🌱 Designing CRISPRi experiments in bacteria
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May 14, 2026 - Python
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crispri
Here are 10 public repositories matching this topic...
What a genome-scale CRISPRi screen can and cannot discover. 50 Hallmark programs x 9,837 knockdowns in K562. Four evaluations, three negative, all four reported.
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Sep 8, 2026 - HTML
Reproducible CRISPRi/Perturb-seq analysis of an ENTPD1/CD39 T-cell program in rheumatoid arthritis and methotrexate treatment
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Jul 28, 2026 - Python
Adversarial-debate LLM agent for predicting CRISPRi perturbation effects on gene expression (Genentech MLGenX BioReasoning Challenge)
bioinformatics computational-biology gene-expression kaggle-competition crispri vllm llm-agents agentic-ai perturbation-biology
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Jul 21, 2026 - Python
Phenotypic screening of a CRISPRi strain library [Smith et 2017, Mol Syst Biol (2017)13:913] for acetic acid tolerance targeting essential and respiratory essential genes in Saccharomyces cerevisiae
yeast phenomics high-throughput-screening saccharomyces-cerevisiae stress-tolerance essential-genes scan-o-matic bioscreen acetic-acid crispri
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Oct 9, 2021 - R
Repository containing the code and methods for Bosch & DeJesus et al. 2021
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Sep 8, 2025 - R
AI-assisted platform for designing CRISPR experiments — from target selection to bench-ready protocols
python bioinformatics crispr gradio base-editing gene-editing guide-rna research-tools crispri prime-editing crispor crispra
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Apr 13, 2026 - Python
PyTorch classifier predicting CRISPRi guide identity from single-cell expression (Adamson et al. 2016 Perturb-seq)
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Jul 28, 2026 - Python
Computational design and adversarial validation of synthetic gene circuits targeting PDAC transcription factors, trained from scratch on real public genomics data
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Aug 10, 2026 - Python
Figure code and data for Johnson et al. 2021, J Am Chem Soc 143(31):12003-12013, doi:10.1021/jacs.1c02622. CRISPRi chemical genomics identifying IleRS as the target of thiomarinol
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Aug 8, 2026 - R
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