Organ physics substrate — cardiac pacemaker simulation with autonomic modulation, integer-only ion channel dynamics, and real-time vital sign diagnostics

Biological neuron pool substrate — LIF neurons, CSR synapses, eligibility traces, three-factor plasticity

Central nervous system white matter tracts — association, commissural, and projection fiber bundles with myelination-dependent conduction, chemical modulation, and Hebbian plasticity

C. elegans nervous system — 302 undifferentiated neurons develop into a functional worm brain through imaginal disc developmental phases

Distributed representational memory — signal-vector banks with typed edges

Peripheral nervous system substrate — bidirectional fiber tracts with labeled-line encoding, Weber-law sensory quantization, and use-dependent adaptation

Temporal field substrate - ring buffer with decay and pub/sub for cognitive architectures. The brain does not poll - one spark cascades.

Universal CLI for managing Engram, Cartridge, DataSpool, and DataCard archives - offline-first, cryptographically verified knowledge preservation

Profile-driven markup language for structured knowledge. CML (inspired by XML) for legal documents, API docs, and narrative content. Deterministic transforms to JSON/MD/HTML/TXT, VS Code integration, schema validation.