Rate of infusion
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In pharmacokinetics, the rate of infusion (or dosing rate) refers not just to the rate at which a drug is administered, but the desired rate at which a drug should be administered to achieve a steady state of a fixed dose which has been demonstrated to be therapeutically effective.
Abbreviations include Kin,[1] K0,[2] or R0.
It can be calculated as the steady-state concentration in the plasma multiplied by the clearance:
{\displaystyle \textstyle K_{in}=C_{ss}\cdot CL}
References
[edit ]- ^ "Cp vs time - iv infusion". Archived from the original on 2008年04月25日.
- ^ "Chapter 15.2 - Continuous IV Infusion - Steady State". Archived from the original on 2013年10月22日.
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