1371/journal.pntd.0009904
Symposium
Lateral flow devices for samples collected by straw sampling method for postmortem canine rabies diagnosis
Milagros R. Mananggit, Daria L. Manalo, Nobuo Saito, Kazunori Kimitsuki, Alyssa Marie G. Garcia, Patricia Mae T. Lacanilao, Joely T. Ongtangco, Cornhlo R. Velasco, Maria Victoria A. del Rosario, Maria Glofezita O. Lagayan, Kentaro Yamada, Chun-Ho Park, Satoshi Inoue, Motoi Suzuki, Mariko Saito-Obata, Yasuhiko Kamiya, Catalino S. Demetria, Beatriz P. Quiambao, Akira Nishizono
PLOS Neglected Tropical Diseases: published December 9, 2021 | https://doi.org/10.1371/journal.pntd.0009891
Reviews
Terrestrial venomous animals, the envenomings they cause, and treatment perspectives in the Middle East and North Africa
Timothy P. Jenkins, Shirin Ahmadi, Matyas A. Bittenbinder, Trenton K. Stewart, Dilber E. Akgun, Melissa Hale, Nafiseh N. Nasrabadi, Darian S. Wolff, Freek J. Vonk, Jeroen Kool, Andreas H. Laustsen
PLOS Neglected Tropical Diseases: published December 2, 2021 | https://doi.org/10.1371/journal.pntd.0009880
Experimental human hookworm infection: a narrative historical review
Paul R. Chapman, Paul Giacomin, Alex Loukas, James S. McCarthy
PLOS Neglected Tropical Diseases: published December 9, 2021 | https://doi.org/10.1371/journal.pntd.0009908
Roadblocks in Chagas disease care in endemic and nonendemic countries: Argentina, Colombia, Spain, and the United States. The NET-Heart project
Andrés F. Miranda-Arboleda, Ezequiel José Zaidel, Rachel Marcus, María Jesús Pinazo, Luis Eduardo Echeverría, Clara Saldarriaga, Álvaro Sosa Liprandi, Adrián Baranchuk, on behalf of the Neglected Tropical Diseases and other Infectious Diseases affecting the Heart (NET-Heart) project
PLOS Neglected Tropical Diseases: published December 30, 2021 | https://doi.org/10.1371/journal.pntd.0009954
Research Articles
Biogeography and genetic diversity of clinical isolates of Burkholderia pseudomallei in Sri Lanka
Himali S. Jayasinghearachchi, Enoka M. Corea, Kumari I. Jayaratne, Regina A. Fonseka, Thilini A. Muthugama, Jayanthi Masakorala, Ravija YC. Ramasinghe, Aruna D. De Silva
PLOS Neglected Tropical Diseases: published December 1, 2021 | https://doi.org/10.1371/journal.pntd.0009917
What is the impact of acquired immunity on the transmission of schistosomiasis and the efficacy of current and planned mass drug administration programmes?
Klodeta Kura, Robert J. Hardwick, James E. Truscott, Roy M. Anderson
PLOS Neglected Tropical Diseases: published December 1, 2021 | https://doi.org/10.1371/journal.pntd.0009946
Evidence of Chikungunya virus seroprevalence in Myanmar among dengue-suspected patients and healthy volunteers in 2013, 2015, and 2018
Elizabeth Ajema Chebichi Luvai, Aung Kyaw Kyaw, Nundu Sabiti Sabin, Fuxun Yu, Saw Wut Hmone, Kyaw Zin Thant, Shingo Inoue, Kouichi Morita, Mya Myat Ngwe Tun
PLOS Neglected Tropical Diseases: published December 1, 2021 | https://doi.org/10.1371/journal.pntd.0009961
Immune responses in multiple hosts to Nucleocapsid Protein (NP) of Crimean-Congo Hemorrhagic Fever Virus (CCHFV)
Elif Karaaslan, Nesibe Selma Çetin, Merve Kalkan-Yazıcı, Sevde Hasanoğlu, Faruk Karakeçili, Aykut Özdarendeli, Ahmet Kalkan, Ali Osman Kılıç, Mehmet Ziya Doymaz
PLOS Neglected Tropical Diseases: published December 1, 2021 | https://doi.org/10.1371/journal.pntd.0009973
Current characteristics of animal rabies cases in Thailand and relevant risk factors identified by a spatial modeling approach
Weerapong Thanapongtharm, Sarin Suwanpakdee, Arun Chumkaeo, Marius Gilbert, Anuwat Wiratsudakul
PLOS Neglected Tropical Diseases: published December 1, 2021 | https://doi.org/10.1371/journal.pntd.0009980
Morbidity associated with Schistosoma mansoni infection in north-eastern Democratic Republic of the Congo
Maurice M. Nigo, Peter Odermatt, David Wully Nigo, Georgette B. Salieb-Beugelaar, Manuel Battegay, Patrick R. Hunziker
PLOS Neglected Tropical Diseases: published December 2, 2021 | https://doi.org/10.1371/journal.pntd.0009375
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Epidemiology of Schistosoma mansoni infection in Ituri Province, north-eastern Democratic Republic of the Congo
Maurice M. Nigo, Peter Odermatt, Georgette B. Salieb–Beugelaar, Oleksii Morozov, Manuel Battegay, Patrick R. Hunziker
PLOS Neglected Tropical Diseases: published December 2, 2021 | https://doi.org/10.1371/journal.pntd.0009486
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PLOS Neglected Tropical Diseases: published December 2, 2021 | https://doi.org/10.1371/journal.pntd.0009922
Rapid establishment of a frontline field laboratory in response to an imported outbreak of Ebola virus disease in western Uganda, June 2019
Amy J. Schuh, Jackson Kyondo, James Graziano, Stephen Balinandi, Markus H. Kainulainen, Alex Tumusiime, Luke Nyakarahuka, Sophia Mulei, Jimmy Baluku, William Lonergan, Oren Mayer, Rastus Masereka, Fredrick Masereka, Esther Businge, Alphonse Gatare, Loice Kabyanga, Samuel Muhindo, Raymond Mugabe, Issa Makumbi, Joshua Kayiwa, Milton Makoba Wetaka, Vance Brown, Joseph Ojwang, Lisa Nelson, Monica Millard, Stuart T. Nichol, Joel M. Montgomery, Celine H. Taboy, Julius J. Lutwama, John D. Klena
PLOS Neglected Tropical Diseases: published December 3, 2021 | https://doi.org/10.1371/journal.pntd.0009967
The feasibility of field collected pig oronasal secretions as specimens for the virologic surveillance of Japanese encephalitis virus
Shyan-Song Chiou, Jo-Mei Chen, Yi-Ying Chen, Min-Yuan Chia, Yi-Chin Fan
PLOS Neglected Tropical Diseases: published December 3, 2021 | https://doi.org/10.1371/journal.pntd.0009977
Culex quinquefasciatus larvae development arrested when fed on Neochloris aquatica
M. Florencia Gil, Marisol Fassolari, Marina E. Battaglia, Corina M. Berón
PLOS Neglected Tropical Diseases: published December 3, 2021 | https://doi.org/10.1371/journal.pntd.0009988
Spatial analysis of G.f.fuscipes abundance in Uganda using Poisson and Zero-Inflated Poisson regression models
Albert Mugenyi, Dennis Muhanguzi, Guy Hendrickx, Gaëlle Nicolas, Charles Waiswa, Steve Torr, Susan Christina Welburn, Peter M. Atkinson
PLOS Neglected Tropical Diseases: published December 6, 2021 | https://doi.org/10.1371/journal.pntd.0009820
Assessment of community support for Wolbachia-mediated population suppression as a control method for Aedes aegypti mosquitoes in a community cohort in Puerto Rico
Liliana Sánchez-González, Laura E. Adams, Rafael Saavedra, Emma M. Little, Nicole A. Medina, Chelsea G. Major, Marina Bruck, Julieanne Miranda, Coral Rosado-Santiago, Kyle Ryff, Marianyoly Ortiz, Grayson Brown, Roberto Barrera, Carmen L. Pérez-Guerra, Vanessa Rivera-Amill, Gabriela Paz-Bailey
PLOS Neglected Tropical Diseases: published December 6, 2021 | https://doi.org/10.1371/journal.pntd.0009966
Left ventricular systolic dysfunction predicted by artificial intelligence using the electrocardiogram in Chagas disease patients–The SaMi-Trop cohort
Bruno Oliveira de Figueiredo Brito, Zachi I. Attia, Larissa Natany A. Martins, Pablo Perel, Maria Carmo P. Nunes, Ester Cerdeira Sabino, Clareci Silva Cardoso, Ariela Mota Ferreira, Paulo R. Gomes, Antonio Luiz Pinho Ribeiro, Francisco Lopez-Jimenez
PLOS Neglected Tropical Diseases: published December 6, 2021 | https://doi.org/10.1371/journal.pntd.0009974
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Hannes Vietzen, Svenja Hartenberger, Stephan W. Aberle, Elisabeth Puchhammer-Stöckl
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Serum and urinary biomarkers for early detection of acute kidney injury following Hypnale spp. envenoming
Eranga Sanjeewa Wijewickrama, Fahim Mohamed, Indika B. Gawarammana, Zoltan H. Endre, Nicholas A. Buckley, Geoffrey K. Isbister
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Sero-prevalence of anti-Leptospira antibodies and associated risk factors in rural Rwanda: A cross-sectional study
Etienne Ntabanganyimana, Robert Giraneza, Vincent Dusabejambo, Appolinaire Bizimana, Camila Hamond, Augustin Iyamuremye, Placide Nshizirungu, Raphael Uzabakiriho, Marc Munyengabe, Elsio A. Wunder Jr., Cameron Page
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A ten-year review of neonatal tetanus cases managed at a tertiary health facility in a resource poor setting: The trend, management challenges and outcome
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Very high prevalence of infection with the human T cell leukaemia virus type 1c in remote Australian Aboriginal communities: Results of a large cross-sectional community survey
Lloyd Einsiedel, Hai Pham, Mohammad Radwanur Talukder, Kerry Taylor, Kim Wilson, John Kaldor, Antoine Gessain, Richard Woodman
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A MEKK1 – JNK mitogen activated kinase (MAPK) cascade module is active in Echinococcus multilocularis stem cells
Kristin Stoll, Monika Bergmann, Markus Spiliotis, Klaus Brehm
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Deep resequencing identifies candidate functional genes in leprosy GWAS loci
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Factors associated with the unwillingness of Jordanians, Palestinians and Syrians to be vaccinated against COVID-19
Sima Zein, Sarah B. Abdallah, Ahmed Al-Smadi, Omar Gammoh, Wajdy J. Al-Awaida, Hanan J. Al-Zein
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Diagnosis of Taenia solium infections based on "mail order" RNA-sequencing of single tapeworm egg isolates from stool samples
Henrik Sadlowski, Veronika Schmidt, Jonathan Hiss, Johannes A. Kuehn, Christian G. Schneider, Gideon Zulu, Alex Hachangu, Chummy S. Sikasunge, Kabemba E. Mwape, Andrea S. Winkler, Markus Schuelke
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Canine leishmaniosis in Tunisia: Growing prevalence, larger zones of infection
Ali Bouattour, Amine Amri, Jaber Amine Belkhiria, Adel Rhim, Ons Fezaa, Jean-Charles Gantier, Youmna M’ghirbi
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Clinical epidemiological characteristics of mycetoma in Eastern Sennar locality, Sennar State, Sudan
Rowa Hassan, Kebede Deribe, Ahmed Hassan Fahal, Melanie Newport, Sahar Bakhiet
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First evaluation of antibody responses to Culex quinquefasciatus salivary antigens as a serological biomarker of human exposure to Culex bites: A pilot study in Côte d’Ivoire
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An age-stratified serosurvey against purified Salmonella enterica serovar Typhi antigens in the Lao People ́s Democratic Republic
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Leprosy and cutaneous leishmaniasis affecting the same individuals: A retrospective cohort analysis in a hyperendemic area in Brazil
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Treponema pallidum genome sequencing from six continents reveals variability in vaccine candidate genes and dominance of Nichols clade strains in Madagascar
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PLOS Neglected Tropical Diseases: published December 22, 2021 | https://doi.org/10.1371/journal.pntd.0010063
Morphological and genomic characterisation of the Schistosoma hybrid infecting humans in Europe reveals admixture between Schistosoma haematobium and Schistosoma bovis
Julien Kincaid-Smith, Alan Tracey, Ronaldo de Carvalho Augusto, Ingo Bulla, Nancy Holroyd, Anne Rognon, Olivier Rey, Cristian Chaparro, Ana Oleaga, Santiago Mas-Coma, Jean-François Allienne, Christoph Grunau, Matthew Berriman, Jérôme Boissier, Eve Toulza
PLOS Neglected Tropical Diseases: published December 23, 2021 | https://doi.org/10.1371/journal.pntd.0010062
Prevalence and spatial distribution characteristics of human echinococcosis in China
Li-Ying Wang, Min Qin, Ze-Hang Liu, Wei-Ping Wu, Ning Xiao, Xiao-Nong Zhou, Sylvie Manguin, Laurent Gavotte, Roger Frutos
PLOS Neglected Tropical Diseases: published December 28, 2021 | https://doi.org/10.1371/journal.pntd.0009996
Molecular and epidemiological characterization of recurrent Mycobacterium ulcerans infections in Benin
Ronald Gnimavo, Alban Besnard, Horace Degnonvi, Juliana Pipoli Da Fonseca, Marie Kempf, Christian Roch Johnson, Alexandra Boccarossa, Yao Télesphore Brou, Laurent Marsollier, Estelle Marion
PLOS Neglected Tropical Diseases: published December 28, 2021 | https://doi.org/10.1371/journal.pntd.0010053
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