Reactome Pathway Database

Schema > Complex > Entries

FGFR1c P252X mutant dimers bound to FGFs [plasma membrane] Show undefined attributes

catalystActivities

[CatalystActivity:2023453] protein tyrosine kinase activity of FGFR1c P252X mutant dimers bound to FGFs [plasma membrane]

compartment

[Compartment:876] plasma membrane

consumedByEvent

[Reaction:R-HSA-2023455] Autocatalytic phosphorylation of FGFR1c P252X mutant dimers - Homo sapiens

created [InstanceEdit:2050637] Rothfels, K, 2012年01月11日

crossReference

dbId 2050638

disease

displayName FGFR1c P252X mutant dimers bound to FGFs [plasma membrane]

hasComponent

inDisease true

includedLocation

[Compartment:984] extracellular region

isChimeric false

maxDepth 4

modified [InstanceEdit:9036004] Rothfels, Karen, 2018年01月26日

name

FGFR1c P252X mutant dimers bound to FGFs

producedByEvent

[Reaction:R-HSA-2023451] FGFR1c P252X mutants bind ligand with enhanced affinity - Homo sapiens

schemaClass Complex

species

[Species:48887] Homo sapiens

stId R-HSA-2050638

updateTrackers

Referrals

(updatedInstance)

(output)

[Reaction:R-HSA-2023451] FGFR1c P252X mutants bind ligand with enhanced affinity

(input)

[Reaction:R-HSA-2023455] Autocatalytic phosphorylation of FGFR1c P252X mutant dimers

(diseaseEntity)

[EntityFunctionalStatus:5654445] gain_of_function of FGFR1c P252X mutant dimers bound to FGFs [plasma membrane]

(physicalEntity)

[CatalystActivity:2023453] protein tyrosine kinase activity of FGFR1c P252X mutant dimers bound to FGFs [plasma membrane]

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