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Table of Contents

April 2021

Dogs are good partners for people in Zambia the same as in most other countries. Therefore, control of zoonoses that can be shared among humans and dogs, such as rabies, is an important issue for both public health and animal health. Vaccination of dogs is one of the key measures for controlling rabies in humans and dogs. Kaneko (2021)

Image Credit: Chiho Kaneko

Viewpoints

Alternative approaches to lymphoedema care in lymphatic filariasis

Suma Krishnasastry, Charles D. Mackenzie

PLOS Neglected Tropical Diseases: published April 29, 2021 | https://doi.org/10.1371/journal.pntd.0009293

Reviews

The application of spectroscopy techniques for diagnosis of malaria parasites and arboviruses and surveillance of mosquito vectors: A systematic review and critical appraisal of evidence

Brendon Goh, Koek Ching, Ricardo J. Soares Magalhães, Silvia Ciocchetta, Michael D. Edstein, Rafael Maciel-de-Freitas, Maggy T. Sikulu-Lord

PLOS Neglected Tropical Diseases: published April 22, 2021 | https://doi.org/10.1371/journal.pntd.0009218

Reviewing the ecological evidence base for management of emerging tropical zoonoses: Kyasanur Forest Disease in India as a case study

Sarah J. Burthe, Stefanie M. Schäfer, Festus A. Asaaga, Natrajan Balakrishnan, Mohammed Mudasssar Chanda, Narayanaswamy Darshan, Subhash L. Hoti, Shivani K. Kiran, Tanya Seshadri, Prashanth N. Srinivas, Abi T. Vanak, Bethan V. Purse

PLOS Neglected Tropical Diseases: published April 1, 2021 | https://doi.org/10.1371/journal.pntd.0009243

Research Articles

Combining natural language processing and metabarcoding to reveal pathogen-environment associations

David C. Molik, DeAndre Tomlinson, Shane Davitt, Eric L. Morgan, Matthew Sisk, Benjamin Roche, Natalie Meyers, Michael E. Pfrender

PLOS Neglected Tropical Diseases: published April 7, 2021 | https://doi.org/10.1371/journal.pntd.0008755

New traps for the capture of Aedes aegypti (Linnaeus) and Aedes albopictus (Skuse) (Diptera: Culicidae) eggs and adults

Karina Rossi da Silva, William Ribeiro da Silva, Bianca Piraccini Silva, Adriano Nobre Arcos, Francisco Augusto da Silva Ferreira, Joelma Soares-da-Silva, Grafe Oliveira Pontes, Rosemary Aparecida Roque, Wanderli Pedro Tadei, Mário Antonio Navarro-Silva, João Antonio Cyrino Zequi

PLOS Neglected Tropical Diseases: published April 16, 2021 | https://doi.org/10.1371/journal.pntd.0008813

How geographic access to care shapes disease burden: The current impact of post-exposure prophylaxis and potential for expanded access to prevent human rabies deaths in Madagascar

Malavika Rajeev, Hélène Guis, Glenn Torrencelli Edosoa, Chantal Hanitriniaina, Anjasoa Randrianarijaona, Reziky Tiandraza Mangahasimbola, Fleur Hierink, Ravo Ramiandrasoa, José Nely, Jean-Michel Heraud, Soa Fy Andriamandimby, Laurence Baril, C. Jessica E. Metcalf, Katie Hampson

PLOS Neglected Tropical Diseases: published April 26, 2021 | https://doi.org/10.1371/journal.pntd.0008821

Distinguishing non severe cases of dengue from COVID-19 in the context of co-epidemics: A cohort study in a SARS-CoV-2 testing center on Reunion island

Antoine Joubert, Fanny Andry, Antoine Bertolotti, Frédéric Accot, Yatrika Koumar, Florian Legrand, Patrice Poubeau, Rodolphe Manaquin, Patrick Gérardin, Cécile Levin

PLOS Neglected Tropical Diseases: published April 26, 2021 | https://doi.org/10.1371/journal.pntd.0008879

Fat tissue regulates the pathogenesis and severity of cardiomyopathy in murine chagas disease

Kezia Lizardo, Janeesh P. Ayyappan, Neelam Oswal, Louis M. Weiss, Philipp E. Scherer, Jyothi F. Nagajyothi

PLOS Neglected Tropical Diseases: published April 7, 2021 | https://doi.org/10.1371/journal.pntd.0008964

Epidemiological and clinical characteristics of severe fever with thrombocytopenia syndrome bunyavirus human-to-human transmission

Xinyu Fang, Jianli Hu, Zhihang Peng, Qigang Dai, Wendong Liu, Shuyi Liang, Zhifeng Li, Nan Zhang, Changjun Bao

PLOS Neglected Tropical Diseases: published April 30, 2021 | https://doi.org/10.1371/journal.pntd.0009037

Tick-borne relapsing fever Borreliosis, a major public health problem overlooked in Senegal

El Hadji Ibrahima Ndiaye, Fatou Samba Diouf, Mady Ndiaye, Hubert Bassene, Didier Raoult, Cheikh Sokhna, Philippe Parola, Georges Diatta

PLOS Neglected Tropical Diseases: published April 22, 2021 | https://doi.org/10.1371/journal.pntd.0009184

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Secreted Wnt antagonists in scrub typhus

Thor Ueland, Elisabeth Astrup, Kari Otterdal, Tove Lekva, Jeshina Janardhanan, John A. J. Prakash, Kurien Thomas, Annika E. Michelsen, Pål Aukrust, George M. Varghese, Jan K. Damås

PLOS Neglected Tropical Diseases: published April 29, 2021 | https://doi.org/10.1371/journal.pntd.0009185

Domestic dog demographics and estimates of canine vaccination coverage in a rural area of Zambia for the elimination of rabies

Chiho Kaneko, Ryosuke Omori, Michihito Sasaki, Chikako Kataoka-Nakamura, Edgar Simulundu, Walter Muleya, Ladslav Moonga, Joseph Ndebe, Bernard M. Hang’ombe, George Dautu, Yongjin Qiu, Ryo Nakao, Masahiro Kajihara, Akina Mori-Kajihara, Herman M. Chambaro, Hideaki Higashi, Chihiro Sugimoto, Hirofumi Sawa, Aaron S. Mweene, Ayato Takada, Norikazu Isoda

PLOS Neglected Tropical Diseases: published April 28, 2021 | https://doi.org/10.1371/journal.pntd.0009222

Crimean-Congo hemorrhagic fever virus antibody prevalence in Mauritanian livestock (cattle, goats, sheep and camels) is stratified by the animal’s age

Ansgar Schulz, Yahya Barry, Franziska Stoek, Aliou Ba, Jana Schulz, Mohamed L. Haki, Miriam A. Sas, Baba A. Doumbia, Peter Kirkland, Mohamed Y. Bah, Martin Eiden, Martin H. Groschup

PLOS Neglected Tropical Diseases: published April 12, 2021 | https://doi.org/10.1371/journal.pntd.0009228

Seroprevalence of chikungunya virus infection among HIV-infected adults in French Caribbean Islands of Martinique and Guadeloupe in 2015: A cross-sectional study

Elodie Curlier, Laurence Fagour, Cécile Herrmann-Storck, Adrien Staelen, Ingrid Vingadassalom, Sébastien Breurec, Sylvie Abel, Sandrine Pierre-François, Janick Jean-Marie, Cédric Laouénan, Raymond Césaire, Bruno Hoen, André Cabié

PLOS Neglected Tropical Diseases: published April 9, 2021 | https://doi.org/10.1371/journal.pntd.0009267

Meta-analysis of the prevalence of Echinococcus in dogs in China from 2010 to 2019

Qing-Long Gong, Gui-Yang Ge, Qi Wang, Tian Tian, Fei Liu, Nai-Chao Diao, Lan-Bi Nie, Ying Zong, Jian-Ming Li, Kun Shi, Xue Leng, Rui Du

PLOS Neglected Tropical Diseases: published April 2, 2021 | https://doi.org/10.1371/journal.pntd.0009268

Drug reformulation for a neglected disease. The NANOHAT project to develop a safer more effective sleeping sickness drug

Lisa Sanderson, Marcelo da Silva, Gayathri N. Sekhar, Rachel C. Brown, Hollie Burrell-Saward, Mehmet Fidanboylu, Bo Liu, Lea Ann Dailey, Cécile A. Dreiss, Chris Lorenz, Mark Christie, Shanta J. Persaud, Vanessa Yardley, Simon L. Croft, Margarita Valero, Sarah A. Thomas

PLOS Neglected Tropical Diseases: published April 15, 2021 | https://doi.org/10.1371/journal.pntd.0009276

Routine deworming during antenatal care decreases risk of neonatal mortality and low birthweight: A retrospective cohort of survey data

Bhavneet Walia, Brittany L. Kmush, Sandra D. Lane, Timothy Endy, Antonio Montresor, David A. Larsen

PLOS Neglected Tropical Diseases: published April 29, 2021 | https://doi.org/10.1371/journal.pntd.0009282

Basement membrane proteins as a substrate for efficient Trypanosoma brucei differentiation in vitro

Federico Rojas, Mathieu Cayla, Keith R. Matthews

PLOS Neglected Tropical Diseases: published April 28, 2021 | https://doi.org/10.1371/journal.pntd.0009284

High prevalence and mortality due to Histoplasma capsulatum in the Brazilian Amazon: An autopsy study

Natalia Rakislova, Juan Carlos Hurtado, Antonio E. M. Palhares, Luiz Ferreira, Monique Freire, Marcus Lacerda, Wuelton Monteiro, Mireia Navarro, Isaac Casas, Marcus de Melo Teixeira, Paola Castillo, Maria Teresa Rodrigo-Calvo, Lorena Marimon, José Guerrero, Rosauro Varo, Vima Delgado, Llorenç Quintó, Francesc Marco, Emilio Letang, Jordi Vila, Quique Bassat, Clara Menéndez, Jaume Ordi, Miguel J. Martínez

PLOS Neglected Tropical Diseases: published April 5, 2021 | https://doi.org/10.1371/journal.pntd.0009286

Microsatellite based molecular epidemiology of Leishmania infantum from re-emerging foci of visceral leishmaniasis in Armenia and pilot risk assessment by ecological niche modeling

Katrin Kuhls, Olga Moskalenko, Anna Sukiasyan, Dezdemonia Manukyan, Gayane Melik-Andreasyan, Liana Atshemyan, Hripsime Apresyan, Margarita Strelkova, Anja Jaeschke, Ralf Wieland, Marcus Frohme, Sofia Cortes, Ara Keshishyan

PLOS Neglected Tropical Diseases: published April 19, 2021 | https://doi.org/10.1371/journal.pntd.0009288

Seroprevalence of Chikungunya virus and living conditions in Feira de Santana, Bahia-Brazil

Maria Glória Teixeira, Lacita Menezes Skalinski, Enny S. Paixão, Maria da Conceição N. Costa, Florisneide Rodrigues Barreto, Gubio Soares Campos, Silvia Ines Sardi, Rejane Hughes Carvalho, Marcio Natividade, Martha Itaparica, Juarez Pereira Dias, Soraya Castro Trindade, Bárbara Pereira Teixeira, Vanessa Morato, Eloisa Bahia Santana, Cristina Borges Goes, Neuza Santos de Jesus Silva, Carlos Antonio de Souza Teles Santos, Laura C. Rodrigues, Jimmy Whitworth

PLOS Neglected Tropical Diseases: published April 20, 2021 | https://doi.org/10.1371/journal.pntd.0009289

Short report: Introduction of chikungunya virus ECSA genotype into the Brazilian Midwest and its dispersion through the Americas

Elaine Cristina de Oliveira, Vagner Fonseca, Joilson Xavier, Talita Adelino, Ingra Morales Claro, Allison Fabri, Eduardo Marques Macario, Ana Elisa Viniski, Claudio Luis Campos Souza, Evanil Sebastiana Gomes da Costa, Claudia Soares de Sousa, Flávia Guimarães Dias Duarte, Arnaldo Correia de Medeiros, Carlos F. Campelo de Albuquerque, Rivaldo Venancio Cunha, Noely Fabiana Oliveira De Moura, Ana Maria Bispo de Filippis, Tulio de Oliveira, José Lourenço, André Luiz de Abreu, Luiz Carlos Junior Alcantara, Marta Giovanetti

PLOS Neglected Tropical Diseases: published April 16, 2021 | https://doi.org/10.1371/journal.pntd.0009290

Diagnostic performance of a Recombinant Polymerase Amplification Test—Lateral Flow (RPA-LF) for cutaneous leishmaniasis in an endemic setting of Colombia

Alexandra Cossio, Jimena Jojoa, María del Mar Castro, Ruth Mabel Castillo, Lyda Osorio, Thomas R. Shelite, Nancy Gore Saravia, Peter C. Melby, Bruno L. Travi

PLOS Neglected Tropical Diseases: published April 28, 2021 | https://doi.org/10.1371/journal.pntd.0009291

Changes in inflammatory gene expression in brain tissue adjacent and distant to a viable cyst in a rat model for neurocysticercosis

Rogger P. Carmen-Orozco, Danitza G. Dávila-Villacorta, Ana D. Delgado-Kamiche, Rensson H. Celiz, Grace Trompeter, Graham Sutherland, Cesar Gavídia, Hector H. Garcia, Robert H. Gilman, Manuela R. Verástegui, for the Cysticercosis Working Group in Peru

PLOS Neglected Tropical Diseases: published April 27, 2021 | https://doi.org/10.1371/journal.pntd.0009295

‘The medicine is not for sale’: Practices of traditional healers in snakebite envenoming in Ghana

Jonathan Steinhorst, Leslie Mawuli Aglanu, Sofanne J. Ravensbergen, Chrisantus Danaah Dari, Kabiru Mohammed Abass, Samuel Osei Mireku, Joseph Ken Adu Poku, Yeetey A. K. Enuameh, Jörg Blessmann, Robert A. Harrison, John H. Amuasi, Ymkje Stienstra

PLOS Neglected Tropical Diseases: published April 16, 2021 | https://doi.org/10.1371/journal.pntd.0009298

Worldwide epidemiology of Crimean-Congo Hemorrhagic Fever Virus in humans, ticks and other animal species, a systematic review and meta-analysis

Jean Thierry Ebogo Belobo, Sebastien Kenmoe, Cyprien Kengne-Nde, Cynthia Paola Demeni Emoh, Arnol Bowo-Ngandji, Serges Tchatchouang, Jocelyne Noel Sowe Wobessi, Chris Andre Mbongue Mikangue, Hervé Raoul Tazokong, Sandrine Rachel Kingue Bebey, Efietngab Atembeh Noura, Aude Christelle Ka’e, Raïssa Estelle Guiamdjo Simo, Abdou Fatawou Modiyinji, Dimitri Tchami Ngongang, Emmanuel Che, Sorel Kenfack, Nathalie Diane Nzukui, Nathalie Amvongo Adjia, Isabelle Tatiana Babassagana, Gadji Mahamat, Donatien Serge Mbaga, Wilfred Fon Mbacham, Serge Alain Sadeuh-Mbah, Richard Njouom

PLOS Neglected Tropical Diseases: published April 22, 2021 | https://doi.org/10.1371/journal.pntd.0009299

Extracellular vesicles secreted by Giardia duodenalis regulate host cell innate immunity via TLR2 and NLRP3 inflammasome signaling pathways

Panpan Zhao, Lili Cao, Xiaocen Wang, Jingquan Dong, Nan Zhang, Xin Li, Jianhua Li, Xichen Zhang, Pengtao Gong

PLOS Neglected Tropical Diseases: published April 2, 2021 | https://doi.org/10.1371/journal.pntd.0009304

Potential for community based surveillance of febrile diseases: Feasibility of self-administered rapid diagnostic tests in Iquitos, Peru and Phnom Penh, Cambodia

Amy C. Morrison, Julia Schwarz, Jennie L. Mckenney, Jhonny Cordova, Jennifer E. Rios, W. Lorena Quiroz, S. Alfonso Vizcarra, Heng Sopheab, Karin M. Bauer, Chhorvann Chhea, Vonthanak Saphonn, Robert D. Hontz, Pamina M. Gorbach, Valerie A. Paz-Soldan

PLOS Neglected Tropical Diseases: published April 26, 2021 | https://doi.org/10.1371/journal.pntd.0009307

Non-replicating adenovirus based Mayaro virus vaccine elicits protective immune responses and cross protects against other alphaviruses

John M. Powers, Nicole N. Haese, Michael Denton, Takeshi Ando, Craig Kreklywich, Kiley Bonin, Cassilyn E. Streblow, Nicholas Kreklywich, Patricia Smith, Rebecca Broeckel, Victor DeFilippis, Thomas E. Morrison, Mark T. Heise, Daniel N. Streblow

PLOS Neglected Tropical Diseases: published April 1, 2021 | https://doi.org/10.1371/journal.pntd.0009308

Estimating true prevalence of Schistosoma mansoni from population summary measures based on the Kato-Katz diagnostic technique

Oliver Bärenbold, Amadou Garba, Daniel G. Colley, Fiona M. Fleming, Rufin K. Assaré, Edridah M. Tukahebwa, Biruck Kebede, Jean T. Coulibaly, Eliézer K. N’Goran, Louis-Albert Tchuem Tchuenté, Pauline Mwinzi, Jürg Utzinger, Penelope Vounatsou

PLOS Neglected Tropical Diseases: published April 5, 2021 | https://doi.org/10.1371/journal.pntd.0009310

Simultaneous circulation of two West Nile virus lineage 2 clades and Bagaza virus in the Zambezi region, Namibia

Heiko D. Guggemos, Matthias Fendt, Christian Hieke, Verena Heyde, John K. E. Mfune, Christian Borgemeister, Sandra Junglen

PLOS Neglected Tropical Diseases: published April 2, 2021 | https://doi.org/10.1371/journal.pntd.0009311

Use of seroprevalence to guide dengue vaccination plans for older adults in a dengue non-endemic country

Yi-Hua Pan, Mei-Ying Liao, Yu-Wen Chien, Tzong-Shiann Ho, Hui-Ying Ko, Chin-Rur Yang, Shu-Fen Chang, Chia-Yi Yu, Shu-Yu Lin, Pin-Wei Shih, Pei-Yun Shu, Day-Yu Chao, Chao-Ying Pan, Hong-Ming Chen, Guey-Chuen Perng, Chia-Chi Ku, Chwan-Chuen King

PLOS Neglected Tropical Diseases: published April 1, 2021 | https://doi.org/10.1371/journal.pntd.0009312

Preventive chemotherapy for the control of strongyloidiasis in school-age children: Estimating the ivermectin need

Donal Bisanzio, Antonio Montresor, Michael French, Richard Reithinger, Paola Rodari, Zeno Bisoffi, Dora Buonfrate

PLOS Neglected Tropical Diseases: published April 15, 2021 | https://doi.org/10.1371/journal.pntd.0009314

Enhanced passive surveillance dengue infection among febrile children: Prevalence, co-infections and associated factors in Cameroon

Celine Nguefeu Nkenfou, Nadine Fainguem, Félicitée Dongmo-Nguefack, Laeticia Grace Yatchou, Joel Josephine Kadji Kameni, Elise Lobe Elong, Amidou Samie, William Estrin, Paul Ndombo Koki, Alexis Ndjolo

PLOS Neglected Tropical Diseases: published April 16, 2021 | https://doi.org/10.1371/journal.pntd.0009316

An update on the occurrence of Paracoccidioides species in the Midwest region, Brazil: Molecular epidemiology, clinical aspects and serological profile of patients from Mato Grosso do Sul State

Karine Mattos, Tiago Alexandre Cocio, Edilânia Gomes Araújo Chaves, Clayton Luiz Borges, James Venturini, Lídia Raquel de Carvalho, Rinaldo Poncio Mendes, Anamaria Mello Miranda Paniago, Simone Schneider Weber

PLOS Neglected Tropical Diseases: published April 7, 2021 | https://doi.org/10.1371/journal.pntd.0009317

Trichomonas vaginalis infection impairs anion secretion in vaginal epithelium

Jian-Bang Xu, Shen-Jiao Lu, Li-Jiao Ke, Zhuo-Er Qiu, Lei Chen, Hao-Li Zhang, Xi-Yuan Wang, Xiao-Fan Wei, Shuming He, Yun-Xin Zhu, Zhao-Rong Lun, Wen-Liang Zhou, Yi-Lin Zhang

PLOS Neglected Tropical Diseases: published April 16, 2021 | https://doi.org/10.1371/journal.pntd.0009319

Distinct transcriptional profiles of Leptospira borgpetersenii serovar Hardjo strains JB197 and HB203 cultured at different temperatures

Ellie J. Putz, Sathesh K. Sivasankaran, Luis G. V. Fernandes, Brian Brunelle, John D. Lippolis, David P. Alt, Darrell O. Bayles, Richard L. Hornsby, Jarlath E. Nally

PLOS Neglected Tropical Diseases: published April 7, 2021 | https://doi.org/10.1371/journal.pntd.0009320

Localized skin inflammation during cutaneous leishmaniasis drives a chronic, systemic IFN-γ signature

Camila Farias Amorim, Fernanda O. Novais, Ba T. Nguyen, Mauricio T. Nascimento, Jamile Lago, Alexsandro S. Lago, Lucas P. Carvalho, Daniel P. Beiting, Phillip Scott

PLOS Neglected Tropical Diseases: published April 1, 2021 | https://doi.org/10.1371/journal.pntd.0009321

Characterization and functional analysis of the proteins Prohibitin 1 and 2 in Trypanosoma cruzi

Ana K. Ibarrola-Vannucci, Luis M. De Pablos, Lissette Retana-Moreira, Alberto Cornet-Gomez, Teresa Cruz-Bustos, Alejandro G. Schijman, José L. Ramírez, Susana Vílchez, Antonio Osuna

PLOS Neglected Tropical Diseases: published April 8, 2021 | https://doi.org/10.1371/journal.pntd.0009322

A novel mechanism of streptomycin resistance in Yersinia pestis: Mutation in the rpsL gene

Ruixia Dai, Jian He, Xi Zha, Yiting Wang, Xuefei Zhang, He Gao, Xiaoyan Yang, Juan Li, Youquan Xin, Yumeng Wang, Sheng Li, Juan Jin, Qi Zhang, Jixiang Bai, Yao Peng, Hailian Wu, Qingwen Zhang, Baiqing Wei, Jianguo Xu, Wei Li

PLOS Neglected Tropical Diseases: published April 22, 2021 | https://doi.org/10.1371/journal.pntd.0009324

Deciphering the introduction and transmission of SARS-CoV-2 in the Colombian Amazon Basin

Nathalia Ballesteros, Marina Muñoz, Luz Helena Patiño, Carolina Hernández, Felipe González-Casabianca, Iván Carroll, Mauricio Santos-Vega, Jaime Cascante, Andrés Angel, Alejandro Feged-Rivadeneira, Mónica Palma-Cuero, Carolina Flórez, Sergio Gomez, Adriana van de Guchte, Zenab Khan, Jayeeta Dutta, Ajay Obla, Hala Alejel Alshammary, Ana S. Gonzalez-Reiche, Matthew M. Hernandez, Emilia Mia Sordillo, Viviana Simon, Harm van Bakel, Alberto E. Paniz-Mondolfi, Juan David Ramírez

PLOS Neglected Tropical Diseases: published April 15, 2021 | https://doi.org/10.1371/journal.pntd.0009327

Effect of maternal praziquantel treatment for Schistosoma japonicum infection on the offspring susceptibility and immunologic response to infection at age six, a cohort study

Susannah Colt, Blanca Jarilla, Palmera Baltazar, Veronica Tallo, Luz P. Acosta, Hannah W. Wu, Christopher V. Barry, Jonathan D. Kurtis, Remigio M. Olveda, Jennifer F. Friedman, Mario A. Jiz

PLOS Neglected Tropical Diseases: published April 16, 2021 | https://doi.org/10.1371/journal.pntd.0009328

Strengthening individual and family resilience against leprosy-related discrimination: A pilot intervention study

Anna T. van’t Noordende, Zoica Bakirtzief da Silva Pereira, Pritha Biswas, Mohammed Ilyas, Vijay Krishnan, Jayaram Parasa, Pim Kuipers

PLOS Neglected Tropical Diseases: published April 2, 2021 | https://doi.org/10.1371/journal.pntd.0009329

Control of scabies in a tribal community using mass screening and treatment with oral ivermectin -A cluster randomized controlled trial in Gadchiroli, India

Priyamadhaba Behera, Hrishikesh Munshi, Yogeshwar Kalkonde, Mahesh Deshmukh, Abhay Bang

PLOS Neglected Tropical Diseases: published April 16, 2021 | https://doi.org/10.1371/journal.pntd.0009330

An investigation of conventional microbial culture for the Naja atra bite wound, and the comparison between culture-based 16S Sanger sequencing and 16S metagenomics of the snake oropharyngeal bacterial microbiota

Yan-Chiao Mao, Han-Ni Chuang, Chien-Hung Shih, Han-Hsueh Hsieh, Yu-Han Jiang, Liao-Chun Chiang, Wen-Loung Lin, Tzu-Hung Hsiao, Po-Yu Liu

PLOS Neglected Tropical Diseases: published April 15, 2021 | https://doi.org/10.1371/journal.pntd.0009331

Development of an integrated, holistic care package for people with lymphoedema for use at the level of the Primary Health Care Unit in Ethiopia

Abraham Tesfaye, Maya Semrau, Oumer Ali, Mersha Kinfe, Mossie Tamiru, Abebaw Fekadu, Gail Davey

PLOS Neglected Tropical Diseases: published April 20, 2021 | https://doi.org/10.1371/journal.pntd.0009332

High prevalence of intestinal parasite infestations among stunted and control children aged 2 to 5 years old in two neighborhoods of Antananarivo, Madagascar

Azimdine Habib, Lova Andrianonimiadana, Maheninasy Rakotondrainipiana, Prisca Andriantsalama, Ravaka Randriamparany, Rindra Vatosoa Randremanana, Rado Rakotoarison, Inès Vigan-Womas, Armand Rafalimanantsoa, Pascale Vonaesch, Philippe J. Sansonetti, Jean-Marc Collard, the Afribiota Investigators

PLOS Neglected Tropical Diseases: published April 20, 2021 | https://doi.org/10.1371/journal.pntd.0009333

Aedes aegypti dyspepsia encodes a novel member of the SLC16 family of transporters and is critical for reproductive fitness

Hitoshi Tsujimoto, Michelle A. E. Anderson, Heather Eggleston, Kevin M. Myles, Zach N. Adelman

PLOS Neglected Tropical Diseases: published April 7, 2021 | https://doi.org/10.1371/journal.pntd.0009334

Genomic and epidemiological characteristics of SARS-CoV-2 in Africa

Jones Lamptey, Favour Oluwapelumi Oyelami, Michael Owusu, Bernard Nkrumah, Paul Oluwagbenga Idowu, Enoch Appiah Adu-Gyamfi, Armin Czika, Philip El-Duah, Richmond Yeboah, Augustina Sylverken, Oluwatayo Israel Olasunkanmi, Ellis Owusu-Dabo, Christian Drosten, Yaw Adu-Sarkodie

PLOS Neglected Tropical Diseases: published April 26, 2021 | https://doi.org/10.1371/journal.pntd.0009335

Diagnostic performance of anti-Zika virus IgM, IgAM and IgG ELISAs during co-circulation of Zika, dengue, and chikungunya viruses in Brazil and Venezuela

Ivonne Morales, Kerstin D. Rosenberger, Tereza Magalhaes, Clarice N. L. Morais, Cynthia Braga, Ernesto T. A. Marques, Guilherme Amaral Calvet, Luana Damasceno, Patricia Brasil, Ana Maria Bispo de Filippis, Adriana Tami, Sarah Bethencourt, Mayling Alvarez, Pedro A. Martínez, Maria G. Guzman, Bruno Souza Benevides, Andrea Caprara, Nguyen Than Ha Quyen, Cameron P. Simmons, Bridget Wills, Xavier de Lamballerie, Jan Felix Drexler, Thomas Jaenisch, the IDAMS Clinical Study Group

PLOS Neglected Tropical Diseases: published April 19, 2021 | https://doi.org/10.1371/journal.pntd.0009336

The worldwide seroprevalence of DENV, CHIKV and ZIKV infection: A systematic review and meta-analysis

Zhihui Li, Jin Wang, Xiaomin Cheng, Huan Hu, Cheng Guo, Jingyi Huang, Zeliang Chen, Jiahai Lu

PLOS Neglected Tropical Diseases: published April 28, 2021 | https://doi.org/10.1371/journal.pntd.0009337

Epidemiology of soil transmitted helminths and risk analysis of hookworm infections in the community: Results from the DeWorm3 Trial in southern India

Sitara S. R. Ajjampur, Saravanakumar Puthupalayam Kaliappan, Katherine E. Halliday, Gokila Palanisamy, Jasmine Farzana, Malathi Manuel, Dilip Abraham, Selvi Laxmanan, Kumudha Aruldas, Anuradha Rose, David S. Kennedy, William E. Oswald, Rachel L. Pullan, Sean R. Galagan, Kristjana Ásbjörnsdóttir, Roy M. Anderson, Jayaprakash Muliyil, Rajiv Sarkar, Gagandeep Kang, Judd L. Walson

PLOS Neglected Tropical Diseases: published April 30, 2021 | https://doi.org/10.1371/journal.pntd.0009338

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Orientia tsutsugamushi modulates cellular levels of NF-κB inhibitor p105

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PLOS Neglected Tropical Diseases: published April 15, 2021 | https://doi.org/10.1371/journal.pntd.0009339

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Michelle Odonkor, Fahd Naufal, Beatriz Munoz, Harran Mkocha, Mabula Kasubi, Meraf Wolle, Sheila West

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Spatiotemporal distribution of cutaneous leishmaniasis in Sri Lanka and future case burden estimates

Nadira D. Karunaweera, Sanath Senanayake, Samitha Ginige, Hermali Silva, Nuwani Manamperi, Nilakshi Samaranayake, Rajika Dewasurendra, Panduka Karunanayake, Deepa Gamage, Nissanka de Silva, Upul Senarath, Guofa Zhou

PLOS Neglected Tropical Diseases: published April 23, 2021 | https://doi.org/10.1371/journal.pntd.0009346

Natural infections of Pintomyia verrucarum and Pintomyia maranonensis by Leishmania (Viannia) peruviana in the Eastern Andes of northern Peru

Hirotomo Kato, Chisato Seki, Makoto Kubo, Lizandro Gonzales-Cornejo, Abraham G. Caceres

PLOS Neglected Tropical Diseases: published April 15, 2021 | https://doi.org/10.1371/journal.pntd.0009352

Serious adverse reactions associated with ivermectin: A systematic pharmacovigilance study in sub-Saharan Africa and in the rest of the World

Jérémy T. Campillo, Michel Boussinesq, Sébastien Bertout, Jean-Luc Faillie, Cédric B. Chesnais

PLOS Neglected Tropical Diseases: published April 20, 2021 | https://doi.org/10.1371/journal.pntd.0009354

Neglected human Rickettsia felis infection in Taiwan: A retrospective seroepidemiological survey of patients with suspected rickettsioses

Wan-Hsiu Yang, Meng-Shiuan Hsu, Pei-Yun Shu, Kun-Hsien Tsai, Chi-Tai Fang

PLOS Neglected Tropical Diseases: published April 19, 2021 | https://doi.org/10.1371/journal.pntd.0009355

Management of insecticides for use in disease vector control: Lessons from six countries in Asia and the Middle East

Henk van den Berg, Raman Velayudhan, Rajpal S. Yadav

PLOS Neglected Tropical Diseases: published April 30, 2021 | https://doi.org/10.1371/journal.pntd.0009358

Diagnostic accuracy of the WHO clinical definitions for dengue and implications for surveillance: A systematic review and meta-analysis

Nader Raafat, Shanghavie Loganathan, Mavuto Mukaka, Stuart D. Blacksell, Richard James Maude

PLOS Neglected Tropical Diseases: published April 26, 2021 | https://doi.org/10.1371/journal.pntd.0009359

Zika virus dysregulates the expression of astrocytic genes involved in neurodevelopment

Muhammad Adnan Shereen, Nadia Bashir, Rui Su, Fang Liu, Kailang Wu, Zhen Luo, Jianguo Wu

PLOS Neglected Tropical Diseases: published April 23, 2021 | https://doi.org/10.1371/journal.pntd.0009362

Identification of antigenic linear peptides in the soil-transmitted helminth and Schistosoma mansoni proteome

Johnny Vlaminck, Ole Lagatie, Daniel Dana, Zeleke Mekonnen, Peter Geldhof, Bruno Levecke, Lieven J. Stuyver

PLOS Neglected Tropical Diseases: published April 28, 2021 | https://doi.org/10.1371/journal.pntd.0009369

Serology for the diagnosis of human hepatic cystic echinococcosis and its relation with cyst staging: A systematic review of the literature with meta-analysis

Francesca Tamarozzi, Ronaldo Silva, Veronica Andrea Fittipaldo, Dora Buonfrate, Bruno Gottstein, Mar Siles-Lucas

PLOS Neglected Tropical Diseases: published April 28, 2021 | https://doi.org/10.1371/journal.pntd.0009370

Combined gene deletion of dihydrofolate reductase-thymidylate synthase and pteridine reductase in Leishmania infantum

Arijit Bhattacharya, Philippe Leprohon, Marc Ouellette

PLOS Neglected Tropical Diseases: published April 27, 2021 | https://doi.org/10.1371/journal.pntd.0009377

Prevalence of intestinal parasitic infection and its associated factors among primary school students in Ethiopia: A systematic review and meta-analysis

Moges Agazhe Assemie, Daniel Shitu Getahun, Yidersail Hune, Pammla Petrucka, Ayele Mamo Abebe, Animut Takele Telayneh, Mekdes Marew Ambaw, Daniel Bekele Ketema, Temesgen Getaneh, Belayneh Mengist, Muluneh Alene, Samuel Derbie Habtegiorgis

PLOS Neglected Tropical Diseases: published April 27, 2021 | https://doi.org/10.1371/journal.pntd.0009379

Metagenomic sequencing reveals viral abundance and diversity in mosquitoes from the Shaanxi-Gansu-Ningxia region, China

Xiaozhou He, Qikai Yin, Liwei Zhou, Lei Meng, Weijun Hu, Fan Li, Yang Li, Kun Han, Shaobai Zhang, Shihong Fu, Xiaoshu Zhang, Ji Wang, Songtao Xu, Yi Zhang, Ying He, Maoxing Dong, Xinxin Shen, Zheng Zhang, Kai Nie, Guodong Liang, Xuejun Ma, Huanyu Wang

PLOS Neglected Tropical Diseases: published April 26, 2021 | https://doi.org/10.1371/journal.pntd.0009381

"Kankasha" in Kassala: A prospective observational cohort study of the clinical characteristics, epidemiology, genetic origin, and chronic impact of the 2018 epidemic of Chikungunya virus infection in Kassala, Sudan

Hilary Bower, Mubarak el Karsany, Abd Alhadi Adam Hussein Adam, Mubarak Ibrahim Idriss, Ma’aaza Abasher Alzain, Mohamed Elamin Ahmed Alfakiyousif, Rehab Mohamed, Iman Mahmoud, Omer Albadri, Suha Abdulaziz Alnour Mahmoud, Orwa Ibrahim Abdalla, Mawahib Eldigail, Nuha Elagib, Ulrike Arnold, Bernardo Gutierrez, Oliver G. Pybus, Daniel P. Carter, Steven T. Pullan, Shevin T. Jacob, Tajeldin Mohammedein Abdallah, Benedict Gannon, Tom E. Fletcher

PLOS Neglected Tropical Diseases: published April 30, 2021 | https://doi.org/10.1371/journal.pntd.0009387

Plasma lipidome profiling of newborns with antenatal exposure to Zika virus

Nieli Rodrigues da Costa Faria, Adriano Britto Chaves-Filho, Luiz Carlos Junior Alcantara, Isadora Cristina de Siqueira, Juan Ignacio Calcagno, Sayuri Miyamoto, Ana Maria Bispo de Filippis, Marcos Yukio Yoshinaga

PLOS Neglected Tropical Diseases: published April 30, 2021 | https://doi.org/10.1371/journal.pntd.0009388

Adverse pregnancy outcomes are associated with Plasmodium vivax malaria in a prospective cohort of women from the Brazilian Amazon

Jamille Gregório Dombrowski, André Barateiro, Erika Paula Machado Peixoto, André Boler Cláudio da Silva Barros, Rodrigo Medeiros de Souza, Taane Gregory Clark, Susana Campino, Carsten Wrenger, Gerhard Wunderlich, Giuseppe Palmisano, Sabrina Epiphanio, Lígia Antunes Gonçalves, Claudio Romero Farias Marinho

PLOS Neglected Tropical Diseases: published April 29, 2021 | https://doi.org/10.1371/journal.pntd.0009390

Impact of deltamethrin-resistance in Aedes albopictus on its fitness cost and vector competence

Jielin Deng, Yijia Guo, Xinghua Su, Shuang Liu, Wenqiang Yang, Yang Wu, Kun Wu, Guiyun Yan, Xiao-Guang Chen

PLOS Neglected Tropical Diseases: published April 27, 2021 | https://doi.org/10.1371/journal.pntd.0009391

Zoonotic tuberculosis knowledge and practices among cattle handlers in selected districts of Bangladesh

Sk Shaheenur Islam, Tanzida Begum Rumi, S. M. Lutful Kabir, A. K. M. Anisur Rahman, Md. Mahmudul Hasan Faisal, Robiul Islam, Adri G. M. van der Zanden, Michael P. Ward, Allen G. Ross, Zeaur Rahim

PLOS Neglected Tropical Diseases: published April 30, 2021 | https://doi.org/10.1371/journal.pntd.0009394

Corrections

Correction: Helminth Colonization Is Associated with Increased Diversity of the Gut Microbiota

Soo Ching Lee, Mei San Tang, Yvonne A. L. Lim, Seow Huey Choy, Zachary D. Kurtz, Laura M. Cox, Uma Mahesh Gundra, Ilseung Cho, Richard Bonneau, Martin J. Blaser, Kek Heng Chua, P’ng Loke

PLOS Neglected Tropical Diseases: published April 7, 2021 | https://doi.org/10.1371/journal.pntd.0009325

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  1. Helminth Colonization Is Associated with Increased Diversity of the Gut Microbiota

Correction: CXCR3 chemokine receptor contributes to specific CD8+ T cell activation by pDC during infection with intracellular pathogens

Camila Pontes Ferreira, Leonardo Moro Cariste, Isaú Henrique Noronha, Danielle Fernandes Durso, Joseli Lannes-Vieira, Karina Ramalho Bortoluci, Daniel Araki Ribeiro, Douglas Golenbock, Ricardo Tostes Gazzinelli, José Ronnie Carvalho de Vasconcelos

PLOS Neglected Tropical Diseases: published April 7, 2021 | https://doi.org/10.1371/journal.pntd.0009326

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  1. CXCR3 chemokine receptor contributes to specific CD8+ T cell activation by pDC during infection with intracellular pathogens

Correction: Role of microglia in the dissemination of Zika virus from mother to fetal brain

Pei Xu, Chao Shan, Tiffany J. Dunn, Xuping Xie, Hongjie Xia, Junling Gao, Javier Allende Labastida, Zou Jing, Paula P. Villarreal, Caitlin R. Schlagal, Yongjia Yu, Gracie Vargas, Shannan L. Rossi, Nikos Vasilakis, Pei-Yong Shi, Scott C. Weaver, Ping Wu

PLOS Neglected Tropical Diseases: published April 13, 2021 | https://doi.org/10.1371/journal.pntd.0009344

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  1. Role of microglia in the dissemination of Zika virus from mother to fetal brain

Correction: Anopheles sundaicus complex and the presence of Anopheles epiroticus in Indonesia

Din Syafruddin, Yulia E. Lestari, Dendi H. Permana, Puji B. S. Asih, Brandyce St. Laurent, Siti Zubaidah, Ismail E. Rozi, Sully Kosasih, Shinta, Supratman Sukowati †, Lukman Hakim, Edhi Haryanto, Wibowo Mangunwardoyo, Michael J. Bangs, Neil F. Lobo

PLOS Neglected Tropical Diseases: published April 13, 2021 | https://doi.org/10.1371/journal.pntd.0009345

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Correction: A next generation vaccine against human rabies based on a single dose of a chimpanzee adenovirus vector serotype C

Federico Napolitano, Rossella Merone, Adele Abbate, Virginia Ammendola, Emma Horncastle, Francesca Lanzaro, Marialuisa Esposito, Alessandra Maria Contino, Roberta Sbrocchi, Andrea Sommella, Joshua D. Duncan, Joseph Hinds, Richard A. Urbanowicz, Armin Lahm, Stefano Colloca, Antonella Folgori, Jonathan K. Ball, Alfredo Nicosia, Benjamin Wizel, Stefania Capone, Alessandra Vitelli

PLOS Neglected Tropical Diseases: published April 13, 2021 | https://doi.org/10.1371/journal.pntd.0009348

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  1. A next generation vaccine against human rabies based on a single dose of a chimpanzee adenovirus vector serotype C

Correction: Epidemiology and Clinical Features of Patients with Visceral Leishmaniasis Treated by an MSF Clinic in Bakool Region, Somalia, 2004–2006

Marie-Eve Raguenaud, Anna Jansson, Veerle Vanlerberghe, Gert Van der Auwera, Stijn Deborggraeve, Jean-Claude Dujardin, Ioannis Orfanos, Tony Reid, Marleen Boelaert

PLOS Neglected Tropical Diseases: published April 19, 2021 | https://doi.org/10.1371/journal.pntd.0009356

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