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YY1AP1

From Wikipedia, the free encyclopedia

Protein-coding gene in the species Homo sapiens

YY1AP1

Identifiers

YY1AP1 , HCCA1, HCCA2, YAP, YY1AP, YY1 associated protein 1, GRNG

External IDs

OMIM: 607860; HomoloGene: 130398; GeneCards: YY1AP1; OMA:YY1AP1 - orthologs

Gene location (Human)
Chromosome 1 (human)
Chr.	Chromosome 1 (human) ^[1]
Chromosome 1 (human) Genomic location for YY1AP1 Genomic location for YY1AP1
Band	1q22	Start	155,659,443 bp ^[1]
Band	1q22	End	155,689,000 bp ^[1]

RNA expression pattern

Human	Mouse (ortholog)
Top expressed in Achilles tendon oocyte secondary oocyte right testis left testis blood corpus callosum gastrocnemius muscle mucosa of pharynx saphenous vein	n/a
More reference expression data

More reference expression data

Gene ontology
Molecular function	protein binding
Cellular component	cytoplasm nucleus fibrillar center Ino80 complex nucleoplasm nucleolus
Biological process	regulation of transcription, DNA-templated transcription, DNA-templated cell differentiation regulation of cell cycle cell population proliferation
Sources:Amigo / QuickGO

Species

Human

Mouse


55249


n/a


ENSG00000163374


n/a


Q9H869


n/a

RefSeq (mRNA)

NM_001198899 NM_001198900 NM_001198901 NM_001198902 NM_001198903
NM_001198904 NM_001198905 NM_001198906 NM_018253 NM_139118 NM_139119 NM_139120 NM_139121

n/a

RefSeq (protein)

NP_001185828 NP_001185829 NP_001185830 NP_001185831 NP_001185832
NP_001185833 NP_001185834 NP_001185835 NP_060723 NP_620829 NP_620830 NP_620832

n/a

Location (UCSC)

Chr 1: 155.66 – 155.69 Mb

n/a

PubMed search

^[2]

n/a

View/Edit Human

YY1-associated protein 1 is a protein that in humans is encoded by the YY1AP1 gene.^[3]^[4]

The encoded gene product presumably interacts with YY1 protein; however, its exact function is not known. Alternative splicing results in multiple transcript variants encoding different isoforms.^[4]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000163374 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Wang ZX, Wang HY, Wu MC (Nov 2001). "Identification and characterization of a novel human hepatocellular carcinoma-associated gene". Br J Cancer. 85 (8): 1162–7. doi:10.1054/bjoc.2001.2059. PMC 2375167 . PMID 11710830.
^ ^a ^b "Entrez Gene: YY1AP1 YY1 associated protein 1".

Further reading

Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948 . PMID 11076863.
Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072 . PMID 11230166.
Wang Z, Hu G, Wang H, Wu M (2002). "[Clone of a novel liver cancer associated gene and analysis of the secondary structures of the predicted protein]". Zhonghua Gan Zang Bing Za Zhi. 10 (1): 25–7. PMID 11856496.
Zeng JZ, Wang HY, Chen ZJ, et al. (2002). "Molecular cloning and characterization of a novel gene which is highly expressed in hepatocellular carcinoma". Oncogene. 21 (32): 4932–43. doi:10.1038/sj.onc.1205652. PMID 12118372. S2CID 30899427.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899 . PMC 139241 . PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285 . PMID 14702039.
Wang CY, Liang YJ, Lin YS, et al. (2004). "YY1AP, a novel co-activator of YY1". J. Biol. Chem. 279 (17): 17750–5. doi:10.1074/jbc.M310532200 . PMID 14744866.
Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. Bibcode:2004PNAS..10112130B. doi:10.1073/pnas.0404720101 . PMC 514446 . PMID 15302935.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928 . PMID 15489334.
Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930 . PMID 15489336.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501 . PMID 16381901.
Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. Bibcode:2006Natur.441..315G. doi:10.1038/nature04727 . PMID 16710414.
Lim J, Hao T, Shaw C, et al. (2006). "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration". Cell. 125 (4): 801–14. doi:10.1016/j.cell.2006年03月03日2 . PMID 16713569. S2CID 13709685.

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