Reactome Pathway Database

Schema > Reaction > Entries

GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) Show undefined attributes

catalystActivity

[CatalystActivity:10710419] GMP reductase activity of GMPR tetramers [cytosol]

category transition

compartment

[Compartment:70101] cytosol

created [InstanceEdit:10680101] Weiser, Joel, 2025年08月27日

dbId 10710421

displayName GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2)

eventOf

[Pathway:R-GGA-74217] Purine salvage - Gallus gallus

evidenceType [EvidenceType:9965817] inferred by electronic annotation

inferredFrom

[Reaction:R-HSA-514604] GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2)

output

precedingEvent

[Reaction:R-GGA-74215] HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP - Gallus gallus

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:49591] Gallus gallus

stId R-GGA-514604

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-GGA-74217] Purine salvage

(inferredTo)

[Reaction:R-HSA-514604] GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2)

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