Reactome Pathway Database
Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Reactome Pathway Database
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
Schema
>
Reaction
>
Entries
dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK]
Show undefined attributes
Go to Details
catalystActivity
[CatalystActivity:73499] nucleoside monophosphate kinase activity of DTYMK dimer [cytosol]
catalystActivityReference
[CatalystActivityReference:9644065] nucleoside monophosphate kinase activity of DTYMK dimer [cytosol] Human thymidylate kinase. Purification, characterization, and kinetic behavior of the thymidylate kinase derived from chronic myelocytic leukemia
category
transition
compartment
[Compartment:70101] cytosol
created
[InstanceEdit:73446] Jassal, B, 2003年06月17日 09:00:25
dbId
73635
deleted
[Deleted:500000] Deletion of instance: 73631
[Deleted:500005] Deletion of instance: 110104
displayName
dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK]
eventOf
[Pathway:R-HSA-499943] Interconversion of nucleotide di- and triphosphates - Homo sapiens
followingEvent
[Reaction:R-HSA-482619] (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) - Homo sapiens
input
[SimpleEntity:R-ALL-113592] ATP [cytosol]
[DefinedSet:R-ALL-499997] dUMP, TMP [cytosol]
isInDisease
false
isInferred
false
literatureReference
[LiteratureReference:110105] Human thymidylate kinase. Purification, characterization, and kinetic behavior of the thymidylate kinase derived from chronic myelocytic leukemia
maxDepth
1
modified
[InstanceEdit:11064438] Weiser, Joel, 2025年08月28日
name
dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK]
phosphorylation of dUMP or TMP to dUDP or TDP
orthologousEvent
[Reaction:R-PFA-73635] dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] - Plasmodium falciparum
[Reaction:R-SCE-73635] dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] - Saccharomyces cerevisiae
[Reaction:R-SPO-73635] dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] - Schizosaccharomyces pombe
[Reaction:R-DDI-73635] dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] - Dictyostelium discoideum
[Reaction:R-CEL-73635] dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] - Caenorhabditis elegans
[Reaction:R-DME-73635] dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] - Drosophila melanogaster
[Reaction:R-GGA-73635] dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] - Gallus gallus
[Reaction:R-XTR-73635] dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] - Xenopus tropicalis
[Reaction:R-DRE-73635] dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] - Danio rerio
[Reaction:R-SSC-73635] dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] - Sus scrofa
[Reaction:R-BTA-73635] dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] - Bos taurus
[Reaction:R-CFA-73635] dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] - Canis familiaris
[Reaction:R-RNO-73635] dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] - Rattus norvegicus
[Reaction:R-MMU-73635] dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] - Mus musculus
output
[SimpleEntity:R-ALL-29370] ADP [cytosol]
[DefinedSet:R-ALL-499999] dUDP, TDP [cytosol]
precedingEvent
[Reaction:R-HSA-73596] dCMP + H2O => dUMP + NH4+ - Homo sapiens
[Reaction:R-HSA-73605] dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate - Homo sapiens
[Reaction:R-HSA-73632] thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] - Homo sapiens
releaseDate
2004年07月06日
reverseReaction
[Reaction:R-HSA-75126] dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK]
reviewStatus
[ReviewStatus:9821382] five stars
revised
[InstanceEdit:504064] D'Eustachio, P, 2010年02月05日
schemaClass
Reaction
species
[Species:48887] Homo sapiens
stId
R-HSA-73635
summation
[Summation:178320] Cytosolic deoxythymidylate kinase (DTYMK) catalyzes the reve...
updateTrackers
[UpdateTracker:9790956] Update Tracker - [Reaction:73635] dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] - v32:[add_removeInput, add_removeOutput, modifyText]
Referrals
(updatedInstance)
[UpdateTracker:9790956] Update Tracker - [Reaction:73635] dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] - v32:[add_removeInput, add_removeOutput, modifyText]
(replacementInstances)
[Deleted:500005] Deletion of instance: 110104
[Deleted:500000] Deletion of instance: 73631
(hasEvent)
[Pathway:R-HSA-499943] Interconversion of nucleotide di- and triphosphates
(precedingEvent)
[Reaction:R-HSA-482619] (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3)
© 2025
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text
Download
Close
AltStyle
によって変換されたページ
(->オリジナル)
/
アドレス:
モード:
デフォルト
音声ブラウザ
ルビ付き
配色反転
文字拡大
モバイル