Reactome Pathway Database

Schema > Reaction > Entries

DLD dimer dehydrogenates dihydrolipoyl Show undefined attributes

catalystActivity

[CatalystActivity:10534844] dihydrolipoyl dehydrogenase (NADH) activity of BCKDH [mitochondrial matrix]

category transition

compartment

[Compartment:5460] mitochondrial matrix

created [InstanceEdit:10424722] Weiser, Joel, 2025年08月27日

dbId 10534846

displayName DLD dimer dehydrogenates dihydrolipoyl

eventOf

[Pathway:R-SSC-9859138] BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV - Sus scrofa

evidenceType [EvidenceType:9965817] inferred by electronic annotation

followingEvent

[Reaction:R-SSC-9859148] BCKDHA:BCKDHB tetramer decarboxylates KIC, KMVA, KIV - Sus scrofa

inferredFrom

[Reaction:R-HSA-9859172] DLD dimer dehydrogenates dihydrolipoyl - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

DLD dimer dehydrogenates dihydrolipoyl

output

precedingEvent

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:49633] Sus scrofa

stId R-SSC-9859172

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-SSC-9859138] BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV

(inferredTo)

[Reaction:R-HSA-9859172] DLD dimer dehydrogenates dihydrolipoyl

(precedingEvent)

[Reaction:R-SSC-9859148] BCKDHA:BCKDHB tetramer decarboxylates KIC, KMVA, KIV

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