Surgery is used to corrected in-turned eyelashes resulting from chronic chlamydia trachomatous infection. However, sometimes part or all of the eyelid turns in again following surgery. This eyelid has focal post-operative trichiasis affecting a small portion of the eyelid but still capable of causing paint and corneal damage. Gower et al. (2019)
Image Credit: MTSS Data Collection Team
Viewpoints
Access to prompt diagnosis: The missing link in preventing mental health disorders associated with neglected tropical diseases
Albert Picado, Sarah Nogaro, Israel Cruz, Sylvain Biéler, Laura Ruckstuhl, Jon Bastow, Joseph Mathu Ndung’u
PLOS Neglected Tropical Diseases: published October 17, 2019 | https://doi.org/10.1371/journal.pntd.0007679
Congenital Chagas disease: Updated recommendations for prevention, diagnosis, treatment, and follow-up of newborns and siblings, girls, women of childbearing age, and pregnant women
Yves Carlier, Jaime Altcheh, Andrea Angheben, Hector Freilij, Alejandro O. Luquetti, Alejandro G. Schijman, Manuel Segovia, Noemie Wagner, Pedro Albajar Vinas
PLOS Neglected Tropical Diseases: published October 24, 2019 | https://doi.org/10.1371/journal.pntd.0007694
Three drugs are unnecessary for treating paucibacillary leprosy—A critique of the WHO guidelines
Diana N. J. Lockwood, Saba Lambert, Aparna Srikantam, Joydeepa Darlong, V. V. Pai, C. Ruth Butlin, Barbara de Barros, Edessa Negera, Stephen L. Walker
PLOS Neglected Tropical Diseases: published October 31, 2019 | https://doi.org/10.1371/journal.pntd.0007671
Review
Management of insecticide resistance in the major Aedes vectors of arboviruses: Advances and challenges
Isabelle Dusfour, John Vontas, Jean-Philippe David, David Weetman, Dina M. Fonseca, Vincent Corbel, Kamaraju Raghavendra, Mamadou B. Coulibaly, Ademir J. Martins, Shinji Kasai, Fabrice Chandre
PLOS Neglected Tropical Diseases: published October 10, 2019 | https://doi.org/10.1371/journal.pntd.0007615
Research Articles
Develop and Field Evolution of Single Tube Nested PCR, SYBRGreen PCR Methods, for the Diagnosis of Leprosy in Paraffin-embedded Formalin Fixed Tissues in Yunnan Province, a Hyper endemic Area of Leprosy in China
Xiaohua Chen, Yan Xing, Jun He, Fuyue Tan, Yuangang You, Yan Wen
PLOS Neglected Tropical Diseases: published October 2, 2019 | https://doi.org/10.1371/journal.pntd.0007731
Portable infrared imaging for longitudinal limb volume monitoring in patients with lymphatic filariasis
Celia Zhou, Channa Yahathugoda, Lalindi De Silva, Upeksha Rathnapala, Grant Owen, Mirani Weerasooriya, Ramakrishna U. Rao, Gary J. Weil, Philip J. Budge
PLOS Neglected Tropical Diseases: published October 4, 2019 | https://doi.org/10.1371/journal.pntd.0007762
Endemic Disease Control Agents’ perception on the fight against Aedes aegypti and the prevention of arbovirus infections in Brazil
Cíntia Pereira Donateli, Ariadne Barbosa do Nascimento Einloft, André Luiz Coutinho Junior, Rosângela Minardi Mitre Cotta, Glauce Dias da Costa
PLOS Neglected Tropical Diseases: published October 4, 2019 | https://doi.org/10.1371/journal.pntd.0007741
A systematic review and evaluation of Zika virus forecasting and prediction research during a public health emergency of international concern
Pei-Ying Kobres, Jean-Paul Chretien, Michael A. Johansson, Jeffrey J. Morgan, Pai-Yei Whung, Harshini Mukundan, Sara Y. Del Valle, Brett M. Forshey, Talia M. Quandelacy, Matthew Biggerstaff, Cecile Viboud, Simon Pollett
PLOS Neglected Tropical Diseases: published October 4, 2019 | https://doi.org/10.1371/journal.pntd.0007451
A peridomestic Aedes malayensis population in Singapore can transmit yellow fever virus
Elliott F. Miot, Fabien Aubry, Stéphanie Dabo, Ian H. Mendenhall, Sébastien Marcombe, Cheong H. Tan, Lee C. Ng, Anna-Bella Failloux, Julien Pompon, Paul T. Brey, Louis Lambrechts
PLOS Neglected Tropical Diseases: published October 7, 2019 | https://doi.org/10.1371/journal.pntd.0007783
Feasibility of a point-of-care test based on quantum dots with a mobile phone reader for detection of antibody responses
Chan Lee, John Noh, Seth E. O’Neal, Armando E. Gonzalez, Hector H. Garcia, the Cysticercosis Working Group in Peru, Sukwan Handali
PLOS Neglected Tropical Diseases: published October 7, 2019 | https://doi.org/10.1371/journal.pntd.0007746
Pre-operative trichiatic eyelash pattern predicts post-operative trachomatous trichiasis
Emily W. Gower, Beatriz Munoz, Saul Rajak, Esmael Habtamu, Sheila K. West, Shannath L. Merbs, Jennifer C. Harding, Wondu Alemayehu, E. Kelly Callahan, Paul M. Emerson, Teshome Gebre, Matthew J. Burton
PLOS Neglected Tropical Diseases: published October 7, 2019 | https://doi.org/10.1371/journal.pntd.0007637
A hidden battle in the dirt: Soil amoebae interactions with Paracoccidioides spp
Patrícia Albuquerque, André Moraes Nicola, Diogo Almeida Gomes Magnabosco, Lorena da Silveira Derengowski, Luana Soares Crisóstomo, Luciano Costa Gomes Xavier, Stefânia de Oliveira Frazão, Fernanda Guilhelmelli, Marco Antônio de Oliveira, Jhones do Nascimento Dias, Fabián Andrés Hurtado, Marcus de Melo Teixeira, Allan Jefferson Guimarães, Hugo Costa Paes, Eduardo Bagagli, Maria Sueli Soares Felipe, Arturo Casadevall, Ildinete Silva-Pereira
PLOS Neglected Tropical Diseases: published October 7, 2019 | https://doi.org/10.1371/journal.pntd.0007742
Zika virus infection in pregnancy: Establishing a case definition for clinical research on pregnant women with rash in an active transmission setting
Ricardo Arraes de Alencar Ximenes, Demócrito de Barros Miranda-Filho, Elizabeth B. Brickley, Ulisses Ramos Montarroyos, Celina Maria Turchi Martelli, Thalia Velho Barreto de Araújo, Laura C. Rodrigues, Maria de Fatima Pessoa Militão de Albuquerque, Wayner Vieira de Souza, Priscila Mayrelle da Silva Castanha, Rafael F. O. França, Rafael Dhália, Ernesto T. A. Marques, on behalf of the Microcephaly Epidemic Research Group (MERG)
PLOS Neglected Tropical Diseases: published October 7, 2019 | https://doi.org/10.1371/journal.pntd.0007763
Longitudinal evaluation of asymptomatic Leishmania infection in HIV-infected individuals in North-West Ethiopia: A pilot study
Johan van Griensven, Saskia van Henten, Bewketu Mengesha, Mekibib Kassa, Emebet Adem, Mengistu Endris Seid, Saïd Abdellati, Wondimu Asefa, Tesfa Simegn, Degnachew Debasu, Tadfe Bogale, Yonas Gedamu, Dorien Van Den Bossche, Wim Adriaensen, Gert Van der Auwera, Lieselotte Cnops, Florian Vogt, Ermias Diro
PLOS Neglected Tropical Diseases: published October 8, 2019 | https://doi.org/10.1371/journal.pntd.0007765
Selecting behaviour change priorities for trachoma ‘F’ and ‘E’ interventions: A formative research study in Oromia, Ethiopia
Katie Greenland, Sian White, Katina Sommers, Adam Biran, Matthew J. Burton, Virginia Sarah, Wondu Alemayehu
PLOS Neglected Tropical Diseases: published October 9, 2019 | https://doi.org/10.1371/journal.pntd.0007784
Enduring extreme climate: Effects of severe drought on Triatoma brasiliensis populations in wild and man-made habitats of the Caatinga
Antonia C. Ribeiro, Otília Sarquis, Marli M. Lima, Fernando Abad-Franch
PLOS Neglected Tropical Diseases: published October 10, 2019 | https://doi.org/10.1371/journal.pntd.0007766
Identification of a systemic interferon-γ inducible antimicrobial gene signature in leprosy patients undergoing reversal reaction
Rosane M. B. Teles, Jing Lu, Maria Tió-Coma, Isabela M. B. Goulart, Sayera Banu, Deanna Hagge, Kidist Bobosha, Tom H. M. Ottenhoff, Matteo Pellegrini, Annemieke Geluk, Robert L. Modlin
PLOS Neglected Tropical Diseases: published October 10, 2019 | https://doi.org/10.1371/journal.pntd.0007764
Differential impact of mass and targeted praziquantel delivery on schistosomiasis control in school-aged children: A systematic review and meta-analysis
Danielle M. Cribb, Naomi E. Clarke, Suhail A. R. Doi, Susana Vaz Nery
PLOS Neglected Tropical Diseases: published October 11, 2019 | https://doi.org/10.1371/journal.pntd.0007808
Trends of leprosy and multibacillary infection in the state of Georgia since the early 1900s
Carter D. McCormick, Jacqueline Lea, Barbara M. Stryjewska, Ashton Thompson, Jessica K. Fairley
PLOS Neglected Tropical Diseases: published October 11, 2019 | https://doi.org/10.1371/journal.pntd.0007713
Molluscicidal activity and physiological toxicity of quaternary benzo[c]phenanthridine alkaloids (QBAs) from Macleaya cordata fruits on Oncomelania hupensis
Wenshan Ke, Chang Tu, Dezhi Cao, Xiong Lin, Qiqiang Sun, Qian Zhang
PLOS Neglected Tropical Diseases: published October 11, 2019 | https://doi.org/10.1371/journal.pntd.0007740
High burden and seasonal variation of paediatric scabies and pyoderma prevalence in The Gambia: A cross-sectional study
Edwin P. Armitage, Elina Senghore, Saffiatou Darboe, Momodou Barry, Janko Camara, Sulayman Bah, Michael Marks, Carla Cerami, Anna Roca, Martin Antonio, Claire E. Turner, Thushan I. de Silva
PLOS Neglected Tropical Diseases: published October 14, 2019 | https://doi.org/10.1371/journal.pntd.0007801
Acute Toxoplasma infection in pregnant women worldwide: A systematic review and meta-analysis
Ali Rostami, Seyed Mohammad Riahi, Despina G. Contopoulos-Ioannidis, H. Ray Gamble, Yadolah Fakhri, Malihe Nourollahpour Shiadeh, Masoud Foroutan, Hamed Behniafar, Ali Taghipour, Yvonne A. Maldonado, Ali H. Mokdad, Robin B. Gasser
PLOS Neglected Tropical Diseases: published October 14, 2019 | https://doi.org/10.1371/journal.pntd.0007807
Supporting evidence for a human reservoir of invasive non-Typhoidal Salmonella from household samples in Burkina Faso
Annelies S. Post, Seydou Nakanabo Diallo, Issa Guiraud, Palpouguini Lompo, Marc Christian Tahita, Jessica Maltha, Sandra Van Puyvelde, Wesley Mattheus, Benedikt Ley, Kamala Thriemer, Eli Rouamba, Karim Derra, Stijn Deborggraeve, Halidou Tinto, Jan Jacobs
PLOS Neglected Tropical Diseases: published October 14, 2019 | https://doi.org/10.1371/journal.pntd.0007782
Kaposi’s sarcoma-associated herpesvirus seropositivity is associated with parasite infections in Ugandan fishing communities on Lake Victoria islands
Angela Nalwoga, Emily L. Webb, Belinda Chihota, Wendell Miley, Bridgious Walusimbi, Jacent Nassuuna, Richard E. Sanya, Gyaviira Nkurunungi, Nazzarena Labo, Alison M. Elliott, Stephen Cose, Denise Whitby, Robert Newton
PLOS Neglected Tropical Diseases: published October 16, 2019 | https://doi.org/10.1371/journal.pntd.0007776
A systematic review of the epidemiology of human monkeypox outbreaks and implications for outbreak strategy
Ellen M. Beer, V. Bhargavi Rao
PLOS Neglected Tropical Diseases: published October 16, 2019 | https://doi.org/10.1371/journal.pntd.0007791
Analysis in a murine model points to IgG responses against the 34k2 salivary proteins from Aedes albopictus and Aedes aegypti as novel promising candidate markers of host exposure to Aedes mosquitoes
Sara Buezo Montero, Paolo Gabrieli, Francesco Severini, Leonardo Picci, Marco Di Luca, Federico Forneris, Luca Facchinelli, Marta Ponzi, Fabrizio Lombardo, Bruno Arcà
PLOS Neglected Tropical Diseases: published October 16, 2019 | https://doi.org/10.1371/journal.pntd.0007806
Human Chrysomya bezziana myiasis: A systematic review
Xianyi Zhou, Dzinkambani Moffat Kambalame, Sitong Zhou, Xiang Guo, Dan Xia, Yemei Yang, Rangke Wu, Juan Luo, Fenglong Jia, Mingchi Yuen, Yuehua Xu, Geyang Dai, Li Li, Tian Xie, Santhosh Puthiyakunnon, Wenxia Wei, Lixian Xie, Siting Liang, Yuqin Feng, Songgen Huang, Yongxuan Hu, Qianzhen Mo, Rongjia Mai, Xiaoqing Zhang, Philip Spradbery, Xiaohong Zhou
PLOS Neglected Tropical Diseases: published October 16, 2019 | https://doi.org/10.1371/journal.pntd.0007391
Positive association between Brucella spp. seroprevalences in livestock and humans from a cross-sectional study in Garissa and Tana River Counties, Kenya
Salome Kairu-Wanyoike, Doris Nyamwaya, Martin Wainaina, Johanna Lindahl, Enoch Ontiri, Salome Bukachi, Ian Njeru, Joan Karanja, Rosemary Sang, Delia Grace, Bernard Bett
PLOS Neglected Tropical Diseases: published October 17, 2019 | https://doi.org/10.1371/journal.pntd.0007506
Genetic and phenotypic characterization of recently discovered enterovirus D type 111
Serge Alain Sadeuh-Mba, Marie-Line Joffret, Arthur Mazitchi, Marie-Claire Endegue-Zanga, Richard Njouom, Francis Delpeyroux, Ionela Gouandjika-Vasilache, Maël Bessaud
PLOS Neglected Tropical Diseases: published October 17, 2019 | https://doi.org/10.1371/journal.pntd.0007797
Association of Phlebotomus guggisbergi with Leishmania major and Leishmania tropica in a complex transmission setting for cutaneous leishmaniasis in Gilgil, Nakuru county, Kenya
Barrack O. Owino, Damaris Matoke-Muhia, Yasser Alraey, Jackline Milkah Mwangi, Johnstone M. Ingonga, Philip M. Ngumbi, Aitor Casas-Sanchez, Alvaro Acosta-Serrano, Daniel K. Masiga
PLOS Neglected Tropical Diseases: published October 18, 2019 | https://doi.org/10.1371/journal.pntd.0007712
Dengue viral infection in Indonesia: Epidemiology, diagnostic challenges, and mutations from an observational cohort study
I Made Susila Utama, Nurhayati Lukman, Dewi Dian Sukmawati, Bachti Alisjahbana, Anggraini Alam, Dewi Murniati, I Made Gede Dwi Lingga Utama, Dwiyanti Puspitasari, Herman Kosasih, Ida Laksono, Muhammad Karyana, Mulya Rahma Karyanti, M. M. D. E. A. H. Hapsari, Ninny Meutia, C Jason Liang, Wahyu Nawang Wulan, Chuen-Yen Lau, Ketut Tuti Merati Parwati
PLOS Neglected Tropical Diseases: published October 21, 2019 | https://doi.org/10.1371/journal.pntd.0007785
Erythritol as a single carbon source improves cultural isolation of Burkholderia pseudomallei from rice paddy soils
Trung T. Trinh, Karoline Assig, Quyen T. L. Tran, André Goehler, Linh N. H. Bui, Claudia Wiede, Bettina Folli, Sabine Lichtenegger, Tinh T. Nguyen, Gabriel E. Wagner, Christian Kohler, Ivo Steinmetz
PLOS Neglected Tropical Diseases: published October 21, 2019 | https://doi.org/10.1371/journal.pntd.0007821
Cost-effectiveness and social outcomes of a community-based treatment for podoconiosis lymphoedema in the East Gojjam zone, Ethiopia
Natalia Hounsome, Meseret Molla Kassahun, Moses Ngari, James A. Berkley, Esther Kivaya, Patricia Njuguna, Greg Fegan, Abreham Tamiru, Abebe Kelemework, Tsige Amberbir, Annabelle Clarke, Trudie Lang, Melanie J. Newport, Andy McKay, Fikre Enquoselassie, Gail Davey
PLOS Neglected Tropical Diseases: published October 23, 2019 | https://doi.org/10.1371/journal.pntd.0007780
Evaluation of the geographical utility of Eastern Russell’s viper (Daboia siamensis) antivenom from Thailand and an assessment of its protective effects against venom-induced nephrotoxicity
Janeyuth Chaisakul, Jaffer Alsolaiss, Mongkon Charoenpitakchai, Kulachet Wiwatwarayos, Nattapon Sookprasert, Robert A. Harrison, Narongsak Chaiyabutr, Lawan Chanhome, Choo Hock Tan, Nicholas R. Casewell
PLOS Neglected Tropical Diseases: published October 23, 2019 | https://doi.org/10.1371/journal.pntd.0007338
Post kala azar dermal leishmaniasis and leprosy prevalence and distribution in the Muzaffarpur health and demographic surveillance site
Epco Hasker, Paritosh Malaviya, Vivek Kumar Scholar, Pieter de Koning, Om Prakash Singh, Sangeeta Kansal, Kristien Cloots, Marleen Boelaert, Shyam Sundar
PLOS Neglected Tropical Diseases: published October 25, 2019 | https://doi.org/10.1371/journal.pntd.0007798
Sand fly synthetic sex-aggregation pheromone co-located with insecticide reduces the incidence of infection in the canine reservoir of visceral leishmaniasis: A stratified cluster randomised trial
Orin Courtenay, Erin Dilger, Leo A. Calvo-Bado, Lidija Kravar-Garde, Vicky Carter, Melissa J. Bell, Graziella B. Alves, Raquel Goncalves, Muhammad M. Makhdoomi, Mikel A. González, Caris M. Nunes, Daniel P. Bray, Reginaldo P. Brazil, James G. C. Hamilton
PLOS Neglected Tropical Diseases: published October 25, 2019 | https://doi.org/10.1371/journal.pntd.0007767
Pgp3 seroprevalence and associations with active trachoma and ocular Chlamydia trachomatis infection in Malawi: cross-sectional surveys in six evaluation units
Sarah E. Burr, John Hart, Lyson Samikwa, David Chaima, Gretchen Cooley, Diana Martin, Michael Masika, Anthony W. Solomon, Robin L. Bailey, Khumbo Kalua
PLOS Neglected Tropical Diseases: published October 28, 2019 | https://doi.org/10.1371/journal.pntd.0007749
Co-developing climate services for public health: Stakeholder needs and perceptions for the prevention and control of Aedes-transmitted diseases in the Caribbean
Anna M. Stewart-Ibarra, Moory Romero, Avery Q. J. Hinds, Rachel Lowe, Roché Mahon, Cedric J. Van Meerbeeck, Leslie Rollock, Marquita Gittens-St. Hilaire, Sylvester St. Ville, Sadie J. Ryan, Adrian R. Trotman, Mercy J. Borbor-Cordova
PLOS Neglected Tropical Diseases: published October 28, 2019 | https://doi.org/10.1371/journal.pntd.0007772
Potential Use of Community-Based Rapid Diagnostic Tests for Febrile Illnesses: Formative Research in Peru and Cambodia
Valerie A. Paz-Soldan, Amy C. Morrison, Heng Sopheab, Julia Schwarz, Karin M. Bauer, Jennie L. Mckenney, Chhorvann Chhea, Vonthanak Saphonn, Dyna Khuon, Robert D. Hontz, Pamina M. Gorbach
PLOS Neglected Tropical Diseases: published October 28, 2019 | https://doi.org/10.1371/journal.pntd.0007773
Village-scale persistence and elimination of gambiense human African trypanosomiasis
Christopher N. Davis, Kat S. Rock, Erick Mwamba Miaka, Matt J. Keeling
PLOS Neglected Tropical Diseases: published October 28, 2019 | https://doi.org/10.1371/journal.pntd.0007838
Combined sterile insect technique and incompatible insect technique: The first proof-of-concept to suppress Aedes aegypti vector populations in semi-rural settings in Thailand
Pattamaporn Kittayapong, Suwannapa Ninphanomchai, Wanitch Limohpasmanee, Chitti Chansang, Uruyakorn Chansang, Piti Mongkalangoon
PLOS Neglected Tropical Diseases: published October 28, 2019 | https://doi.org/10.1371/journal.pntd.0007771
Comparison of four DNA extraction and three preservation protocols for the molecular detection and quantification of soil-transmitted helminths in stool
Mio Ayana, Piet Cools, Zeleke Mekonnen, Abdissa Biruksew, Daniel Dana, Nour Rashwan, Roger Prichard, Johnny Vlaminck, Jaco J. Verweij, Bruno Levecke
PLOS Neglected Tropical Diseases: published October 28, 2019 | https://doi.org/10.1371/journal.pntd.0007778
Buruli ulcer treatment: Rate of surgical intervention differs highly between treatment centers in West Africa
Anita C. Wadagni, Jonathan Steinhorst, Yves T. Barogui, P. M. Catraye, Ronald Gnimavo, Kabiru M. Abass, George Amofa, Michael Frimpong, Francisca N. Sarpong, Tjip S. van der Werf, Richard Phillips, Ghislain E. Sopoh, Christian R. Johnson, Ymkje Stienstra
PLOS Neglected Tropical Diseases: published October 28, 2019 | https://doi.org/10.1371/journal.pntd.0007866
Cryptosporidium spp., prevalence, molecular characterisation and socio-demographic risk factors among immigrants in Qatar
Sonia Boughattas, Jerzy M. Behnke, Duaa Al-Sadeq, Ahmed Ismail, Marawan Abu-Madi
PLOS Neglected Tropical Diseases: published October 29, 2019 | https://doi.org/10.1371/journal.pntd.0007750
A new human challenge model for testing heat-stable toxin-based vaccine candidates for enterotoxigenic Escherichia coli diarrhea – dose optimization, clinical outcomes, and CD4+ T cell responses
Sunniva Todnem Sakkestad, Hans Steinsland, Steinar Skrede, Kristine Lillebø, Dag Harald Skutlaberg, Anne Berit Guttormsen, Anton Zavialov, Sari Paavilainen, Hanne Søyland, Marianne Sævik, Astrid Rykkje Heien, Marit Gjerde Tellevik, Eileen Barry, Nina Langeland, Halvor Sommerfelt, Kurt Hanevik
PLOS Neglected Tropical Diseases: published October 30, 2019 | https://doi.org/10.1371/journal.pntd.0007823
Filovirus-reactive antibodies in humans and bats in Northeast India imply zoonotic spillover
Pilot Dovih, Eric D. Laing, Yihui Chen, Dolyce H. W. Low, B. R. Ansil, Xinglou Yang, Zhengli Shi, Christopher C. Broder, Gavin J. D. Smith, Martin Linster, Uma Ramakrishnan, Ian H. Mendenhall
PLOS Neglected Tropical Diseases: published October 31, 2019 | https://doi.org/10.1371/journal.pntd.0007733
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