Reactome Pathway Database
Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Reactome Pathway Database
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
Schema
>
Reaction
>
Entries
Cysteine is degraded to pyruvate and H2S
Show undefined attributes
Go to Details
authored
[InstanceEdit:1237120] Stephan, R, 2010年10月24日
catalystActivity
[CatalystActivity:1614529] carbon-sulfur lyase activity of PXLP-K212-CTH tetramer [cytosol]
category
transition
compartment
[Compartment:70101] cytosol
created
[InstanceEdit:1614621] Jassal, Bijay, 2011年09月29日
crossReference
[DatabaseIdentifier:9929700] RHEA:24932
dbId
1614614
displayName
Cysteine is degraded to pyruvate and H2S
edited
[InstanceEdit:1614621] Jassal, Bijay, 2011年09月29日
eventOf
[Pathway:R-HSA-1614558] Degradation of cysteine and homocysteine - Homo sapiens
followingEvent
[Reaction:R-HSA-1614665] SQR oxidizes sulfide to bound persulfide - Homo sapiens
input
[SimpleEntity:R-ALL-29356] H2O [cytosol]
[SimpleEntity:R-ALL-111707] L-Cys [cytosol]
isChimeric
false
isInDisease
false
isInferred
false
literatureReference
[LiteratureReference:1614602] H2S biogenesis by human cystathionine gamma-lyase leads to the novel sulfur metabolites lanthionine and homolanthionine and is responsive to the grade of hyperhomocysteinemia
[LiteratureReference:1625216] Kinetics and inhibition of recombinant human cystathionine gamma-lyase. Toward the rational control of transsulfuration
maxDepth
1
modified
[InstanceEdit:11033291] Weiser, Joel, 2025年08月28日
name
Cysteine is degraded to pyruvate and H2S
H2O + L-cysteine => H(+) + hydrogen sulfide + NH4(+) + pyruvate
orthologousEvent
[Reaction:R-SCE-1614614] Cysteine is degraded to pyruvate and H2S - Saccharomyces cerevisiae
[Reaction:R-SPO-1614614] Cysteine is degraded to pyruvate and H2S - Schizosaccharomyces pombe
[Reaction:R-DDI-1614614] Cysteine is degraded to pyruvate and H2S - Dictyostelium discoideum
[Reaction:R-CEL-1614614] Cysteine is degraded to pyruvate and H2S - Caenorhabditis elegans
[Reaction:R-DME-1614614] Cysteine is degraded to pyruvate and H2S - Drosophila melanogaster
[Reaction:R-GGA-1614614] Cysteine is degraded to pyruvate and H2S - Gallus gallus
[Reaction:R-XTR-1614614] Cysteine is degraded to pyruvate and H2S - Xenopus tropicalis
[Reaction:R-DRE-1614614] Cysteine is degraded to pyruvate and H2S - Danio rerio
[Reaction:R-SSC-1614614] Cysteine is degraded to pyruvate and H2S - Sus scrofa
[Reaction:R-BTA-1614614] Cysteine is degraded to pyruvate and H2S - Bos taurus
[Reaction:R-CFA-1614614] Cysteine is degraded to pyruvate and H2S - Canis familiaris
[Reaction:R-RNO-1614614] Cysteine is degraded to pyruvate and H2S - Rattus norvegicus
[Reaction:R-MMU-1614614] Cysteine is degraded to pyruvate and H2S - Mus musculus
output
[SimpleEntity:R-ALL-70106] H+ [cytosol]
[SimpleEntity:R-ALL-1614532] H2S [cytosol]
[SimpleEntity:R-ALL-31633] NH4+ [cytosol]
[SimpleEntity:R-ALL-29398] PYR [cytosol]
precedingEvent
[Reaction:R-HSA-1614583] PXLP-K212-CTH cleaves L-Cystathionine - Homo sapiens
previousReviewStatus
[ReviewStatus:9821385] four stars
releaseDate
2011年12月06日
reviewStatus
[ReviewStatus:9821382] five stars
reviewed
[InstanceEdit:1660489] D'Eustachio, P, 2011年10月13日
[InstanceEdit:9939375] Hill, David P, 2025年02月25日
schemaClass
Reaction
species
[Species:48887] Homo sapiens
stId
R-HSA-1614614
summation
[Summation:1614662] Alpha,beta-elimination activity of cystathionine-gamma-lyase...
updateTrackers
[UpdateTracker:9939672] Update Tracker - [Reaction:1614614] Cysteine is degraded to pyruvate and H2S - v92:[add_removeOutput, modifyText]
Referrals
(updatedInstance)
[UpdateTracker:9939672] Update Tracker - [Reaction:1614614] Cysteine is degraded to pyruvate and H2S - v92:[add_removeOutput, modifyText]
(hasEvent)
[Pathway:R-HSA-1614558] Degradation of cysteine and homocysteine
(precedingEvent)
[Reaction:R-HSA-1614665] SQR oxidizes sulfide to bound persulfide
© 2025
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text
Download
Close
AltStyle
によって変換されたページ
(->オリジナル)
/
アドレス:
モード:
デフォルト
音声ブラウザ
ルビ付き
配色反転
文字拡大
モバイル