Gut Microbiome is an exciting new field of research. Most of the bacteria in the gut are found in the large intestine (colon) and, over the past 30 years or more, interest in the gut microbial population – the microbiota – and its environment has intensified. Numerous research studies have shown that, far from being passive inhabitants of the gastrointestinal (GI) tract, the habitual residents of the gut (commensal micro-organisms) interact with their host in a very intricate manner. They may:

• Modulate the effect of potentially harmful bacteria.
• Impact the host’s GI tract, digestion and metabolism.
• Strengthen immune system.
• They might even influence functions beyond the gut such as influence the eating psychology.
  

Environmental factors like Diet, Antibiotic Usage and Lifestyle behaviors influence the diversity and composition of microbiota (healthy microbiota profile).

These environmental factors may adversely alter gut ecosystem (dysbiosis) that is frequently associated with increased susceptibility to infections as well as to non-communicable diseases like obesity, mental health, behavior, metabolic syndromes (e.g., diabetes and cardiovascular diseases), allergy and other inflammatory diseases.

These observations imply that it may be possible to design new strategies for the management of diseases by manipulating gut microbiota. The common practice now available is the use of functional foods including prebiotics, dietary fiber and probiotics to rehabilitate gut ecosystem.

Functional foods including Probiotics and Prebiotics and their impact on gut health and immunity is a growing area worldwide. After deliberations with scientists from academia and industry ILSI India felt that it is important to move forward with cooperation and collaboration of leading public sector and private sector organizations and create a platform for sharing the knowledge. A formal structure will facilitate focused attention to this important area of work.

The Knowledge Center was launched in New Delhi on October 4. It is unique and will focus on collation and dissemination of information generated by research organizations worldwide and act as a bridge between research and practical applications.

• Provide a knowledge sharing platform by organizing seminars/ conferences/ workshops on recent advances in the science of human microbiome and functional foods including prebiotics, dietary fiber and probiotics.
• Undertake studies to help fill/ understand gaps in consumer/industry understanding of science of functional foods including probiotics.
• Share recent developments in research with all stakeholders.
• Look at challenges faced by this sector and encourage all stakeholders to adopt global best practices.
• Create a Think Tank, involving stakeholders from Government, Academia as well as Industry, that will work towards sharing relevant research and technological developments in the area of human microbiome and functional foods.