科学研究

1.Guo Minghui, Zhu Yuwei, Lin Zhiying and Huang Zhiwei#

Cryo-EM structure of the ssDNA-activated SPARTA complex

Cell Research


2.Yaning Duan, Nancy C. P. Leong, Jing Zhao and Long N. Nguyen #,Yuanzheng He #

Structural basis of Sphingosine-1-phosphate transport via human SPNS2

Cell Research


3.Yin Han and He Yuanzheng#

Structural basis of omega-3 fatty acid receptor FFAR4 activation and G protein coupling selectivity

Cell Research


4.Zhang Boya and Gu Ning#

Foodborne Carbon Dot Exposure Induces Insulin Resistance through Gut Microbiota Dysbiosis and Damaged Intestinal Mucus Layer

ACS Nano


5.Sun Xiaofeng and Chen Xi#

Small molecule-nanobody conjugate induced proximity controls intracellular processes and modulates endogenous unligandable targets

Nature Communications


6.Liang Jiale and He Yuanzheng#

Structural basis of lysophosphatidylserine receptor GPR174 ligand recognition and activation

Nature Communications


7.Wang Chao and Tian Weiming#

The KLF7/PFKL/ACADL axis modulates cardiac metabolic remodelling during cardiac hypertrophy in male mice

Nature Communications


8.Zhang Wenxin, Dai Junren and Hu Ying#

SMURF2 predisposes cancer cell toward ferroptosis in GPX4-independent manners by promoting GSTP1 degradation

Molecular Cell


9.Lin Qingyu and Hu Ying#

Long noncoding RNA HITT coordinates with RGS2 to inhibit PD-L1 translation in T cell immunity

Journal of clinical investigation


10.He Huiping and Chen Xi#

ATNC:Versatile Nanobody Chimeras for Autophagic Degradation of Intracellular Unligandable and Undruggable Proteins

Journal of the American Chemical Society


11.Sun Haoxiu, Liu Chao, Han Fang and Nie Huan#,Yanqiao Zhang # ,Li Yu#

The regulation loop of MARVELD1 interacting with PARP1 in DNA damage response maintains genome stability and promotes therapy resistance of cancer cells

Cell Death and Differentiation


12.Liu Ziteng and Gao Wenpeng#, Fu Yili#

Surface deformation tracking in monocular laparoscopic video

Medical Image Analysis


13.Lin Qingyu and Hu Ying#

The opportunities and challenges in immunotherapy: Insights from the regulation of PD-L1 in cancer cells

Cancer Letters


14.Si Kaixue and Li Minghui#

The structure of Plasmodium falciparum multidrug resistance protein 1 reveals an N-terminal regulatory domain

Proceedings of the National Academy of Sciences of the United States of America


15.Shi Yuying and Wang Guangfu#

Laminar and dorsoventral organization of layer 1 interneuronal microcircuitry in superficial layers of the medial entorhinal cortex

Cell Reports


16.Li Xinzhi, Yang Ying, and Chen Zheng#

Deficiency of WTAP in islet beta cells results in beta cell failure and diabetes in mice

Diabetologia


17.Zhang Kai and Cong Hua#, Yang Qian#

The role of pH transcription factor Appacc in upregulation of pullulan biosynthesis in Aureobasidium pullulans using potato waste as a substrate

International Journal of Biological Macromolecules


18.Li Xinzhi, Yang Ying, and Chen Zheng#

Downregulation of the m6A reader protein YTHDC1 leads to islet β-cell failure and diabetes

Metabolism


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