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Internalization of the CD8:Nef:AP-2 Complex:v-ATPase Complex Show undefined attributes

authored

[InstanceEdit:200905] Gillespie, ME, 2007年07月25日 19:42:36

category transition

compartment

[Compartment:70101] cytosol

created [InstanceEdit:182206] Gillespie, ME, 2006年07月06日 19:48:37

crossReference

[DatabaseIdentifier:11944912] Mondo:0005109

dbId 182198

disease

[Disease:1660559] Human immunodeficiency virus infectious disease

displayName Internalization of the CD8:Nef:AP-2 Complex:v-ATPase Complex

eventOf

[Pathway:R-HSA-182218] Nef Mediated CD8 Down-regulation - Homo sapiens

followingEvent

[BlackBoxEvent:R-HSA-182171] Degradation of CD8 - Homo sapiens

input

[Complex:R-HSA-182158] CD8:Nef:AP-2 Complex:v-ATPase Complex [plasma membrane]

isInDisease true

isInferred false

literatureReference

[LiteratureReference:182276] Human immunodeficiency virus Nef induces rapid internalization of the T-cell coreceptor CD8alphabeta

maxDepth 1

modified [InstanceEdit:9830342] Matthews, Lisa, 2023年03月08日

name

Internalization of the CD8:Nef:AP-2 Complex:v-ATPase Complex

output

[Complex:R-HSA-182230] Internalized CD8:Nef:Clathrin-Coated Pit Adapter Protein:v-ATPase [early endosome membrane]

precedingEvent

relatedSpecies

[Species:164493] Human immunodeficiency virus 1

releaseDate 2007年08月21日

reviewStatus [ReviewStatus:9821382] five stars

reviewed

[InstanceEdit:201388] Skowronski, J, 2007年08月07日 14:33:41

schemaClass Reaction

species

[Species:48887] Homo sapiens

stId R-HSA-182198

summation

[Summation:200898] The CD8alphabeta receptor is internalized via endocytosis.

Referrals

(precedingEvent)

[BlackBoxEvent:R-HSA-182171] Degradation of CD8

(hasEvent)

[Pathway:R-HSA-182218] Nef Mediated CD8 Down-regulation

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