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User:Pabnau/sandbox/Jay Shendure

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American geneticist
Jay Shendure (Placeholder)
Born1974 (age5152) [1]
Education
Knownfor
  • Next-generation sequencing
  • Exome sequencing
  • Single-cell combinatorial indexing [4]
  • Molecular recording [5]
Awards
Scientific career
Fields
Institutions
Thesis Multiplex genome sequencing and analysis [16] (2005)
George M. Church [17]
Otheracademic advisors
Lee M. Silver [18]
Websiteshendurelab.github.io


Jay Shendure is an American scientist and human geneticist at the University of Washington. He is a professor in the Department of Genome Sciences at the University of Washington School of Medicine [19] and an Affiliate Investigator in the Human Biology Division at the Fred Hutchinson Cancer Research Center.[20] Shendure's research is focused on developing and applying new technologies in genomics. In 2005, his doctoral research with George M. Church resulted one of the first successful proof-of-concepts of next-generation DNA sequencing.[21] [22] [23] Shendure's research group at the University of Washington pioneered exome sequencing and its application to Mendelian disorders,[23] [24] a strategy that has been applied to identify hundreds of disease-causing genes.[25] Other notable accomplishments of Shendure's laboratory include the first whole genome sequencing of a human fetus using samples obtained non-invasively from the parents,[26] [27] and the sequencing of the HeLa genome in agreement with Henrietta Lacks' family.[28] [29] [30]

Early life and education

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Shendure graduated summa cum laude from Princeton University in 1996 and completed a Fulbright scholarship at Pune, India, in 1997. He then entered the Medical Scientist Training Program at Harvard Medical School and received his Ph.D. in 2005 and his M.D. in 2007. He joined the faculty at the Department of Genome Sciences at the University of Washington in 2007 and was tenured as an associate professor four years later in 2011.[23]

Career and Research

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Awards and Honors

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Shendure is a 2006 recipient of the TR35 Young Innovator Award from MIT Technology Review ,[31] the Curt Stern Award from the American Society of Human Genetics in 2012,[32] the FederaPrijs from the Federation of Dutch Medical Scientific Societies in 2013,[33] a National Institutes of Health Director's Pioneer Award in 2013,[34] and a Howard Hughes Medical Investigator Award. He is also the founding Scientific Director of the Brotman-Baty Institute established in 2017 through a gift from Jeffrey H. and Susan Brotman, and Daniel R. and Pamela L. Baty.

Personal Life

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His parents immigrated to the US from India in the late 1960s.[35] Jay Shendure was born in 1974 in Solon, Ohio.[2] He got married and has three kids,[36] [35] and is a marathoner.[35]

References

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  1. "Jay Shendure". MIT Technology Review. Retrieved 2026年07月27日.
  2. 1 2 Zunt, Dick (1992, May 27). "Solon is Coming on Strong". The Plain Dealer
  3. "Jay Shendure – NAS". National Academy of Sciences/. Retrieved 2026年08月09日.
  4. Cao, Junyue; Packer, Jonathan S.; Ramani, Vijay; Cusanovich, Darren A.; Huynh, Chau; Daza, Riza; Qiu, Xiaojie; Lee, Choli; Furlan, Scott N.; Steemers, Frank J.; Adey, Andrew; Waterston, Robert H.; Trapnell, Cole; Shendure, Jay (2017年08月18日). "Comprehensive single-cell transcriptional profiling of a multicellular organism". Science. 357 (6352): 661–667. doi:10.1126/science.aam8940. PMC 5894354 . PMID 28818938.
  5. Zimmer, Carl (2024年11月25日). "'DNA Typewriters' Can Record a Cell's History". The New York Times. ISSN 0362-4331 . Retrieved 2026年07月27日.
  6. "National Academy of Medicine Elects 100 New Members - NAM". nam.edu. 2025年10月20日. Retrieved 2026年07月27日.
  7. "Fellows". NAI. Retrieved 2026年07月27日.
  8. "Fellows". NAI. Retrieved 2026年07月27日.
  9. "Jay Shendure | Richard Lounsbery Foundation". Lounsbery Foundation. Retrieved 2026年07月27日.
  10. "AAAS Honors Accomplished Scientists as 2018 Elected Fellows | American Association for the Advancement of Science (AAAS)". American Association for the Advancement of Science (AAAS). Retrieved 2026年07月27日.
  11. NIH Pioneer award recipients, 2013
  12. Eichler, Evan E. (2013年03月07日). "2012 introduction to the Curt Stern Award: Jay Shendure". American Journal of Human Genetics. 92 (3): 338–339. doi:10.1016/j.ajhg.2012年11月01日9. ISSN 1537-6605. PMC 3591784 . PMID 23472755.
  13. 1 2 "Jay Shendure – UW Genome Sciences" . Retrieved 2026年07月28日.
  14. "Jay Shendure, MD, PhD | Investigator Profile | 2015-Present". www.hhmi.org. Retrieved 2026年07月28日.
  15. 1 2 "Shendure Lab | Allen Institute". alleninstitute.org. Retrieved 2026年07月28日.
  16. https://www.proquest.com/docview/305001213?sourcetype=Dissertations%20&%20Theses Multiplex genome sequencing and analysis
  17. "Jay Shendure at National Human Genetics Research Institute". www.genome.gov. Retrieved 2026年07月28日.
  18. Jay, Shendure (1996). "Genetic Mapping of Quantitative Trait Loci Controlling Alcohol Preference Behavior in Inbred Mouse Strains".
  19. "Jay Shendure". UW Genome Sciences. Retrieved 2014年02月04日.
  20. "Jay Shendure, MD, PhD". Fred Hutchinson Cancer Research Center . Retrieved 2014年02月04日.
  21. Nicholas Wade. "2 New Methods to Sequence DNA Promise Vastly Lower Costs". The New York Times . Retrieved 2014年02月04日.
  22. "Milestone 18 : Nature Milestones in DNA". Nature. 2007年10月15日. Retrieved 2014年02月04日.
  23. 1 2 3 Eichler, E. E. (2013). "2012 Introduction to the Curt Stern Award: Jay Shendure". The American Journal of Human Genetics. 92 (3): 338–339. doi:10.1016/j.ajhg.2012年11月01日9. PMC 3591784 . PMID 23472755.
  24. Elie Dolgin (2009年11月13日). "Selective sequencing solves a genetic mystery : Nature News". Nature. Retrieved 2014年02月04日.
  25. Jocelyn Kaiser (2010年11月12日). "Affordable 'Exomes' Fill Gaps in a Catalog of Rare Diseases". Science. 330 (6006): 903. Bibcode:2010Sci...330..903K. doi:10.1126/science.330.6006.903 . PMID 21071642.
  26. Andrew Pollack. "DNA Blueprint for Fetus Built Using Tests of Parents". The New York Times . Retrieved 2014年02月04日.
  27. Lopatto, Elizabeth (2012年06月06日). "Blood-Saliva Analysis May Replace Invasive Prenatal Test". Bloomberg. Retrieved 2014年02月04日.
  28. "After Decades of Research Henrietta Lack's Family is Asked for Consent". The New York Times . Retrieved 2014年02月04日.
  29. "Deal done over HeLa cell line : Nature News & Comment". Nature. 2013年08月07日. Retrieved 2014年02月04日.
  30. Hudson, Kathy L.; Collins, Francis S. (2013). "Biospecimen policy: Family matters". Nature. 500 (7461): 141–142. Bibcode:2013Natur.500..141H. doi:10.1038/500141a. PMC 5101952 . PMID 23925224.
  31. "Innovator Under 35: Jay Shendure, 31 – MIT Technology Review". MIT Technology Review . Archived from the original on September 29, 2009. Retrieved 2014年02月04日.
  32. "American Society of Human Genetics Honors Dr. Jay Shendure with Curt Stern Award for 2012" (PDF). American Society of Human Genetics. Archived from the original (PDF) on 2016年11月09日. Retrieved 2014年02月04日.
  33. "Prijswinnaar Federa 2013 | Stichting Federatie van Medisch Wetenschappelijke Verenigingen". Federa.org. Archived from the original on 2014年02月22日. Retrieved 2014年02月04日.
  34. "NIH Director's Pioneer Award Program – 2013 PioneerAward Recipients". NIH Common Fund. 2013年12月04日. Archived from the original on February 21, 2014. Retrieved 2014年02月04日.
  35. 1 2 3 Wimmer, Doris. "Jay Shendure". ESHG Conference 2022. Retrieved 2026年07月27日.
  36. "Recognizing local Clevelander Jay Shendure, MD, PhD," (PDF). The Lotus. Federation of India Community Associations. March 2020.

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