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Schema
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Reaction
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Entries
ADRA2A,B,C bind ADR,NAd
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authored
[InstanceEdit:390626] Jassal, Bijay, 2009年02月10日
category
binding
compartment
[Compartment:984] extracellular region
[Compartment:876] plasma membrane
created
[InstanceEdit:390626] Jassal, Bijay, 2009年02月10日
dbId
390663
displayName
ADRA2A,B,C bind ADR,NAd
edited
[InstanceEdit:390626] Jassal, Bijay, 2009年02月10日
eventOf
[Pathway:R-HSA-392023] Adrenaline signalling through Alpha-2 adrenergic receptor - Homo sapiens
[Pathway:R-HSA-390696] Adrenoceptors - Homo sapiens
followingEvent
[Reaction:R-HSA-749446] Liganded Gz-activating GPCRs bind inactive heterotrimeric G-protein Gz - Homo sapiens
input
[DefinedSet:R-ALL-390627] ADR, NAd [extracellular region]
[DefinedSet:R-HSA-390664] ADRA2A,B,C [plasma membrane]
isInDisease
false
isInferred
false
literatureReference
[LiteratureReference:390787] Cloning, sequencing, and expression of the gene coding for the human platelet alpha 2-adrenergic receptor
[LiteratureReference:390804] Cloning, expression, and pharmacological characterization of a human alpha 2B-adrenergic receptor
[LiteratureReference:390683] Cloning, functional expression and tissue distribution of human cDNA for the alpha 1C-adrenergic receptor
maxDepth
1
modified
[InstanceEdit:10867632] Weiser, Joel, 2025年08月27日
name
ADRA2A,B,C bind ADR,NAd
Alpha-2 adrenoceptors bind catecholamines
orthologousEvent
[Reaction:R-CEL-390663] ADRA2A,B,C bind ADR,NAd - Caenorhabditis elegans
[Reaction:R-DME-390663] ADRA2A,B,C bind ADR,NAd - Drosophila melanogaster
[Reaction:R-GGA-390663] ADRA2A,B,C bind ADR,NAd - Gallus gallus
[Reaction:R-XTR-390663] ADRA2A,B,C bind ADR,NAd - Xenopus tropicalis
[Reaction:R-DRE-390663] ADRA2A,B,C bind ADR,NAd - Danio rerio
[Reaction:R-SSC-390663] ADRA2A,B,C bind ADR,NAd - Sus scrofa
[Reaction:R-BTA-390663] ADRA2A,B,C bind ADR,NAd - Bos taurus
[Reaction:R-CFA-390663] ADRA2A,B,C bind ADR,NAd - Canis familiaris
[Reaction:R-RNO-390663] ADRA2A,B,C bind ADR,NAd - Rattus norvegicus
[Reaction:R-MMU-390663] ADRA2A,B,C bind ADR,NAd - Mus musculus
output
[Complex:R-HSA-390700] ADRA2A,B,C:ADR,NAd [plasma membrane]
releaseDate
2009年04月01日
reviewStatus
[ReviewStatus:9821382] five stars
reviewed
[InstanceEdit:392262] D'Eustachio, P, 2009年03月02日 09:24:35
schemaClass
Reaction
species
[Species:48887] Homo sapiens
stId
R-HSA-390663
summation
[Summation:390801] Alpha-2 adrenoceptors couple with G protein alpha-i subtype ...
updateTrackers
[UpdateTracker:9777814] Update Tracker - [Reaction:390663] ADRA2A,B,C bind ADR,NAd - v69:[removeRegulator]
[UpdateTracker:9791552] Update Tracker - [Reaction:390663] ADRA2A,B,C bind ADR,NAd - v29:[modifyText]
[UpdateTracker:9778845] Update Tracker - [Reaction:390663] ADRA2A,B,C bind ADR,NAd - v67:[addRegulator]
Referrals
(updatedInstance)
[UpdateTracker:9777814] Update Tracker - [Reaction:390663] ADRA2A,B,C bind ADR,NAd - v69:[removeRegulator]
[UpdateTracker:9791552] Update Tracker - [Reaction:390663] ADRA2A,B,C bind ADR,NAd - v29:[modifyText]
[UpdateTracker:9778845] Update Tracker - [Reaction:390663] ADRA2A,B,C bind ADR,NAd - v67:[addRegulator]
(hasEvent)
[Pathway:R-HSA-392023] Adrenaline signalling through Alpha-2 adrenergic receptor
[Pathway:R-HSA-390696] Adrenoceptors
(precedingEvent)
[Reaction:R-HSA-749446] Liganded Gz-activating GPCRs bind inactive heterotrimeric G-protein Gz
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