Reactome Pathway Database

Schema > Reaction > Entries

ADRA2A,B,C bind ADR,NAd Show undefined attributes

category binding

compartment

created [InstanceEdit:10424722] Weiser, Joel, 2025年08月27日

dbId 10453891

displayName ADRA2A,B,C bind ADR,NAd

eventOf

evidenceType [EvidenceType:9965817] inferred by electronic annotation

followingEvent

[Reaction:R-SSC-749446] Liganded Gz-activating GPCRs bind inactive heterotrimeric G-protein Gz - Sus scrofa

inferredFrom

[Reaction:R-HSA-390663] ADRA2A,B,C bind ADR,NAd - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

ADRA2A,B,C bind ADR,NAd
Alpha-2 adrenoceptors bind catecholamines

output

[Complex:R-SSC-390700] ADRA2A,B,C:ADR,NAd [plasma membrane]

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:49633] Sus scrofa

stId R-SSC-390663

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

(precedingEvent)

[Reaction:R-SSC-749446] Liganded Gz-activating GPCRs bind inactive heterotrimeric G-protein Gz

(inferredTo)

[Reaction:R-HSA-390663] ADRA2A,B,C bind ADR,NAd

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