Reactome Pathway Database

Schema > Reaction > Entries

Cysteine is degraded to pyruvate and H2S Show undefined attributes

catalystActivity

[CatalystActivity:10016900] carbon-sulfur lyase activity of PXLP-K212-CTH tetramer [cytosol]

category transition

compartment

[Compartment:70101] cytosol

created [InstanceEdit:9965813] Weiser, Joel, 2025年08月27日

dbId 10016925

displayName Cysteine is degraded to pyruvate and H2S

eventOf

[Pathway:R-MMU-1614558] Degradation of cysteine and homocysteine - Mus musculus

evidenceType [EvidenceType:9965817] inferred by electronic annotation

inferredFrom

[Reaction:R-HSA-1614614] Cysteine is degraded to pyruvate and H2S - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

Cysteine is degraded to pyruvate and H2S
H2O + L-cysteine => H(+) + hydrogen sulfide + NH4(+) + pyruvate

output

precedingEvent

[Reaction:R-MMU-1614583] PXLP-K212-CTH cleaves L-Cystathionine - Mus musculus

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:48892] Mus musculus

stId R-MMU-1614614

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-MMU-1614558] Degradation of cysteine and homocysteine

(inferredTo)

[Reaction:R-HSA-1614614] Cysteine is degraded to pyruvate and H2S

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