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Open Access

Peer-reviewed

Research Article

Failure of PCR to Detect Treponema pallidum ssp. pertenue DNA in Blood in Latent Yaws

  • Michael Marks ,

    Contributed equally to this work with: Michael Marks, Samantha Katz

    * E-mail: Michael.marks@lshtm.ac.uk

    Affiliations Clinical Research Department, Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, United Kingdom, The Hospital for Tropical Diseases, London, United Kingdom

  • Samantha Katz ,

    Contributed equally to this work with: Michael Marks, Samantha Katz

    Affiliation Laboratory Reference and Research Branch, Division of STD Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD and Tuberculosis Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America

  • Kai-Hua Chi,

    Affiliation Laboratory Reference and Research Branch, Division of STD Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD and Tuberculosis Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America

  • Ventis Vahi,

    Affiliation Ministry of Health and Medical Services, Honiara, Solomon Islands

  • Yongcheng Sun,

    Affiliation Laboratory Reference and Research Branch, Division of STD Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD and Tuberculosis Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America

  • David C. Mabey,

    Affiliations Clinical Research Department, Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, United Kingdom, The Hospital for Tropical Diseases, London, United Kingdom

  • Anthony W. Solomon,

    Affiliations Clinical Research Department, Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, United Kingdom, The Hospital for Tropical Diseases, London, United Kingdom

  • Cheng Y. Chen,

    Affiliation Laboratory Reference and Research Branch, Division of STD Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD and Tuberculosis Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America

  • Allan Pillay

    Affiliation Laboratory Reference and Research Branch, Division of STD Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD and Tuberculosis Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America

About the Authors

Michael Marks

Contributed equally to this work with: Michael Marks, Samantha Katz

* E-mail: Michael.marks@lshtm.ac.uk

Affiliations Clinical Research Department, Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, United Kingdom, The Hospital for Tropical Diseases, London, United Kingdom

Samantha Katz

Contributed equally to this work with: Michael Marks, Samantha Katz

Affiliation Laboratory Reference and Research Branch, Division of STD Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD and Tuberculosis Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America

Kai-Hua Chi

Affiliation Laboratory Reference and Research Branch, Division of STD Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD and Tuberculosis Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America

Ventis Vahi

Affiliation Ministry of Health and Medical Services, Honiara, Solomon Islands

Yongcheng Sun

Affiliation Laboratory Reference and Research Branch, Division of STD Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD and Tuberculosis Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America

David C. Mabey

Affiliations Clinical Research Department, Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, United Kingdom, The Hospital for Tropical Diseases, London, United Kingdom

Anthony W. Solomon

Affiliations Clinical Research Department, Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, United Kingdom, The Hospital for Tropical Diseases, London, United Kingdom

Cheng Y. Chen

Affiliation Laboratory Reference and Research Branch, Division of STD Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD and Tuberculosis Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America

Allan Pillay

Affiliation Laboratory Reference and Research Branch, Division of STD Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD and Tuberculosis Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: MM AWS DCM CYC AP. Performed the experiments: MM SK KHC VV YS AP. Analyzed the data: MM SK VV YS AWS DCM CYC AP. Contributed reagents/materials/analysis tools: MM CYC AP. Wrote the paper: MM SK KHC VV YS AWS DCM CYC AP.

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