#README for FDR-regression repository

This folder contains the code to fully reproduce the simulations and data analysis in the paper "A regression framework for the proportion of true null hypotheses" by SM Boca and JT Leek.

##simulations.Rnw

This file contains the code to generate Figures 1 and 2.

##diff_samp_size_variances.Rnw

This file contains the code to generate the results for Table 2.

##data_analysis_GIANT.Rmd

This file contains the code to perform the data analysis and generate Figures 3 and 4. The data must first be downloaded from https://www.broadinstitute.org/collaboration/giant/index.php/GIANT_consortium_data_files#GWAS_Anthropometric_2015_BMI

##simulations.pdf

Output of simulations.Rnw

##diff_samp_size_variances.pdf

Output of diff_samp_size_variances.Rnw

##data_analysis_GIANT.html

Output of data_analysis_GIANT.html

##figures (directory)

Figures generated by the *.Rnw and *.Rmd files and used in the paper.