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This study reveals that during human gait development, neuromotor modules (muscle synergies) and limb biomechanical properties co-evolve toward bilateral symmetry, which enhances locomotor stability. By combining longitudinal EMG, kinematic, and neuromusculoskeletal modeling data from infants, adults, and elders, the authors demonstrate that functional symmetrization of these modules underlies efficient and stable gait control across the lifespan.
Biotin methyl ester (BME) acts as a biotin prodrug that easily penetrates cells and is converted into biotin, enhancing the utility of biotin–streptavidin technology for diverse applications in living cells.
Chromosome-level triploid genome assembly of parthenogenetic H. longicornis reveals autopolyploid origin, key embryogenesis genes, and pathogen tolerance in its global expansion context.
Visualization of endogenous exosomes in the zebrafish lens reveals their dynamic roles in intercellular communication and development, with Syntenin-a–regulated exosome biogenesis influencing lens cell differentiation.
In this Q&A, we ask Benjamin Rosman about his career, the role of biology in the development of robotics and AI, and his actions to establish Africa as a global leader in foundational AI research.
In this article, Bhuminder Singh tells us about the development of 3D colorectal cancer cell culture by their lab as a tool to identify therapeutic drugs.
In January, we thank Joanna Nakonieczna, Intercollegiate Faculty of Biotechnology of University of Gdańsk and Medical University of Gdańsk, Poland, for her invaluable contributions to peer review.
The authors show that the plant-derived small-molecule compound Nimbolide can bind to and inhibit the innate immune sensor NLRP3, thereby, preventing acute respiratory distress syndrome and ulcerative colitis in mice.
Single-cell analysis of B cells and their niches reveals gene regulation dynamics, developmental heterogeneity, cell-cell interactions, and age-associated B cell subpopulations with distinct secretory phenotypes.
Fatty liver disease may harm the brain by starving it of a protective fuel. This study shows that restoring this fuel, BHB, can rescue memory and brain health, revealing a direct liver-brain link and a promising treatment target.
Computationally designed TRI2-2 miniprotein inhibitor broadly neutralizes multiple SARS-CoV-2 Omicron variants and confers post-exposure protection in mice against BQ.1.1, XBB.1.5, and BA.2.86 challenge when administered intranasally.
Gene and allele-specific expression in the electric organ interpret the development of the electric signal in African weakly electric fish may relative to the expression an inward potassium channel gene KCNJ2.
Systematic evaluation of Procrustes alignment shows how using more functional gradients alters principal gradients and affects identifiability, highlighting key implications for individual-level fMRI analyses.
This review discusses what is known about Mincle regulation: where and when it is expressed, how it binds its ligands, and the factors involved in modulating its signaling.
This review summarizes how molecular chaperones enable structures of small inactive-state GPCRs by improving particle alignment and effective molecular weight, delivering high-resolution cryo-EM insights and guiding community decisions on stabilization strategies.
This review summarizes how catabolic rewiring lets tumors harvest fuels and why dietary interventions have limited impact on nutrient supply but meaningful endocrine and immune benefits that burden tumor metabolism and complement standard care.
Our review summarizes recent advances in understanding the diverse roles of nuclear lamins in mitosis and discusses how their dysregulation - observed in several diseases - could affect this essential process required for faithful genome inheritance.
In this LGBTQIA+ STEM Day, we spoke to Geo Santiago-Martinez (he/him), an Assistant Professor at the University of Connecticut working on Microbial Ecophysiology, and a member of the Advancing Queer and Transgender Equity in Science (AQTES) consortium.
To commemorate LGBTQIA+ STEM Day this year, Communications Biology is reaching out to discuss their personal and professional experiences in research. In this Q&A, we are talking to Dr. Fabrice Roux, a CNRS research director at Toulouse in France, who works on plant adaptation at the intersection of ecological genomics, quantitative genetics, and molecular biology.
Benjamin Rosman is a Professor in the School of Computer Science and Applied Mathematics at the University of the Witwatersrand (Wits), in Johannesburg (South Africa), where he runs the Robotics, Autonomous Intelligence and Learning (RAIL) Laboratory. Since November 2024, he is also the founding Director of the Machine Intelligence and Neural Discovery (MIND) Institute at Wits, focused on the fundamental science of intelligence in machines, humans, and animals. Dr. Rosman is a leading voice in artificial intelligence (AI) research and has received prestigious awards for his contributions to advancing AI in Africa and beyond. In August 2025, he was named in TIME’s annual list of the 100 most influential people in AI. In this Q&A, we discussed his career journey, the role of biology in the development of robotics and AI, and his actions to establish Africa as a global leader in foundational AI research.
Francesco Mattia Rossi is an Associate Professor in the Laboratorio de Neurociencias at the Facultad de Ciencias - Universidad de la República in Montevideo (Uruguay), investigating the mechanisms of neuronal plasticity in the visual cortex. In addition to his faculty role, Dr. Rossi chairs the Federation of Latin American and Caribbean Neuroscience Societies. In this Q&A, he discusses his career journey and his engagement in promoting (neuro)science research and education in Latin America and the Caribbean.
Ingrid Eftedal is a senior scientist at Norwegian University of Science and Technology Department of Circulation and Medical Imaging, Norway, and a leading expert in baromedicine. In this Q&A, we talk about what started her career and the challenges of conducting niche research.
In this interview, marine biologist Jasmin Graham shares about her experience building grassroots change in science, navigating exclusionary spaces and what it means to foster belonging in the ocean sciences.