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• AACR Annual Meeting

* 2025 Press Releases

• New findings explain how a mutation in a cancer-related gene causes pulmonary fibrosis
• IGF2 Identified as a Critical Regulator of Early Adipose Tissue Development
• Long-standing mystery in molecular biology solved: Cells measure RNA tails with a molecular stopwatch
• Muscle’s master regulator moonlights as gene silencer
• How the ELAV protein shapes the brain’s unique circular RNA landscape
• Researchers identify mutations leading to reduced brain and body growth
• Understanding the genetic factors behind pediatric pilocytic astrocytoma and possible treatments
• DNA organization offers clues for advancing stem cell therapy
• Unraveling the Epigenetic Control of Hepatocyte-to-Bile Duct Cell Conversion
• Scientists Discover Protein Key to Bacteria's Survival in Extreme Environments
• G&D has New Editorial Leadership and an Expanded Scope

* 2024 Press Releases

• Potential New Treatment for Head and Neck Cancers

* 2023 Press Releases

• Novel Rett syndrome variant shines light on new screening strategies for therapies
• Identification of new signaling pathway advances cancer research
• DNA folding choices made in stem cells determine how genes are expressed in the brain
• Artificial Intelligence Catalyzes Gene Activation Research and Uncovers Rare DNA Sequences
• MYC inhibition in melanoma: preclinical promise and the unveiling of a prognostic gene signature
• An improved tRNA profiling method to uncover cancer signatures
• Interrupting cancer stem cell renewal promising in combatting glioblastoma

* 2022 Press Releases

• Cell fate determination: making sense out of nonsense
• Recently Discovered Protein Turbocharges Gene Expression
• LMS researchers identify unexpected nucleolar mechanism for gene regulation in early embryo development
• Penn Medicine Discovery Could Lead to Fewer Side Effects from a Diabetes Treatment
• A case of mistaken identity: Researchers unmask cellular source of Barrett’s esophagus
• Meiosis and crossing over: pairing and separating

* 2021 Press Releases

• New view of a transcriptional regulator driving melanoma proliferation
• When microRNAs Clash With Their Targets
• Scientists Pinpoint Protein’s Role in Critical Gene Expression
• Diabetes, obesity and ... the primary cilia?
• Featuring discoveries in breast cancer, multiple myeloma, cholangiocarcinoma, molecular imaging, gynecologic cancers and pancreatic cancer
• Unraveling the Mysterious Role of Centriolar Protein CEP120 in Joubert Syndrome, a Congenital Cerebellar Disorder
• Researchers Identify Core Genetic Networks Driving Human Embryonic Stem Cell Behavior
• UT Southwestern diabetes researchers show gene editing can turn storage fat cells into energy-burning fat cells
• New findings on the field of perinatal brain injury
• New insights on mechanism that could help treat muscle-related diseases
• PETISCO - a multi-tool for piRNA processing
• Researchers pinpoint how PARP inhibitors combat BRCA1 and BRCA2 tumor cells
• Pancreatic beta-cell boost in mice paves way for future diabetes treatments
• Three-layered control of mRNA tails
• Scientists provide new insight on how to stop transcription of cancer cells
• Ludwig Cancer Research study reveals even transient chromosomal mistakes can initiate cancer
• Discovery of circadian rhythm gene in mice could lead to breakthroughs in understanding those in humans
• New Class of Compounds Found to Block Coronavirus Reproduction
• Natural temperature fluctuations promote COOLAIR regulation of FLC
• How plants leave behind their parents’genomic baggage
• A New Potential Therapeutic Target for Metastatic Esophageal Cancer
• Researchers Engineer Much-Needed Mouse Model of a Rare Vascular Sarcoma
• Dueling Ants Vying to Become Replacement Queen
• Discovery Illuminates How Thyroid Hormone Dims Metabolism
• Understanding cellular clock synchronization
• XPO7 crucial to establish senescence and block tumour progression
• Essential Mechanisms for Proper Skin Development Identified
• Silencing by Crosstalk
• In Dueling Ants Vying to Become Replacement Queen, Behavioral and Molecular Cues Quickly Determine Who Will Win
• Proteins unspool DNA so cells can take on unique properties
• Scientists uncover new path toward treating a rare but deadly neurologic condition

* 2020 Press Releases

• Embryo’s self-destructing cells protect its future offspring
• Research Published in Genes and Development from Craig Thompson Lab
• Common diabetes drug reverses inflammation in the liver
• Kang finds keys to control the ‘driver of cancer’s aggressiveness’
• How Loss of Single Gene Fuels Deadly Childhood Brain Cancer
• Mutation leading to biological changes may play role in cancer
• New insights into drug resistance in small cell lung cancer
• Breakthrough discovery finds specific protein linked to intellectual disability and depression
• Gene defect influences tumor development in childhood brain tumors
• Novel regulators of myelin repair and regeneration discovered
• Novel approach reduces SCA1 symptoms in animal model
• New study shows cancer-causing ‘Frankengene’ mutation could be target for new drugs
• Researchers Identify Mechanisms That Make Skin a Protective Barrier
• Freeze! A regulatory protein puts messenger RNA in waiting position
• HELLS and PRDM9 form a pioneer complex to open chromatin at meiotic recombination hotspots
• Vernalization study defines additional phase in universal epigenetic mechanism
• Mutation’s role in blood cancers revealed by ideal team-up

* 2019 Press Releases

• Research reveals how muscles talk to the brain to regulate feeding behavior
• A life-or-death decision
• From Plants, UVA Extracts a Better Way to Determine What Our Genes Do
• University of Florida Health researchers gain new insight into muscular dystrophy gene
• An Experimental Anti-Cancer Drug Has an Unexpected Method of Attacking Cancer
• New research shows how cells control splicing, the process of removing extra pieces of RNA
• Bayreuth biochemists reveal insights into extraordinary regenerative ability
• New insights into the healing capacity of the heart
• MD Anderson study confirms protein as potential cause of most common type of pancreatic cancer
• UTSW researchers identify new pathway that controls fat formation
• Toronto researcher’s discovery sheds new light on the repair of chromosomes
• A key ‘kill switch’ in a gene-regulating protein group
• Gene Coding Error Found in Rare, Inherited Form of Lung-Scarring Disorder Linked to Short Telomeres
• The choreography of ribosomal DNA: its mobility allows its repair
• This combination targeted therapy may offer hope to infants diagnosed with a deadly type of leukemia
• Unlocking the secrets of an important regulator of human development
• MI-2β IS CRITICAL FOR PRODUCING B CELLS
• Cell biologists identify first events in stem cells becoming specialized cells needed for organ development
• Keeping the neighbours quiet: A lesson from C. elegans in using what you have to hand
• Researchers Identify Genetic Switch that Controls Conversion of Bad to Good Fat
• Prince Charming's kiss unlocking brain's regenerative potential?
• DNA damage: towards a better understanding of the repair process
• Removal of Gene Completely Prevents Development of Aggressive Pancreatic Cancer in Mice
• New role for a driver of metastatic cancers
• Scientists capture a ‘snapshot’ of bacterial stress-response regulator’s ‘recycling truck'
• Oscillation in muscle tissue
• Researchers Uncover Negative Regulator of RNA Exosome Complex
• Oncogenic risk arising from the loss of repeat silencing
• Max Planck researchers reveal how the DNA is made accessible for gene transcription
• Kick-starting the genome in early development
• Targeting an ‘Energy Crisis’ in the Treatment of Non-Small Cell Lung Cancer
• Discovery explains breast cancer cells’ ability to adapt, survive

* 2018 Press Releases

• Pediatric Leukemia ‘Super Drug’ could be developed in coming years
• Four proteins with ancestral functions combine in a complex that is essential for production of piRNAs
• Making sense of chromosomal chaos
• Rare disorder insight may aid therapy search
• Newfound Mechanism May Yield Ways to Counter Mistaken Immune Attack on Body
• Mutant Protein Tackles DNA Guardian to Promote Cancer Development
• Mutation Associated With ALS Causes Sugar-Starved Cells To Overproduce Lipids, Study Shows
• Inflammation can lead to circadian sleep disorders
• Large cells for tiny leaves
• Sequencing 20,000 Heart Cells Yields Insights into Cardiac Disease
• A protein prevents plants from premature flowering
• Analysis of Sea Squirt Embryo Reveals Key Molecules in Dopaminergic Neuron Differentiation
• Tweaking cells’ gatekeepers could lead to new way to fight cancer
• Study of Rare Cancer Yields Therapeutic Clues to Combat Drug Resistance
• Mass. General team finds how NF-2 gene mutations make cells hyper-responsive to growth factor signaling
• Groundwork for playing with the architecture of plants
• Research for the Ages (Of Cells)
• UTSW scientists identify new mechanisms underlying pediatric kidney cancer
• Progress toward improved Wilson’s disease drug
• Researchers discover new type of lung cancer
• Researchers peer inside cells to spy on cancer's on-off switch
• New light shed on how bone marrow niches keep stem cells thriving
• Blocking two enzymes could make cancer cells mortal
• Biologists Find Mechanisms that Control Where Transcription Factors Bind
• Scientists Find Missing Factor in Gene Activation
• Tracing DNA Deletions May Lead to New Cancer Therapies
• Study sheds light on why brain cancers become aggressive
• A potential setback in the personalised medicine of cancer
• Gene rhythm: how the circadian clock regulates 3D chromatin structure
• Intruder Alert: Cell Surveillance System Distinguishes Virus from Self
• A meiotic XPF–ERCC1-like complex recognizes joint molecule recombination intermediates to promote crossover formation
• Brain-gut communication in worms demonstrates how organs can work together to regulate lifespan
• Use of single particle cryo-EM for drug discovery
• Understanding a Fly’s Body Temperature May Help People Sleep Better
• Variant of the p53 Gene Increased Tumor Cell Metabolism
• Research offers new insight into workings of building blocks of life
• Highly Mutated Protein in Skin Cancer Plays Central Role in Skin Cell Renewal
• A Brain Chemical Blamed for Mental Decline in Old Age Could Hold Key to Its Reversal
• New tool tracks down distant regulators of gene expression, upends expectations
• Multipurpose enhancers and promoters in embryonic development
• Study reveals endocrine-producing microenvironment in embryonic pancreas
• Physiological protein blocks direct the Mre11–Rad50–Xrs2 and Sae2 nuclease complex to initiate DNA end resection

* 2017 Press Releases

• G-quadruplex regulates breast cancer-associated gene
• Multifunctional protein contributes to blood cell development
• Getting straight to the heart of the matter in stem cells
• Clock gene may hold answers to human brain evolution
• Women and Lung Cancer
• Brain tumour’s 'addiction' to common amino acid could be its weakness
• RNA stem-loop is crucial for the survival of male flies
• Scientists Identify Key Regulator of Male Fertility
• Targeting a Binding Protein in Mutated p53 Could Yield New Cancer Treatment Strategies
• Breast cancer study reveals dynamics of estrogen function
• Faulty cell signaling derails cerebral cortex development
• OMRF researchers identify gene mutation present in pair of diseases
• Embryos tune into the right channel
• Molecular Map Shows How to Disable Dangerous Bioweapon
• Why we did not evolve to live forever: Unveiling the mystery of why we age
• An Institute study finds a whole new role for one of the most famous proteins in cancer research
• Details in plant breeding barrier revealed
• New insights about wild-type p53 restoration across mutant landscapes and genotype specific sensitivity to Statins in Lung Cancers
• Two genes help older brain gain new cells
• A new role for an old actor could predict prostate cancer recurrence
• Disrupted prenatal RNA processing and myogenesis in congenital myotonic dystrophy
• Neuroblast differentiation during development and in neuroblastoma requires KIF1Bβ mediated transport of TRKA
• Searching for a crystal-clear picture of a molecular complex linked to cancer, other diseases
• Protein Network Signals Found to Drive Myeloid Leukemias
• UNC scientists show how DNA is accessed and used during the journey to maturation in fruit flies
• How mutations in a single gene alter the course of a deadly brain cancer
• How do human cells repair a broken zipper of DNA?
• Brain cancer study reveals therapy clues
• Uncovering the Genetic Mechanisms Driving Embryonic Development
• Scientists find skin cells at the root of balding, gray hair
• INTERFERing: the immune responses helping cancer cells resist treatment
• New Insights on Triggering Muscle Formation
• Plant's parent genes cooperate in shaping their child
• Massive Chromosome Fusions? Neurons Don’t Care
• STORM reveals the secrets of telomeres
• Key tool in DNA repair kit found
• Cellular jetlag seems to favor the development of diabetes
• Single tumor-initiating cells evade immune clearance by recruiting type II macrophages
• Unlocking crop diversity by manipulating plant sex
• Making the Stand-Ins Stand Out In Cancer
• Defective cell division process in the eye
• Study challenges potential pancreatic cancer target
• UC San Diego Biologists Unlock Code Regulating Most Human Genes
• Ludwig Study Reveals Why Cancer Cells Spread Within the Body
• UAlbany Researchers Discover New Form of Protein Regulation
• Small RNAs interact with newly synthesized transcripts to silence chromatin
• Kyoto University uncovers a genetic key to self-renewal of reproductive cells

* 2016 Press Releases

• Enzyme that regulates DNA repair may offer new precision treatments for breast and ovarian cancer
• What happens in the cell nucleus after fertilization
• Researchers find chemical tag that locks chromosomes together during meiosis
• Structural basis for snRNA recognition by the double WD40-repeat domain of Gemin5
• Coupled enhancer and coding sequence evolution of a homeobox gene shaped leaf diversit
• Nucleoporin-mediated regulation of cell identity genes
• Loss of Uhrf1 in neural stem cells leads to activation of retroviral elements and delayed neurodegeneration
• Neuron-type specific miRNA represses two broadly expressed genes to modulate an avoidance behavior in C. elegans
• Polarized regulatory landscape and Wnt responsiveness underlie Hox activation in embryos
• Temperature regulates splicing efficiency of the cold-inducible RNA-binding protein gene Cirbp
• Unbiased identification of signal-activated transcription factors by Barcoded Synthetic TAndem Repeat Promoter screening (BC-STAR-PROM)
• Direct interrogation of the role of H3K9 in metazoan heterochromatin function
• A senescence secretory switch mediated by PI3K/AKT/mTOR activation controls chemoprotective endothelial secretory responses
• Autophagy Provides Metabolic Substrates to Maintain Energy Charge and Nucleotide Pools in Ras-Driven Lung Cancer Cells
• Penn study sheds light on biology of leading cause of liver failure.
• Mass. General study links developmental and lipid handling pathways in C. elegans.
• Modeling invasive lobular breast carcinoma by CRISPR/Cas9-mediated somatic genome editing of the mammary gland.
• The adrenal capsule is a signalling centre controlling cell renewal and zonation through Rspo3.
• Researchers at ULB develop new techniques to assess the fate of stem cells in vivo.

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