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PLoS Neglected Tropical Diseases Issue Image | Vol. 4(12) December 2010

Sleeping sickness patient rests in the ward, in Katanda HAT center (DR Congo).

A young man suffering from sleeping sickness rests on a bed at the Dipumba THA center in the province of Kasai, DRC, between two doses of intravenous treatment. He started NECT treatment (co-administration of intravenous eflornithine with oral nifurtimox) which was recently introduced for late-stage disease. Although NECT is a major improvement over the highly toxic melarsoprol, it still needs 2 daily intravenous infusions over 7 days. An oral treatment, as the one proposed with fexinidazole in this issue (see Torreele et al., 10.1371/journal.pntd.0000923), is urgently needed to support control programs and all efforts to eliminate sleeping sickness. DRC has the highest number of sleeping sickness cases in Africa.

Image Credit: Benoît Marquet

Citation: (2010) PLoS Neglected Tropical Diseases Issue Image | Vol. 4(12) December 2010. PLoS Negl Trop Dis 4(12): ev04.i12. https://doi.org/10.1371/image.pntd.v04.i12

Published: December 21, 2010

Copyright: © 2010 Torreele et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Sleeping sickness patient rests in the ward, in Katanda HAT center (DR Congo).

A young man suffering from sleeping sickness rests on a bed at the Dipumba THA center in the province of Kasai, DRC, between two doses of intravenous treatment. He started NECT treatment (co-administration of intravenous eflornithine with oral nifurtimox) which was recently introduced for late-stage disease. Although NECT is a major improvement over the highly toxic melarsoprol, it still needs 2 daily intravenous infusions over 7 days. An oral treatment, as the one proposed with fexinidazole in this issue (see Torreele et al., 10.1371/journal.pntd.0000923), is urgently needed to support control programs and all efforts to eliminate sleeping sickness. DRC has the highest number of sleeping sickness cases in Africa.

Image Credit: Benoît Marquet

https://doi.org/10.1371/image.pntd.v04.i12.g001

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