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Schema > Reaction > Entries

MAOA:FAD oxidatively deaminates of 5HT Show undefined attributes

catalystActivity

[CatalystActivity:10434472] primary methylamine oxidase activity of MAOA:FAD [mitochondrial outer membrane]

category transition

compartment

created [InstanceEdit:10424722] Weiser, Joel, 2025年08月27日

dbId 10434474

displayName MAOA:FAD oxidatively deaminates of 5HT

eventOf

[Pathway:R-SSC-380612] Metabolism of serotonin - Sus scrofa
[Pathway:R-SSC-141333] Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB - Sus scrofa

evidenceType [EvidenceType:9965817] inferred by electronic annotation

inferredFrom

[Reaction:R-HSA-141186] MAOA:FAD oxidatively deaminates of 5HT - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

MAOA:FAD oxidatively deaminates of 5HT
H2O + O2 + serotonin => (5-hydroxyindol-3-yl)acetaldehyde + H2O2 + NH4(+)

output

precedingEvent

[Reaction:R-SSC-444008] SLC6A4 co-transports 5HT, Cl-, Na+ from extracellular region to cytosol - Sus scrofa

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:49633] Sus scrofa

stId R-SSC-141186

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

(inferredTo)

[Reaction:R-HSA-141186] MAOA:FAD oxidatively deaminates of 5HT

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