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Open Access
Peer-reviewed
Research Article
Anti-leishmanial activity of Brevinin 2R and its Lauric acid conjugate type against L. major: In vitro mechanism of actions and in vivo treatment potentials
Anti-leishmanial activity of Brevinin 2R and its Lauric acid conjugate type against L. major: In vitro mechanism of actions and in vivo treatment potentials
- Farnaz Zahedifard,
- Hyeryon Lee,
- Joo Hwan No,
- Mona Salimi,
- Negar Seyed,
- Ahmad Asoodeh,
- Sima Rafati
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- Published: February 27, 2019
- https://doi.org/10.1371/journal.pntd.0007217
About the Authors
- Farnaz Zahedifard
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Roles Data curation, Formal analysis, Investigation, Methodology, Software, Writing – original draft, Writing – review & editing
Affiliations Immunotherapy and Leishmania Vaccine Research Department, Pasteur Institute of Iran, Tehran, Iran, Leishmania Research Lab, Institut Pasteur Korea, Seongnam-si, Republic of Korea
- Hyeryon Lee
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Roles Investigation, Methodology, Software
Affiliation Leishmania Research Lab, Institut Pasteur Korea, Seongnam-si, Republic of Korea
- Joo Hwan No
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Roles Conceptualization, Funding acquisition, Resources, Supervision, Validation, Writing – review & editing
Affiliation Leishmania Research Lab, Institut Pasteur Korea, Seongnam-si, Republic of Korea
- Mona Salimi
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Roles Writing – review & editing
Affiliation Physiology and Pharmacology Department, Pasteur Institute of Iran, Tehran, Iran
- Negar Seyed
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Roles Methodology, Software, Validation
Affiliation Immunotherapy and Leishmania Vaccine Research Department, Pasteur Institute of Iran, Tehran, Iran
- Ahmad Asoodeh
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Roles Resources, Writing – review & editing
Affiliation Department of Chemistry, Faculty of Science, Ferdowsi University of Mashhad, Mashhad, Iran
- Sima Rafati
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Roles Conceptualization, Data curation, Funding acquisition, Project administration, Resources, Supervision, Validation, Visualization, Writing – review & editing
* E-mail: s_rafati@yahoo.com
Affiliation Immunotherapy and Leishmania Vaccine Research Department, Pasteur Institute of Iran, Tehran, Iran
Competing Interests
The authors have declared that no competing interests exist.