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DNAJC7

From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
DNAJC7
Identifiers
Aliases DNAJC7 , DJ11, DJC7, TPR2, TTC2, DnaJ heat shock protein family (Hsp40) member C7
External IDsOMIM: 601964; MGI: 1928373; HomoloGene: 68306; GeneCards: DNAJC7; OMA:DNAJC7 - orthologs
Gene location (Human)
Chromosome 17 (human)
Chr. Chromosome 17 (human) [1]
Band 17q21.2Start41,976,421 bp [1]
End42,021,376 bp [1]
Gene location (Mouse)
Chromosome 11 (mouse)
Chr. Chromosome 11 (mouse)[2]
Band 11 D|11 63.47 cMStart100,473,644 bp [2]
End100,511,014 bp [2]
RNA expression pattern
Bgee
Human Mouse (ortholog)
  • nucleus accumbens

  • caudate nucleus

  • right frontal lobe

  • anterior pituitary

  • monocyte

  • mucosa of transverse colon

  • apex of heart

  • cingulate gyrus

  • Brodmann area 9

  • anterior cingulate cortex
  • tail of embryo

  • neural layer of retina

  • ventricular zone

  • genital tubercle

  • superior frontal gyrus

  • thymus

  • ganglionic eminence

  • cerebellar cortex

  • primary visual cortex

  • trigeminal ganglion
More reference expression data
BioGPS
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

7266

56354

Ensembl

ENSG00000168259

ENSMUSG00000014195

UniProt

Q99615

Q9QYI3

RefSeq (mRNA)

NM_001144766
NM_003315

NM_019795
NM_001378962
NM_001378963

RefSeq (protein)

NP_001138238
NP_003306

NP_062769
NP_001365891
NP_001365892

Location (UCSC)Chr 17: 41.98 – 42.02 Mb Chr 11: 100.47 – 100.51 Mb
PubMed search[3] [4]
Wikidata

DnaJ homolog subfamily C member 7 is a protein that in humans is encoded by the DNAJC7 gene.[5] [6] [7]

Interactions

[edit ]

DNAJC7 has been shown to interact with RAD9A.[8]

References

[edit ]
  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000168259Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000014195Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Murthy AE, Bernards A, Church D, Wasmuth J, Gusella JF (Nov 1996). "Identification and characterization of two novel tetratricopeptide repeat-containing genes". DNA Cell Biol. 15 (9): 727–35. doi:10.1089/dna.199615727. PMID 8836031.
  6. ^ Ohtsuka K, Hata M (Jan 2001). "Mammalian HSP40/DNAJ homologs: cloning of novel cDNAs and a proposal for their classification and nomenclature". Cell Stress Chaperones. 5 (2): 98–112. doi:10.1379/1466-1268(2000)005<0098:mhdhco>2.0.co;2 (inactive 12 July 2025). PMC 312896 . PMID 11147971.{{cite journal}}: CS1 maint: DOI inactive as of July 2025 (link)
  7. ^ "Entrez Gene: DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7".
  8. ^ Xiang SL, Kumano T, Iwasaki SI, Sun X, Yoshioka K, Yamamoto KC (2001). "The J domain of Tpr2 regulates its interaction with the proapoptotic and cell-cycle checkpoint protein, Rad9". Biochem. Biophys. Res. Commun. 287 (4): 932–40. doi:10.1006/bbrc.2001.5685. hdl:2297/1794 . PMID 11573955. S2CID 20694221.

Further reading

[edit ]
Chaperones/
protein folding
Heat shock proteins/
Chaperonins
Other
Protein targeting
Ubiquitin
(ubiquitylation)
Ubiquitin-like proteins
(UBL)
SUMO protein
(SUMOylation)
  • E2 SUMO-conjugating enzyme
Other


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