Mesenchymal stem cell based regenerative medicine technologies for treatment of radiation induced lesions
Project Type
Coordinated Research ProjectProject Code
CRP
Approved Date
30 June 2025Project Status
New - Collecting or Evaluating proposalsDescription
New title: Mesenchymal stem cell based regenerative medicine technologies for treatment of radiation induced lesions
Despite current treatments, patients continue to suffer from cutaneous radiation syndrome (CRS) necessitating exploration and implementation of new technologies. Regenerative medicine, by way of adult mesenchymal stem/stromal cell therapy (MSCT), provides novel solutions, which help to improve patients’ quality of life. The main aim of the project is to disseminate and improve adult MSCT, tissue engineering and biobanking technology for treatment of CRS, including experimental research, pre- and clinical studies, in purview of regulatory guidance.
Objectives
Develop adult mesenchymal stem/stromal cell therapy (MSCT), optionally in combination with artificial tissue engineering, to treat cutaneous radiation syndrome (CRS), including experimental research, pre- and clinical studies, in purview of tissue banking and regulatory guidance
Specific Objectives
Harmonise regulatory framework of MSCT for treatment of CRS
Deliver an integrated knowledge exchange pathway for research and methods of MSCT
Evaluate the efficacy of different MSCT protocols depending on radiation lesion characteristics and confounding factors
Integrate MSCT with tissue engineering and biobanking to promote the use of regenerative medicine for treatment of CRS
Produce recommendations that create regenerative medicine solutions to the challenges of existing and available methods of treatment of CRS
Establish MSCT network of institutions engaged in regenerative medicine for treatment of CRS
Disseminate knowledge and best practices of MSCT in regenerative medicine for treatment of CRS