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Transport of MHC I:Nef:AP-1:PACS-1 Complex Show undefined attributes

authored

[InstanceEdit:200905] Gillespie, ME, 2007年07月25日 19:42:36

category transition

compartment

[Compartment:70101] cytosol

created [InstanceEdit:182282] Gillespie, ME, 2006年07月06日 21:32:37

crossReference

[DatabaseIdentifier:11944912] Mondo:0005109

dbId 182286

disease

[Disease:1660559] Human immunodeficiency virus infectious disease

displayName Transport of MHC I:Nef:AP-1:PACS-1 Complex

eventOf

[Pathway:R-HSA-164940] Nef mediated downregulation of MHC class I complex cell surface expression - Homo sapiens

followingEvent

[BlackBoxEvent:R-HSA-182263] Degradation of MHC I Complex - Homo sapiens

input

[Complex:R-HSA-182373] Nef:class I MHC complex:Ap-1:PACS-1 Complex [Golgi membrane]

isInDisease true

isInferred false

literatureReference

[LiteratureReference:182307] HIV-1 Nef disrupts MHC-I trafficking by recruiting AP-1 to the MHC-I cytoplasmic tail

maxDepth 1

modified [InstanceEdit:9830342] Matthews, Lisa, 2023年03月08日

name

Transport of MHC I:Nef:AP-1:PACS-1 Complex

output

[Complex:R-HSA-182254] Nef:class I MHC complex:AP-1:PACS-1 Complex [early endosome membrane]

precedingEvent

[Reaction:R-HSA-182279] Formation of MHC I:Nef:AP-1:PACS-1 Complex - Homo sapiens

relatedSpecies

[Species:164493] Human immunodeficiency virus 1

releaseDate 2007年08月21日

reviewStatus [ReviewStatus:9821382] five stars

reviewed

[InstanceEdit:201388] Skowronski, J, 2007年08月07日 14:33:41

schemaClass Reaction

species

[Species:48887] Homo sapiens

stId R-HSA-182286

summation

[Summation:182389] The complex of Nef, major histocompatibility complex class I...

Referrals

(hasEvent)

[Pathway:R-HSA-164940] Nef mediated downregulation of MHC class I complex cell surface expression

(precedingEvent)

[BlackBoxEvent:R-HSA-182263] Degradation of MHC I Complex

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