Biomedical Data Science group

CRISPR-Cas9 sgRNA design across many genomes

*HaploCrackling* -- The Crackling-based method for variant-aware, whole-genome CRISPR-Cas9 target detection

CRISPR, faster, better – The Crackling method for whole-genome target detection

Whole-genome CRISPR target detection, implementing the method described in Sunagawa et al., "Mammalian Reverse Genetics without Crossing Reveals Nr3a as a Short-Sleeper Gene", Cell Reports 14(3)662-677, 2016

Supplementary data for "A Benchmark of Computational CRISPR-Cas9 Guide Design Methods"

Identification of allele-specific CRISPR targets in the K562 cell line.

Algorithm for module identification in biological networks