Daily cleaning of personnel boots and gloves at the Ebola treatment center in Gueckedou, Guinea. See Bausch and Schwarz.
Image Credit: Frederique Jacquerioz
Editorial
Outbreak of Ebola Virus Disease in Guinea: Where Ecology Meets Economy
Daniel G. Bausch, Lara Schwarz
PLOS Neglected Tropical Diseases: published July 31, 2014 | https://doi.org/10.1371/journal.pntd.0003056
Viewpoints
Finding New Collaboration Models for Enabling Neglected Tropical Disease Drug Discovery
Michael P. Pollastri
PLOS Neglected Tropical Diseases: published July 3, 2014 | https://doi.org/10.1371/journal.pntd.0002866
Blood Drain: Soil-Transmitted Helminths and Anemia in Pregnant Women
Theresa W. Gyorkos, Nicolas L. Gilbert
PLOS Neglected Tropical Diseases: published July 10, 2014 | https://doi.org/10.1371/journal.pntd.0002912
Visceral Leishmaniasis as an AIDS Defining Condition: Towards Consistency across WHO Guidelines
Johan van Griensven, Koert Ritmeijer, Lutgarde Lynen, Ermias Diro
PLOS Neglected Tropical Diseases: published July 17, 2014 | https://doi.org/10.1371/journal.pntd.0002916
Dengue and the World Football Cup: A Matter of Timing
Christovam Barcellos, Rachel Lowe
PLOS Neglected Tropical Diseases: published July 24, 2014 | https://doi.org/10.1371/journal.pntd.0003022
The Global Burden of Disease Study 2010: Interpretation and Implications for the Neglected Tropical Diseases
Peter J. Hotez, Miriam Alvarado, María-Gloria Basáñez, Ian Bolliger, Rupert Bourne, Michel Boussinesq, Simon J. Brooker, Ami Shah Brown, Geoffrey Buckle, Christine M. Budke, Hélène Carabin, Luc E. Coffeng, Eric M. Fèvre, Thomas Fürst, Yara A. Halasa, Rashmi Jasrasaria, Nicole E. Johns, Jennifer Keiser, Charles H. King, Rafael Lozano, Michele E. Murdoch, Simon O'Hanlon, Sébastien D. S. Pion, Rachel L. Pullan, Kapa D. Ramaiah, Thomas Roberts, Donald S. Shepard, Jennifer L. Smith, Wilma A. Stolk, Eduardo A. Undurraga, Jürg Utzinger, Mengru Wang, Christopher J. L. Murray, Mohsen Naghavi
PLOS Neglected Tropical Diseases: published July 24, 2014 | https://doi.org/10.1371/journal.pntd.0002865
Policy Platform
Introducing a Dengue Vaccine to Mexico: Development of a System for Evidence-Based Public Policy Recommendations
Miguel Betancourt-Cravioto, Pablo Kuri-Morales, Jesús Felipe González-Roldán, Roberto Tapia-Conyer, the Mexican Dengue Expert Group
PLOS Neglected Tropical Diseases: published July 31, 2014 | https://doi.org/10.1371/journal.pntd.0003009
Historical Profiles and Perspectives
The Butantan Institute: History and Future Perspectives
Marcelo De Franco, Jorge Kalil
PLOS Neglected Tropical Diseases: published July 3, 2014 | https://doi.org/10.1371/journal.pntd.0002862
The Death and Life of the Resurrection Drug
Charles Ebikeme
PLOS Neglected Tropical Diseases: published July 10, 2014 | https://doi.org/10.1371/journal.pntd.0002910
Haiti National Program for the Elimination of Lymphatic Filariasis—A Model of Success in the Face of Adversity
Roland Oscar, Jean Frantz Lemoine, Abdel Nasser Direny, Luccene Desir, Valery E. Madsen Beau de Rochars, Mathieu J. P. Poirier, Ann Varghese, Ijeoma Obidegwu, Patrick J. Lammie, Thomas G. Streit, Marie Denise Milord
PLOS Neglected Tropical Diseases: published July 17, 2014 | https://doi.org/10.1371/journal.pntd.0002915
Reviews
Merits and Pitfalls of Currently Used Diagnostic Tools in Mycetoma
Wendy W. J. van de Sande, Ahmed H. Fahal, Michael Goodfellow, El Sheikh Mahgoub, Oliverio Welsh, Ed E. Zijlstra
PLOS Neglected Tropical Diseases: published July 3, 2014 | https://doi.org/10.1371/journal.pntd.0002918
Immune Regulation during Chronic Visceral Leishmaniasis
Rebecca J. Faleiro, Rajiv Kumar, Louise M. Hafner, Christian R. Engwerda
PLOS Neglected Tropical Diseases: published July 10, 2014 | https://doi.org/10.1371/journal.pntd.0002914
Oroya Fever and Verruga Peruana: Bartonelloses Unique to South America
Michael F. Minnick, Burt E. Anderson, Amorce Lima, James M. Battisti, Phillip G. Lawyer, Richard J. Birtles
PLOS Neglected Tropical Diseases: published July 17, 2014 | https://doi.org/10.1371/journal.pntd.0002919
Brucellosis as an Emerging Threat in Developing Economies: Lessons from Nigeria
Marie J. Ducrotoy, Wilson J. Bertu, Reuben A. Ocholi, Amahyel M. Gusi, Ward Bryssinckx, Sue Welburn, Ignacio Moriyón
PLOS Neglected Tropical Diseases: published July 24, 2014 | https://doi.org/10.1371/journal.pntd.0003008
Acute Chagas Disease: New Global Challenges for an Old Neglected Disease
Daniela V. Andrade, Kenneth J. Gollob, Walderez O. Dutra
PLOS Neglected Tropical Diseases: published July 31, 2014 | https://doi.org/10.1371/journal.pntd.0003010
Research Articles
Feasibility of a Lateral Flow Test for Neurocysticercosis Using Novel Up-Converting Nanomaterials and a Lightweight Strip Analyzer
Paul L. A. M. Corstjens, Claudia J. de Dood, Jeffrey W. Priest, Hans J. Tanke, Sukwan Handali, and the Cysticercosis Working Group in Peru
PLOS Neglected Tropical Diseases: published July 3, 2014 | https://doi.org/10.1371/journal.pntd.0002944
Feasible Introgression of an Anti-pathogen Transgene into an Urban Mosquito Population without Using Gene-Drive
Kenichi W. Okamoto, Michael A. Robert, Fred Gould, Alun L. Lloyd
PLOS Neglected Tropical Diseases: published July 3, 2014 | https://doi.org/10.1371/journal.pntd.0002827
Filarial Excretory-Secretory Products Induce Human Monocytes to Produce Lymphangiogenic Mediators
Tiffany Weinkopff, Charles Mackenzie, Rob Eversole, Patrick J. Lammie
PLOS Neglected Tropical Diseases: published July 10, 2014 | https://doi.org/10.1371/journal.pntd.0002893
Good Quality of Life in Former Buruli Ulcer Patients with Small Lesions: Long-Term Follow-up of the BURULICO Trial
Sandor Klis, Adelita Ranchor, Richard O. Phillips, Kabiru M. Abass, Wilson Tuah, Susanne Loth, Kristien Velding, Tjip S. van der Werf, Ymkje Stienstra
PLOS Neglected Tropical Diseases: published July 10, 2014 | https://doi.org/10.1371/journal.pntd.0002964
Wolbachia Enhances West Nile Virus (WNV) Infection in the Mosquito Culex tarsalis
Brittany L. Dodson, Grant L. Hughes, Oluwatobi Paul, Amy C. Matacchiero, Laura D. Kramer, Jason L. Rasgon
PLOS Neglected Tropical Diseases: published July 10, 2014 | https://doi.org/10.1371/journal.pntd.0002965
A Hematogenously Disseminated Orientia tsutsugamsushi-Infected Murine Model of Scrub Typhus
Thomas R. Shelite, Tais B. Saito, Nicole L. Mendell, Bin Gong, Guang Xu, Lynn Soong, Gustavo Valbuena, Donald H. Bouyer, David H. Walker
PLOS Neglected Tropical Diseases: published July 10, 2014 | https://doi.org/10.1371/journal.pntd.0002966
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Maurice Demanou, Régis Pouillot, Marc Grandadam, Pascal Boisier, Basile Kamgang, Jean Pierre Hervé, Christophe Rogier, Dominique Rousset, Christophe Paupy
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Experimental Infection of the Pig with Mycobacterium ulcerans: A Novel Model for Studying the Pathogenesis of Buruli Ulcer Disease
Miriam Bolz, Nicolas Ruggli, Marie-Thérèse Ruf, Meret E. Ricklin, Gert Zimmer, Gerd Pluschke
PLOS Neglected Tropical Diseases: published July 10, 2014 | https://doi.org/10.1371/journal.pntd.0002968
Predictive Tools for Severe Dengue Conforming to World Health Organization 2009 Criteria
Luis R. Carrasco, Yee Sin Leo, Alex R. Cook, Vernon J. Lee, Tun L. Thein, Chi Jong Go, David C. Lye
PLOS Neglected Tropical Diseases: published July 10, 2014 | https://doi.org/10.1371/journal.pntd.0002972
Acute Chagas Disease Induces Cerebral Microvasculopathy in Mice
Lindice Mitie Nisimura, Vanessa Estato, Elen Mello de Souza, Patricia A. Reis, Marcos Adriano Lessa, Hugo Caire Castro-Faria-Neto, Mirian Claudia de Souza Pereira, Eduardo Tibiriçá, Luciana Ribeiro Garzoni
PLOS Neglected Tropical Diseases: published July 10, 2014 | https://doi.org/10.1371/journal.pntd.0002998
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Libo Su, Yujuan Qi, Mei Zhang, Meiqian Weng, Xichen Zhang, Chienwen Su, Hai Ning Shi
PLOS Neglected Tropical Diseases: published July 10, 2014 | https://doi.org/10.1371/journal.pntd.0002987
Detection of Circulating Parasite-Derived MicroRNAs in Filarial Infections
Lucienne Tritten, Erica Burkman, Andrew Moorhead, Mohammed Satti, James Geary, Charles Mackenzie, Timothy Geary
PLOS Neglected Tropical Diseases: published July 17, 2014 | https://doi.org/10.1371/journal.pntd.0002971
Effect of Deworming on Physical Fitness of School-Aged Children in Yunnan, China: A Double-Blind, Randomized, Placebo-Controlled Trial
Peiling Yap, Fang-Wei Wu, Zun-Wei Du, Jan Hattendorf, Ran Chen, Jin-Yong Jiang, Susi Kriemler, Stefanie J. Krauth, Xiao-Nong Zhou, Jürg Utzinger, Peter Steinmann
PLOS Neglected Tropical Diseases: published July 10, 2014 | https://doi.org/10.1371/journal.pntd.0002983
Eosinophil Granule Proteins ECP and EPX as Markers for a Potential Early-Stage Inflammatory Lesion in Female Genital Schistosomiasis (FGS)
Charles Emile Ramarokoto, Anna Overgaard Kildemoes, Bodo Sahondra Randrianasolo, Pascaline Ravoniarimbinina, Vololomboahangy Elisabeth Ravaoalimalala, Peter Leutscher, Eyrun Floerecke Kjetland, Birgitte Jyding Vennervald
PLOS Neglected Tropical Diseases: published July 17, 2014 | https://doi.org/10.1371/journal.pntd.0002974
Identification of sVSG117 as an Immunodiagnostic Antigen and Evaluation of a Dual-Antigen Lateral Flow Test for the Diagnosis of Human African Trypanosomiasis
Lauren Sullivan, Jennifer Fleming, Lalitha Sastry, Angela Mehlert, Steven J. Wall, Michael A. J. Ferguson
PLOS Neglected Tropical Diseases: published July 17, 2014 | https://doi.org/10.1371/journal.pntd.0002976
Changing Patterns of Human Anthrax in Azerbaijan during the Post-Soviet and Preemptive Livestock Vaccination Eras
Ian Kracalik, Rakif Abdullayev, Kliment Asadov, Rita Ismayilova, Mehriban Baghirova, Narmin Ustun, Mazahir Shikhiyev, Aydin Talibzade, Jason K. Blackburn
PLOS Neglected Tropical Diseases: published July 17, 2014 | https://doi.org/10.1371/journal.pntd.0002985
Praziquantel, Mefloquine-Praziquantel, and Mefloquine-Artesunate-Praziquantel against Schistosoma haematobium: A Randomized, Exploratory, Open-Label Trial
Jennifer Keiser, Kigbafori D. Silué, Lukas K. Adiossan, Nicaise A. N'Guessan, N'Chou Monsan, Jürg Utzinger, Eliézer K. N'Goran
PLOS Neglected Tropical Diseases: published July 17, 2014 | https://doi.org/10.1371/journal.pntd.0002975
Serology of Paracoccidioidomycosis Due to Paracoccidioides lutzii
Gregory Gegembauer, Leticia Mendes Araujo, Edy Firmina Pereira, Anderson Messias Rodrigues, Anamaria Mello Miranda Paniago, Rosane Christine Hahn, Zoilo Pires de Camargo
PLOS Neglected Tropical Diseases: published July 17, 2014 | https://doi.org/10.1371/journal.pntd.0002986
Antimony Resistant Leishmania donovani but Not Sensitive Ones Drives Greater Frequency of Potent T-Regulatory Cells upon Interaction with Human PBMCs: Role of IL-10 and TGF-β in Early Immune Response
Rajan Guha, Shantanabha Das, June Ghosh, Shyam Sundar, Jean Claude Dujardin, Syamal Roy
PLOS Neglected Tropical Diseases: published July 17, 2014 | https://doi.org/10.1371/journal.pntd.0002995
Synergy Testing of FDA-Approved Drugs Identifies Potent Drug Combinations against Trypanosoma cruzi
Joseph D. Planer, Matthew A. Hulverson, Jennifer A. Arif, Ranae M. Ranade, Robert Don, Frederick S. Buckner
PLOS Neglected Tropical Diseases: published July 17, 2014 | https://doi.org/10.1371/journal.pntd.0002977
Neurocognitive Outcome of Children Exposed to Perinatal Mother-to-Child Chikungunya Virus Infection: The CHIMERE Cohort Study on Reunion Island
Patrick Gérardin, Sylvain Sampériz, Duksha Ramful, Brahim Boumahni, Marc Bintner, Jean-Luc Alessandri, Magali Carbonnier, Isabelle Tiran-Rajaoefera, Gilles Beullier, Irénée Boya, Tahir Noormahomed, Jocelyn Okoï, Olivier Rollot, Liliane Cotte, Marie-Christine Jaffar-Bandjee, Alain Michault, François Favier, Monique Kaminski, Alain Fourmaintraux, Xavier Fritel
PLOS Neglected Tropical Diseases: published July 17, 2014 | https://doi.org/10.1371/journal.pntd.0002996
Shift in Phenotypic Characteristics of Enterotoxigenic Escherichia coli (ETEC) Isolated from Diarrheal Patients in Bangladesh
Yasmin Ara Begum, Nabilah Ibnat Baby, Abu S. G. Faruque, Nusrat Jahan, Alejandro Cravioto, Ann-Mari Svennerholm, Firdausi Qadri
PLOS Neglected Tropical Diseases: published July 17, 2014 | https://doi.org/10.1371/journal.pntd.0003031
Long-Term and Seasonal Dynamics of Dengue in Iquitos, Peru
Steven T. Stoddard, Helen J. Wearing, Robert C. Reiner Jr, Amy C. Morrison, Helvio Astete, Stalin Vilcarromero, Carlos Alvarez, Cesar Ramal-Asayag, Moises Sihuincha, Claudio Rocha, Eric S. Halsey, Thomas W. Scott, Tadeusz J. Kochel, Brett M. Forshey
PLOS Neglected Tropical Diseases: published July 17, 2014 | https://doi.org/10.1371/journal.pntd.0003003
Leishmania amazonensis Amastigotes Highly Express a Tryparedoxin Peroxidase Isoform That Increases Parasite Resistance to Macrophage Antimicrobial Defenses and Fosters Parasite Virulence
Calvin A. Henard, Eric D. Carlsen, Christie Hay, Peter E. Kima, Lynn Soong
PLOS Neglected Tropical Diseases: published July 17, 2014 | https://doi.org/10.1371/journal.pntd.0003000
Transcriptome Sequencing and Developmental Regulation of Gene Expression in Anopheles aquasalis
André L. Costa-da-Silva, Osvaldo Marinotti, José M. C. Ribeiro, Maria C. P. Silva, Adriana R. Lopes, Michele S. Barros, Anderson Sá-Nunes, Bianca B. Kojin, Eneas Carvalho, Lincoln Suesdek, Mário Alberto C. Silva-Neto, Anthony A. James, Margareth L. Capurro
PLOS Neglected Tropical Diseases: published July 17, 2014 | https://doi.org/10.1371/journal.pntd.0003005
Recombinant Antigens Expressed in Pichia pastoris for the Diagnosis of Sleeping Sickness Caused by Trypanosoma brucei gambiense
Stijn Rogé, Liesbeth Van Nieuwenhove, Magali Meul, Annick Heykers, Annette Brouwer de Koning, Nicolas Bebronne, Yves Guisez, Philippe Büscher
PLOS Neglected Tropical Diseases: published July 17, 2014 | https://doi.org/10.1371/journal.pntd.0003006
In Vitro and In Vivo Miltefosine Susceptibility of a Leishmania amazonensis Isolate from a Patient with Diffuse Cutaneous Leishmaniasis
Adriano C. Coelho, Cristiana T. Trinconi, Carlos H. N. Costa, Silvia R. B. Uliana
PLOS Neglected Tropical Diseases: published July 17, 2014 | https://doi.org/10.1371/journal.pntd.0002999
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Rajiv Sarkar, Jacqueline E. Tate, Sitara S. R. Ajjampur, Deepthi Kattula, Jacob John, Honorine D. Ward, Gagandeep Kang
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The Population Structure of Vibrio cholerae from the Chandigarh Region of Northern India
Moataz Abd El Ghany, Jagadish Chander, Ankur Mutreja, Mamoon Rashid, Grant A. Hill-Cawthorne, Shahjahan Ali, Raeece Naeem, Nicholas R. Thomson, Gordon Dougan, Arnab Pain
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Risk Factors for Adverse Prognosis and Death in American Visceral Leishmaniasis: A Meta-analysis
Vinícius Silva Belo, Claudio José Struchiner, David Soeiro Barbosa, Bruno Warlley Leandro Nascimento, Marco Aurélio Pereira Horta, Eduardo Sérgio da Silva, Guilherme Loureiro Werneck
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MALDI-TOF Mass Spectrometry Detection of Pathogens in Vectors: The Borrelia crocidurae/Ornithodoros sonrai Paradigm
Aurélien Fotso Fotso, Oleg Mediannikov, Georges Diatta, Lionel Almeras, Christophe Flaudrops, Philippe Parola, Michel Drancourt
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Auranofin Is Highly Efficacious against Toxoplasma gondii In Vitro and in an In Vivo Experimental Model of Acute Toxoplasmosis
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Bat Rabies in Guatemala
James A. Ellison, Amy T. Gilbert, Sergio Recuenco, David Moran, Danilo A. Alvarez, Natalia Kuzmina, Daniel L. Garcia, Leonard F. Peruski, Mary T. Mendonça, Kim A. Lindblade, Charles E. Rupprecht
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PLOS Neglected Tropical Diseases: published July 31, 2014 | https://doi.org/10.1371/journal.pntd.0003058
Characterization of Enteroviruses from Non-Human Primates in Cameroon Revealed Virus Types Widespread in Humans along with Candidate New Types and Species
Serge Alain Sadeuh-Mba, Maël Bessaud, Marie-Line Joffret, Marie-Claire Endegue Zanga, Jean Balanant, Eitel Mpoudi Ngole, Richard Njouom, Jean-Marc Reynes, Francis Delpeyroux, Dominique Rousset
PLOS Neglected Tropical Diseases: published July 31, 2014 | https://doi.org/10.1371/journal.pntd.0003052
Evidence for Circulation of the Rift Valley Fever Virus among Livestock in the Union of Comoros
Matthieu Roger, Marina Beral, Séverine Licciardi, Miradje Soulé, Abdourahime Faharoudine, Coralie Foray, Marie-Marie Olive, Marianne Maquart, Abdouroihamane Soulaimane, Ahmed Madi Kassim, Catherine Cêtre-Sossah, Eric Cardinale
PLOS Neglected Tropical Diseases: published July 31, 2014 | https://doi.org/10.1371/journal.pntd.0003045
Using Mobile Health (mHealth) and Geospatial Mapping Technology in a Mass Campaign for Reactive Oral Cholera Vaccination in Rural Haiti
Jessica E. Teng, Dana R. Thomson, Jonathan S. Lascher, Max Raymond, Louise C. Ivers
PLOS Neglected Tropical Diseases: published July 31, 2014 | https://doi.org/10.1371/journal.pntd.0003050
Predicted Impact of Mass Drug Administration on the Development of Protective Immunity against Schistosoma haematobium
Kate M. Mitchell, Francisca Mutapi, Takafira Mduluza, Nicholas Midzi, Nicholas J. Savill, Mark E. J. Woolhouse
PLOS Neglected Tropical Diseases: published July 31, 2014 | https://doi.org/10.1371/journal.pntd.0003059
Transcriptional Correlates of Disease Outcome in Anticoagulant-Treated Non-Human Primates Infected with Ebolavirus
Sara Garamszegi, Judy Y. Yen, Anna N. Honko, Joan B. Geisbert, Kathleen H. Rubins, Thomas W. Geisbert, Yu Xia, Lisa E. Hensley, John H. Connor
PLOS Neglected Tropical Diseases: published July 31, 2014 | https://doi.org/10.1371/journal.pntd.0003061
An Integrated Lab-on-Chip for Rapid Identification and Simultaneous Differentiation of Tropical Pathogens
Jeslin J. L. Tan, Monica Capozzoli, Mitsuharu Sato, Wanitda Watthanaworawit, Clare L. Ling, Marjorie Mauduit, Benoît Malleret, Anne-Charlotte Grüner, Rosemary Tan, François H. Nosten, Georges Snounou, Laurent Rénia, Lisa F. P. Ng
PLOS Neglected Tropical Diseases: published July 31, 2014 | https://doi.org/10.1371/journal.pntd.0003043
Corrections
Correction: Safety and Efficacy Assessment of Two New Leprosy Skin Test Antigens: Randomized Double Blind Clinical Study
The PLOS Neglected Tropical Diseases Staff
PLOS Neglected Tropical Diseases: published July 7, 2014 | https://doi.org/10.1371/journal.pntd.0003065
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Correction: Identification and Characterization of Seminal Fluid Proteins in the Asian Tiger Mosquito, Aedes albopictus
The PLOS Neglected Tropical Diseases Staff
PLOS Neglected Tropical Diseases: published July 9, 2014 | https://doi.org/10.1371/journal.pntd.0003073
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Correction: Regulation of Schistosoma mansoni Development and Reproduction by the Mitogen-Activated Protein Kinase Signaling Pathway
The PLOS Neglected Tropical Diseases Staff
PLOS Neglected Tropical Diseases: published July 14, 2014 | https://doi.org/10.1371/journal.pntd.0003081