Reactome Pathway Database

Schema > Reaction > Entries

HSPG2 (perlecan) degradation by MMP3, plasmin, (MMP12) Show undefined attributes

authored

[InstanceEdit:2426629] Jupe, S, 2012年08月08日

catalystActivity

[CatalystActivity:2534252] serine-type endopeptidase activity of MMP3, plasmin, (MMP12) [extracellular region]

category transition

compartment

[Compartment:984] extracellular region

created [InstanceEdit:1592294] Jupe, S, 2011年09月09日

dbId 1592314

displayName HSPG2 (perlecan) degradation by MMP3, plasmin, (MMP12)

edited

[InstanceEdit:4090280] Jupe, S, 2013年08月13日

eventOf

[Pathway:R-HSA-1474228] Degradation of the extracellular matrix - Homo sapiens

input

[EntityWithAccessionedSequence:R-HSA-1011570] HSPG2(22-4391) [extracellular region]

isChimeric false

isInDisease false

isInferred false

literatureReference

[LiteratureReference:1592399] The degradation of human endothelial cell-derived perlecan and release of bound basic fibroblast growth factor by stromelysin, collagenase, plasmin, and heparanases

maxDepth 1

modified [InstanceEdit:10867632] Weiser, Joel, 2025年08月27日

name

HSPG2 (perlecan) degradation by MMP3, plasmin, (MMP12)

orthologousEvent

output

releaseDate 2013年09月18日

reviewStatus [ReviewStatus:9821382] five stars

reviewed

[InstanceEdit:4088447] Ricard-Blum, Sylvie, 2013年08月13日

schemaClass Reaction

species

[Species:48887] Homo sapiens

stId R-HSA-1592314

summation

[Summation:1592408] HSPG2 protein (perlecan) consists of a core protein of molec...

Referrals

(hasEvent)

[Pathway:R-HSA-1474228] Degradation of the extracellular matrix

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