Clorexolone

Chemical compound

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Pharmaceutical compound

Clorexolone
Clinical data

ATC code	C03BA12 (WHO )
Identifiers
IUPAC name 6-chloro-2-cyclohexyl-3-oxo-2,3-dihydro- 1H-isoindole-5-sulfonamide
CAS Number	2127年01月7日
PubChem CID	16473
ChemSpider	15615
UNII	Q2PLT3FS05
KEGG	D01436
ChEMBL	ChEMBL2106167
CompTox Dashboard (EPA)	DTXSID4057683 Edit this at Wikidata
ECHA InfoCard	100.016.675 Edit this at Wikidata
Chemical and physical data
Formula	C₁₄H₁₇ClN₂O₃S
Molar mass	328.81 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES O=S(=O)(c1cc2C(=O)N(Cc2cc1Cl)C3CCCCC3)N

Clorexolone is a low-ceiling sulfonamide diuretic.^[1]

References

^ Gartha IV (December 1967). "Clorexolone: a new oral diuretic". Applied Therapeutics. 9 (12): 998–1001. PMID 4865373.

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Thiazide-likes (primarily DCT)	Chlortalidone Clofenamide Clopamide Clorexolone Fenquizone Indapamide (+telmisartan and amlodipine) Mefruside Meticrane Metolazone Quinethazone Xipamide

ESC blockers	Amiloride ^# Benzamil Triamterene
Aldosterone antagonists	Spirolactones Spironolactone ^# Canrenone Eplerenone Potassium canrenoate Nonsteroidal Finerenone