Mycobacterium conceptionense

Mycobacterium conceptionense is a non pigmented rapidly growing mycobacterium was first isolated from wound liquid outflow, bone tissue biopsy, and excised skin tissue from a 31-year-old woman who suffered an accidental open right tibia fracture and prolonged stay in a river. Etymology: conceptionense, pertaining to Hôpital de la Conception, the hospital where the first strain was isolated.

Microscopy

• Acid-fast and gram-positive bacilli.

Colony characteristics

• Colonies are non pigmented.

Physiology

• Colonies appear on 5% sheep blood agar, Middlebrook 7H10 agar, and egg-based Lowenstein-Jensen slants in 2 to 5

days at temperatures between 25 and 37 °C, optimally at 30 °C. No growth occurs at 42 °C.

• The type strain is susceptible in vitro to imipenem, minocycline, doxycycline, clarithromycin, erythromycin, azithromycin, amikacin, ciprofloxacin, ofloxacin, sparfloxacin, and amoxicillinclavulanate and resistant to penicillin, amoxicillin, and vancomycin.

Differential characteristics

• M. conceptionense shares 99.7% 16S rRNA (4-bp difference) and 97.0% rpoB gene sequence similarity with Mycobacterium porcinum , the nearest species.

• This species is associated with post traumatic osteitis.

• Strain D16 = CCUG 50187 = CIP 108544

• Adékambi, T.; et al. (2006). "Description of Mycobacterium conceptionense sp. nov., a Mycobacterium fortuitum group organism isolated from a posttraumatic osteitis inflammation". J. Clin. Microbiol. 44: 1268–1273. doi:10.1128/JCM.44.4.1268-1273.2006. PMC 1448615 . PMID 16597850.

• Type strain of Mycobacterium conceptionense at BacDive - the Bacterial Diversity Metadatabase

• Acid-fast bacilli
• Nontuberculous mycobacteria
• Bacteria described in 2006
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