Reactome Pathway Database

Schema > Reaction > Entries

histidine => urocanate + NH4+ Show undefined attributes

authored

[InstanceEdit:73677] D'Eustachio, P, 2003年06月24日 00:00:00

catalystActivity

[CatalystActivity:70898] histidine ammonia-lyase activity of HAL [cytosol]

catalystActivityReference [CatalystActivityReference:9643422] histidine ammonia-lyase activity of HAL [cytosol] Molecular characterization of histidinemia: identification of four missense mutations in the histidase gene

category transition

compartment

[Compartment:70101] cytosol

crossReference

dbId 70899

displayName histidine => urocanate + NH4+

edited

[InstanceEdit:73677] D'Eustachio, P, 2003年06月24日 00:00:00

eventOf

[Pathway:R-HSA-70921] Histidine catabolism - Homo sapiens

followingEvent

[Reaction:R-HSA-70903] urocanate + H2O => 4-imidazolone-5-propanoate - Homo sapiens

input

[SimpleEntity:R-ALL-29612] L-His [cytosol]

isInDisease false

isInferred false

literatureReference

[LiteratureReference:200265] Molecular characterization of histidinemia: identification of four missense mutations in the histidase gene

maxDepth 1

modified [InstanceEdit:10948619] Weiser, Joel, 2025年08月27日

name

histidine => urocanate + NH4+
L-histidine => NH4(+) + trans-urocanate

orthologousEvent

output

precedingEvent

[Reaction:R-HSA-8932851] PQLC2 transports L-Arg,L-His,L-Lys from lysosomal lumen to cytosol - Homo sapiens

releaseDate 2004年07月06日

reviewStatus [ReviewStatus:9821382] five stars

schemaClass Reaction

species

[Species:48887] Homo sapiens

stId R-HSA-70899

summation

[Summation:178862] Cytosolic histidine ammonia lyase (HAL) catalyzes the reacti...

updateTrackers

Referrals

(updatedInstance)

(hasEvent)

[Pathway:R-HSA-70921] Histidine catabolism

(precedingEvent)

[Reaction:R-HSA-70903] urocanate + H2O => 4-imidazolone-5-propanoate

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