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The Ligand:GPCR:Gz complex dissociates Show undefined attributes

authored

[InstanceEdit:744889] Jupe, S, 2010年05月18日

category dissociation

compartment

created [InstanceEdit:751025] Jupe, S, 2010年05月19日

dbId 751024

displayName The Ligand:GPCR:Gz complex dissociates

edited

[InstanceEdit:813668] Jupe, S, 2010年05月26日

eventOf

[Pathway:R-HSA-418597] G alpha (z) signalling events - Homo sapiens

followingEvent

[Reaction:R-HSA-8981892] Active G alpha (z) binds RGS proteins - Homo sapiens
[Reaction:R-HSA-8982703] PKC binds active G alpha (z) - Homo sapiens
[Reaction:R-HSA-392133] G alpha (z) auto-inactivates by hydrolysing GTP to GDP - Homo sapiens
[Reaction:R-HSA-392064] G alpha (z) inhibits adenylate cyclase - Homo sapiens
[Reaction:R-HSA-8964241] G beta-gamma complex and PIP3 recruit BTK to membrane - Homo sapiens
[Reaction:R-HSA-398040] Gbeta:gamma activation of PLC beta - Homo sapiens
[Reaction:R-HSA-8964605] PAK1:ARHGEF6 complex binds G-protein beta-gamma complex - Homo sapiens
[Reaction:R-HSA-392295] Gbeta:gamma recruits PI3K gamma - Homo sapiens

input

[Complex:R-HSA-751030] ADRA2A-C:Catecholamine:Heterotrimeric G-protein Gz (active) [plasma membrane]

isChimeric false

isInDisease false

isInferred false

literatureReference

[LiteratureReference:427945] Dissociation of heterotrimeric g proteins in cells

maxDepth 1

modified [InstanceEdit:10867632] Weiser, Joel, 2025年08月27日

name

The Ligand:GPCR:Gz complex dissociates

orthologousEvent

output

precedingEvent

[Reaction:R-HSA-749453] Liganded Gz-activating GPCR acts as a GEF for Gz - Homo sapiens

releaseDate 2010年06月15日

reviewStatus [ReviewStatus:9821382] five stars

reviewed

[InstanceEdit:782850] D'Eustachio, P, 2010年05月21日

revised

[InstanceEdit:9012014] Varusai, Thawfeek, 2017年07月10日

schemaClass Reaction

species

[Species:48887] Homo sapiens

stId R-HSA-751024

summation

[Summation:804948] The classical view of G-protein signalling is that the G-pro...

updateTrackers

[UpdateTracker:9782270] Update Tracker - [Reaction:751024] The Ligand:GPCR:Gz complex dissociates - v59:[add_removeOutput]

Referrals

(updatedInstance)

[UpdateTracker:9782270] Update Tracker - [Reaction:751024] The Ligand:GPCR:Gz complex dissociates - v59:[add_removeOutput]

(precedingEvent)

(hasEvent)

[Pathway:R-HSA-418597] G alpha (z) signalling events

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