Reactome Pathway Database

Schema > Reaction > Entries

PPM1K dephosphorylates p-BCKDH Show undefined attributes

catalystActivity

[CatalystActivity:10503832] [3-methyl-2-oxobutanoate dehydrogenase (lipoamide)]-phosphatase activity of PPM1K:Mn2+ [mitochondrial matrix]

category transition

compartment

[Compartment:5460] mitochondrial matrix

created [InstanceEdit:10424722] Weiser, Joel, 2025年08月27日

dbId 10503834

displayName PPM1K dephosphorylates p-BCKDH

eventOf

[Pathway:R-SSC-70895] Branched-chain amino acid catabolism - Sus scrofa

evidenceType [EvidenceType:9965817] inferred by electronic annotation

followingEvent

goBiologicalProcess [GO_BiologicalProcess:24670] positive regulation of amino acid metabolic process

inferredFrom

[Reaction:R-HSA-5693153] PPM1K dephosphorylates p-BCKDH - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

PPM1K dephosphorylates p-BCKDH
H2O + O-phospho-L-seryl-(3-methyl-2-oxobutanoate dehydrogenase) => L-seryl-(3-methyl-2-oxobutanoate dehydrogenase) + phosphate

output

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:49633] Sus scrofa

stId R-SSC-5693153

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-SSC-70895] Branched-chain amino acid catabolism

(precedingEvent)

(inferredTo)

[Reaction:R-HSA-5693153] PPM1K dephosphorylates p-BCKDH

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