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Schema
>
BlackBoxEvent
>
Entries
Unwinding of DNA for the nascent HIV-1 transcript
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authored
[InstanceEdit:165064] Matthews, L, Rice, AP, 2005年07月27日 00:00:00
catalystActivity
[CatalystActivity:109879] 3'-5' DNA helicase activity of TFIIH [nucleoplasm]
category
uncertain
compartment
[Compartment:7660] nucleoplasm
created
[InstanceEdit:9613488] Gillespie, Marc E, 2018年07月13日
crossReference
[DatabaseIdentifier:11944912] Mondo:0005109
dbId
9613498
disease
[Disease:1660559] Human immunodeficiency virus infectious disease
displayName
Unwinding of DNA for the nascent HIV-1 transcript
edited
[InstanceEdit:165066] Matthews, L, 2005年07月26日 23:29:22
eventOf
[Pathway:R-HSA-167162] RNA Polymerase II HIV Promoter Escape - Homo sapiens
followingEvent
[BlackBoxEvent:R-HSA-167121] Addition of the third nucleotide on the nascent HIV-1 transcript - Homo sapiens
inferredFrom
[BlackBoxEvent:R-HSA-9613497] Unwinding DNA for the nascent transcript - Homo sapiens
input
[Complex:R-HSA-167101] HIV-1 transcription complex [nucleoplasm]
[SimpleEntity:R-ALL-9757634] NTP [nucleoplasm]
isInDisease
true
isInferred
true
literatureReference
[LiteratureReference:110387] Three transitions in the RNA polymerase II transcription complex during initiation.
[LiteratureReference:111262] Translocation after synthesis of a four-nucleotide RNA commits RNA polymerase II to promoter escape.
[LiteratureReference:9613486] DNA repair helicase: a component of BTF2 (TFIIH) basic transcription factor
maxDepth
1
modified
[InstanceEdit:9965811] Weiser, Joel, 2025年08月27日
name
Unwinding of DNA for the nascent HIV-1 transcript
output
[Complex:R-HSA-167101] HIV-1 transcription complex [nucleoplasm]
[SimpleEntity:R-ALL-113541] PPi [nucleoplasm]
precedingEvent
[Reaction:R-HSA-167134] Newly formed phosphodiester bond stabilized and PPi released - Homo sapiens
relatedSpecies
[Species:164493] Human immunodeficiency virus 1
releaseDate
2005年06月13日
releaseStatus
UPDATED
reviewStatus
[ReviewStatus:9821382] five stars
reviewed
[InstanceEdit:170419] Peterlin, BM, 2005年01月05日 00:00:00
schemaClass
BlackBoxEvent
species
[Species:48887] Homo sapiens
stId
R-HSA-9613498
summation
[Summation:9613495] The human BTF2 basic transcription factor (also called TFIIH...
updateTrackers
[UpdateTracker:9775385] Update Tracker - [BlackBoxEvent:9613498] Unwinding of DNA for the nascent HIV-1 transcript - v79:[add_removeInput]
Referrals
(updatedInstance)
[UpdateTracker:9775385] Update Tracker - [BlackBoxEvent:9613498] Unwinding of DNA for the nascent HIV-1 transcript - v79:[add_removeInput]
(hasEvent)
[Pathway:R-HSA-167162] RNA Polymerase II HIV Promoter Escape
(precedingEvent)
[BlackBoxEvent:R-HSA-167121] Addition of the third nucleotide on the nascent HIV-1 transcript
(inferredTo)
[BlackBoxEvent:R-HSA-9613497] Unwinding DNA for the nascent transcript
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