NpSearch: Search for Neuropeptides
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Updated
Jan 26, 2017 - Ruby
NpSearch: Search for Neuropeptides
This repository contains the datasets, scripts, and analyses for the Laboratory of Bioinformatics II course project, focusing on the prediction of secretory signal peptides.
A comprehensive protein analysis platform that combines motif detection with 3D structure validation using AlphaFold2 confidence scores. Designed for cancer biology research, drug discovery, and functional genomics.
To predict cryptic cleavage sites in proteins with non-canonical signal peptides
Standalone Python package for annotating protein sequences with biological and physicochemical properties (iFeature, IEDB, SignalP) for reverse vaccinology. Extracted from VacSol-ML(ESKAPE); supports multi-allele MHC-I/II epitope prediction. Provides both a Python API and a CLI
A protein ML pipeline for eukaryotic signal peptide prediction using UniProtKB, MMseqs2, classical baselines, SVM biochemical features, and a CNN-BiLSTM classifier on ESM-2 protein embeddings.
A re-built convolutional neural network from paper「DeepSig: deep learning improves signal peptide detection in proteins」
Signal peptide prediction using deep learning. SandwichSP uses a CNN-LSTM-CRF architecture with ProtT5 embeddings to predict signal peptides and their cleavage sites in protein sequences.
Origin mechanisms of SAARs – use case of L-SAARs in signal peptides among higher Eukaryotes
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